Advancements in Psoriasis Research: Skin Microcirculation and Its Prognostic Significance

Abstract

Psoriasis, a chronic and recurring inflammatory skin disorder, is distinguished by the excessive proliferation of keratinocytes, immune cell infiltration, and angiogenesis. Ever since the observation of microvascular hyperplasia in psoriatic lesions, there has been a growing focus on exploring the intricate relationship between microcirculation and psoriasis. Furthermore, the potential utility of microcirculatory changes as prognostic indicators for psoriasis has garnered significant attention. This paper provides a comprehensive review of the role of skin microcirculation in psoriasis pathogenesis and its potential application as a clinical prognostic indicator.