Advancements in screening systems for active ingredients in traditional Chinese medicines using ligand fishing technique

Qin, Yi; Yan, Ying; Zhou, Jie; Gao, Xun; Zhao, Longshan; Guan, Xuefeng

doi:10.1016/j.trac.2024.117983

TrAC Trends in Analytical Chemistry

2024

DOI: 10.1016/j.trac.2024.117983

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Advancements in screening systems for active ingredients in traditional Chinese medicines using ligand fishing technique

Yi Qin,

Ying Yan,

Jie Zhou

et al.

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Cited by 1 publication

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Recent Advances in Screening and Separating Active Components From Natural Products Based on High‐Speed Countercurrent Chromatography

Wang,

Huang,

Zhang

et al. 2024

J of Separation Science

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Natural products play a vital role in human health because people find that they can reduce the incidence of many diseases, such as cancer and cardiovascular diseases. Therefore, researchers have developed many effective techniques for screening and separating active compounds from natural products. High‐speed countercurrent chromatography is a unique unsupported liquid–liquid chromatography technology that has been widely used in the separation of natural products. In this paper, the research progress of screening and separating active components from natural products by combining high‐speed countercurrent chromatography technology with other technologies is reviewed from two aspects: pre‐column activity assay and post‐column activity assay. The purpose of this paper is to provide some theoretical support for the screening and separation of natural active compounds by high‐speed countercurrent chromatography. I hope that the contents summarized in this paper can provide more basis for the development of screening and separation of natural active compounds to realize large‐scale preparation.

show abstract

Recent Advances in Screening and Separating Active Components From Natural Products Based on High‐Speed Countercurrent Chromatography

Wang,

Huang,

Zhang

et al. 2024

J of Separation Science

View full text Add to dashboard Cite

show abstract

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Advancements in screening systems for active ingredients in traditional Chinese medicines using ligand fishing technique

Cited by 1 publication

References 77 publications

Recent Advances in Screening and Separating Active Components From Natural Products Based on High‐Speed Countercurrent Chromatography

Recent Advances in Screening and Separating Active Components From Natural Products Based on High‐Speed Countercurrent Chromatography

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