Advances and strategies for capillary electrophoresis in the characterization of traditional Chinese medicine: A review of the past decade (2011–2021)

Shamsi, Shahab A.; Patel, Jalpaben

doi:10.3389/frans.2023.1059884

Cited by 2 publications

(1 citation statement)

References 146 publications

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“…CE is a cost-effective instrument that requires minimal reagents and offers high separation efficiency [ 116 ]. CE’s effectiveness can be enhanced through several methods including altering the buffer type, capillary type, pH, voltage and injection mode [ 117 ].…”

Section: Analysis Of Drug Residues In Foodmentioning

confidence: 99%

Recent Advances in the Determination of Veterinary Drug Residues in Food

Pratiwi,

Ramadhanti,

Amatulloh

et al. 2023

Foods

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The presence of drug residues in food products has become a growing concern because of the adverse health risks and regulatory implications. Drug residues in food refer to the presence of pharmaceutical compounds or their metabolites in products such as meat, fish, eggs, poultry and ready-to-eat foods, which are intended for human consumption. These residues can come from the use of drugs in the field of veterinary medicine, such as antibiotics, antiparasitic agents, growth promoters and other veterinary drugs given to livestock and aquaculture with the aim of providing them as prophylaxis, therapy and for promoting growth. Various analytical techniques are used for this purpose to control the maximum residue limit. Compliance with the maximum residue limit is very important for food manufacturers according to the Food and Drug Administration (FDA) or European Union (EU) regulations. Effective monitoring and control of drug residues in food requires continuous advances in analytical techniques. Few studies have been reviewed on sample extraction and preparation techniques as well as challenges and future directions for the determination of veterinary drug residues in food. This current review focuses on the overview of regulations, classifications and types of food, as well as the latest analytical methods that have been used in recent years (2020–2023) for the determination of drug residues in food so that appropriate methods and accurate results can be used. The results show that chromatography is still a widely used technique for the determination of drug residue in food. Other approaches have been developed including immunoassay, biosensors, electrophoresis and molecular-based methods. This review provides a new development method that has been used to control veterinary drug residue limit in food.

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Section: Analysis Of Drug Residues In Foodmentioning

confidence: 99%

Recent Advances in the Determination of Veterinary Drug Residues in Food

Pratiwi,

Ramadhanti,

Amatulloh

et al. 2023

Foods

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Analysis of cassine and spectaline in the Senna spectabilis ethanolic extracts by capillary zone electrophoresis with indirect UV detection

Barbosa,

Pivatto,

Cardoso

et al. 2024

Phytochemical Analysis

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Introduction2,6‐Disubstituted piperidin‐3‐ols are an important group of piperidine alkaloids found in species such as Senna spectabilis, whose main constituents include cassine and spectaline, compounds with relevant pharmacological activity. The analysis of these compounds is challenging due to the complexity of plant extracts and the absence of chromophores capable of absorbing ultraviolet (UV) radiation.ObjectiveThis paper presents a new analytical method to separate and quantify the non‐UV‐absorbing alkaloids present in ethanol extracts from S. spectabilis flowers using capillary zone electrophoresis (CZE) with indirect UV detection.MethodologyThe optimized CZE method employs a background electrolyte containing 60 mM histidine (His), 15 mM α‐cyclodextrin, 20% acetonitrile (ACN), and pH‐adjusted to 4.7 with acetic acid (AcOH).ResultsThe limit of detection (LOD) values was 10.2 and 13.9 mg L−1 for cassine and spectaline, respectively. For both analytes, the precision data were better than 2% of relative standard deviation (RSD) for migration times and peak areas. To evaluate the applicability of the developed method, ethanolic extracts from S. spectabilis flowers were prepared and analyzed.ConclusionsThereby, the method proved to be efficient and complementary to conventional techniques, offering a cost‐effective alternative in the quantification of the non‐UV‐absorbing piperidine alkaloids present in plant extracts.

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Advances and strategies for capillary electrophoresis in the characterization of traditional Chinese medicine: A review of the past decade (2011–2021)

Cited by 2 publications

References 146 publications

Recent Advances in the Determination of Veterinary Drug Residues in Food

Recent Advances in the Determination of Veterinary Drug Residues in Food

Analysis of cassine and spectaline in the Senna spectabilis ethanolic extracts by capillary zone electrophoresis with indirect UV detection

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