Advances in Biomimetic Apatite Coating on Metal Implants

Preparation and characterization of dopamine-induced biomimetic hydroxyapatite coatings on the AZ31 magnesium alloy

“…In addition, physical deposition techniques, such as electrodeposition and ion beam assisted deposition, involve high costs and sophisticated equipment. Compared with the abovementioned techniques, the biomimetic technique has the following advantages [13]: (i) the coating composition, phase and crystallinity can be readily adjusted; (ii) the method has no adverse effect on the substrate and biomimetic apatite coatings can be produced even on porous or complex-shaped implants; (iii) it is a simple and cost-effective method of incorporating biologically active agents or drugs into apatite coatings through coprecipitation rather than via mere adsorption on the surface. Owing to these unique advantages, the biomimetic method has been extensively employed for the modification of metallic biomaterials.…”

Preparation of Hydroxyapatite/Tannic Acid Coating to Enhance the Corrosion Resistance and Cytocompatibility of AZ31 Magnesium Alloys

“…In addition, the method of biomimetic mineralization can not only prepare a bone-like apatite coating on the surface of materials which have a complicated shape, but can also add bone growth-stimulating factors to the coating [16]. However, due to a lack of nucleation centers for hydroxyapatite growth, direct biomimetic deposition of hydroxyapatite on untreated AZ31 magnesium alloy is very difficult [17].…”

Effect of Dioxane and N-Methyl-2-pyrrolidone as a Solvent on Biocompatibility and Degradation Performance of PLGA/nHA Scaffolds

“…Formation of a biologically active bone-like apatite layer on artificial material is a necessary requirement for bonding to the living bone [34,35] . Bioactive materials are intended to induce a biological activity, which can lead to strong bonding to bone [36] .…”