Advances and applications of biomimetic biomaterials for endogenous skin regeneration

Wang, Mengyang; Hong, Yiyue; Fu, Xiaobing; Sun, Xiaoyan

doi:10.1016/j.bioactmat.2024.04.011

Bioactive Materials

2024

DOI: 10.1016/j.bioactmat.2024.04.011

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Advances and applications of biomimetic biomaterials for endogenous skin regeneration

Mengyang Wang,

Yiyue Hong,

Xiaobing Fu

et al.

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2024

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MXene-reinforced bioactive polymer hydrogels for biomedical applications

Gu,

Chen,

Wei

et al. 2024

APL Materials

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MXenes, a novel class of two-dimensional (2D) materials, have attracted considerable attention in various fields, especially in drug delivery, wound healing, bone tissue engineering, biosensing, and cancer treatment. Thanks to their remarkable physicochemical properties, MXenes hold great promise for biomedical applications. Concurrently, hydrogels composed of polymers have been extensively utilized in biomedical contexts. The unique properties of MXenes facilitate their integration into various bioactive hydrogels with enhanced functions and properties, thereby endowing the composites with multifunctional capabilities. MXene-reinforced polymer hydrogels (MRPHs) synergistically combine the advantageous characteristics of both MXenes and hydrogels, making them highly adaptable for integration with other theranostic strategies in medical applications. In this comprehensive review, we demonstrate recent advances in the design and synthesis of MRPHs for biomedical applications. Specifically, we introduce the unique functions and properties of MRPHs and analyze the methods for tailoring the functions of MRPHs by incorporating them with other active components, including functional molecules, 2D materials, metal ions, natural polymers, and drugs/genes. We then discuss the biomedical applications of the designed bioactive MRPHs in wound healing, tissue engineering, biosensors, and cancer therapy. We hope that this work provides valuable guidance and inspiration for readers to develop novel MRPHs for advanced applications.

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MXene-reinforced bioactive polymer hydrogels for biomedical applications

Gu,

Chen,

Wei

et al. 2024

APL Materials

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show abstract

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Advances and applications of biomimetic biomaterials for endogenous skin regeneration

Cited by 1 publication

References 288 publications

MXene-reinforced bioactive polymer hydrogels for biomedical applications

MXene-reinforced bioactive polymer hydrogels for biomedical applications

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