Abstract:Improving the performance of blood-contacting medical implants is a global health necessity aimed at reducing mortality and morbidity in patients with cardiovascular diseases. Surface modification of the biomaterials from which the implants are constructed has been used to reduce the risk of complications such as thrombosis and infection. Herein with a focus on vascular tissue engineering, we provide an overview of (a) fundamental hemodynamic considerations for blood-contacting biomaterials, (b) surface modifi… Show more
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