Advances in chemokines of teleost fish species

Xu, Hongsen; Liu, Fuguo

doi:10.1016/j.aaf.2023.01.008

Cited by 8 publications

(8 citation statements)

References 137 publications

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“…In accordance, the expressions of cxcl8 (il-8) and ccl19 were increased in rainbow trout gill tissue after A. salmonicida infection [20]. Previously, studies on the teleost revealed that ccl19 promotes anti-viral and anti-bacterial defense and inflammation [68]. Further, in this study, we noticed an up-regulation of genes encoding interleukins and their receptors including il1b, il6, il11, il17d, il21, il1r2 and il13ra2.…”

Section: Discussionsupporting

confidence: 84%

Application of 4 × 44 Oligo Microarray to Transcriptomic Analysis of Immune Response in Rainbow Trout Infected with Aeromonas salmonicida

Małachowicz,

Siwicki,

Dobosz

et al. 2023

Applied Sciences

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Rainbow trout, one of the most economically important aquaculture fish species worldwide, is affected by the pathogenic bacteria A. salmonicida, which causes furunculosis outbreaks, leading to huge economic losses. In this study, an oligonucleotide microarray was applied to identify transcriptional changes in the skin of rainbow trout individuals in response to a bacterial infection. Overall, 656 and 434 differentially expressed genes (DEGs) were identified at 2 and 6 days after a bacterial challenge (dpi), respectively. A comparison of moribund (2 dpi) and survivor fish (6 dpi) revealed 169 DEGs. Between these were many genes involved in immune response, including lysozymes, pattern recognition receptors (c-type lectins), antimicrobial peptides (cathelicidin and hepcidin), acute-phase proteins (serum amyloids and haptoglobin), complement cascade proteins (c3, c4, c6 and c7), interleukins (il11 and il1b) and chemokines (ccl19 and cxcl8). Alterations of leptin, eicosanoids and prostaglandins have been found, which suggest metabolic remodeling in conjunction with immune response. Further, the regulation of programmed cell death genes (caspase 8, bcl2 apoptosis regulator, nfkb inhibitor alpha and heme oxygenase) and structural proteins (collagens, myosins, keratins and metalloproteinases) was observed. This study provides, for the first time, a gene expression analysis of rainbow trout skin in response to A. salmonicida infection, revealing the complexity of defense strategies in response to furunculosis.

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Section: Discussionsupporting

confidence: 84%

Application of 4 × 44 Oligo Microarray to Transcriptomic Analysis of Immune Response in Rainbow Trout Infected with Aeromonas salmonicida

Małachowicz,

Siwicki,

Dobosz

et al. 2023

Applied Sciences

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“…In this research, the peak expression level of CD83 and MHC-2α genes appeared earlier than CD3γ, CD8α, and CD28 genes. Chemokines played an important role in regulating cell migration and immune response, and have been viewed as a link between innate and adaptive immunity (Xu and Liu, 2023). As the systemic immunoglobulin, IgM and IgD mediate the adaptive immune response by antibody dependent cell-mediated cytotoxicity, opsonisation, and complement activation (Qian et al, 2023).…”

Section: Discussionmentioning

confidence: 99%

Pathogenicity of Streptococcus iniae causing mass mortalities of yellow catfish (Tachysurus fulvidraco) and its induced host immune response

Xu,

Zhu,

Chen

et al. 2024

Front. Microbiol.

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The outbreak of mass mortality occurred in Tachysurus fulvidraco farm in Hubei province of China. The pathogenic strain of Streptococcus iniae (termed 2022SI08) was isolated and identified from diseased T. fulvidraco, based on morphological, physiological, and biochemical characteristics, as well as 16S rRNA gene sequence and phylogenetic analysis. Further, the whole genome of isolate S. iniae was sequenced and predicted to contain one single circular chromosome of 1,776,777 bp with a GC content of 37.14%. The genomic sequence analysis showed that 2022SI08 was positive for 204 virulent and 127 antibiotic resistant genes. The experimental challenge demonstrated the high pathogenicity of the retrieved isolate of S. iniae, with a median lethal dosage (LD50) 9.53 × 105 CFU/g. Histopathological examination indicated that the 2022SI08 strain could induce extensive tissue cell degeneration, necrosis, hemorrhage, and inflammation in the skin, gill, fin, spleen, liver, kidney, intestine, eye, and brain. Moreover, the innate immune enzyme activities in serum such as acid phosphatase and alkaline phosphatase were increased significantly at 24 and 48 h post infection (hpi) and then decreased at 168 hpi. The transcriptional profile of immune associated gene in T. fulvidraco following bacterial infection was detected at each point of time, and the results revealed clear transcriptional activation of those genes, which proving their reacting and regulatory role during the response of the host against S. iniae infection. The results revealed that S. iniae was an etiological agent in the mass mortalities of T. fulvidraco and this research will be conducive for increasing our understanding on pathogenesis and host defensive system in S. iniae invasion.

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“…The number of the support plates (4) is two, the top surfaces of the two support plates (4) are fixedly connected with movable rails (5), the end faces of the movable rails ( 5) are fixedly connected with connecting plates (6), and a rotating shaft (7) is movably sleeved between the two supporting plates (4). A gear (8) is fixedly sleeved on the outer surface of the rotating shaft (7) and meshes with the gear groove (3). A side plate (9) is fixedly installed on the end face of the connecting plate (6), a power box (10) is fixedly installed on the front face of the side plate (9), and a movable bait-casting vehicle (11) is movably installed on the top surfaces of the movable rails (5).…”

Section: Design and Workflow Of The Feeding Devicementioning

confidence: 99%

“…The development of aquaculture engineering ships is a new direction for the future development of the aquaculture industry. The aquaculture engineering ship is a closed aquaculture system based on a ship platform [3] , which realizes the organic combination between the aquaculture space and the overall ship, therefore constructing an ecological, efficient and intensive pattern of cabin culture. Compared with offshore aquaculture, the aquaculture engineering ship has the advantages of conveniently exchanging water environment, breeding fry in a full-cycle manner, and effectively avoiding offshore aquaculture pollution.…”

Section: Introductionmentioning

confidence: 99%