Advances in Collagen/Hydroxyapatite Composite Materials

Ficai, Anton; Andronescu, Ecaterina; Voicu, Georgeta; Ficai, Denisa

doi:10.5772/13707

Cited by 28 publications

(29 citation statements)

References 55 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…709 Besides FTIR spectroscopy, other measurement techniques are also able to show some evidence of a chemical interaction among the phases in calcium orthophosphate-based biocomposites and hybrid biomaterials. 345,462,635,638,641,[1134][1135][1136][1137][1138] For example, for nano-sized crystals of CDHA/alendronate such evidence was obtained by thermogravimetric analysis: DTG plots of the while a bond among the matrix and reinforcements must exist for the purpose of stress transfer, it should not be so strong that it prevents toughening mechanisms, such as debonding and fiber pullout. 217 There is still doubt as to the exact bonding mechanism among bone minerals (biological apatite) and bioorganics (collagen), which undoubtedly plays a critical role in determining the mechanical properties of bones.…”

mentioning

confidence: 99%

“…708,709 More to the point, nucleation of apatite crystals onto collagen through a chemical interaction with carboxylate groups of collagen macromolecules has been reported in references 1130-1132. FTIR spectroscopy seems to be the major tool for studying a possible chemical bonding among the phases in calcium orthophosphate-based biocomposites and hybrid biomaterials. 276,310,345,353,355,462,513,600,616,629,635,638,641,644,653,664,673,678,709,753,802,803,847,882,[1133][1134][1135][1136] For example, the characteristic bands at 2,918, …”

mentioning

confidence: 99%

See 1 more Smart Citation

Biocomposites and hybrid biomaterials based on calcium orthophosphates

Dorozhkin¹

2011

Biomatter

156

View full text Add to dashboard Cite

show abstract

mentioning

confidence: 99%

mentioning

confidence: 99%

Biocomposites and hybrid biomaterials based on calcium orthophosphates

Dorozhkin¹

2011

Biomatter

156

View full text Add to dashboard Cite

show abstract

“…In CH-PVA/HA nano composites, the surface of HA nanoparticles will contact with the CH and PVA molecules to make a coordination bond between Ca 2? and RCOO -in CH molecules and a strong interact between the hydroxyl groups on the surface of HA and PVA hydrophilic molecules (Chang and Tanaka 2002a, b;Ficai et al 2009;Kim et al 2008;Peng and Kong 2007). These reactions were influenced on tertiary weight loss stage of CH-PVA blend materials.…”

Section: Thermal Behavior and Experimental Design Optimizationmentioning

confidence: 99%

Synthesis and character investigation of new collagen Hydrolysate/polyvinyl alcohol/hydroxyapatite Polymer-Nano-Porous Membranes: I. Experimental design optimization in thermal and structural properties

Imanieh¹,

Aghahosseini²

2013

Syst Synth Biol

View full text Add to dashboard Cite

Development of bioorganic-inorganic composites has drawn eyes to extensive attention in biomedical fields and tissue engineering. So many attempts to prepare hydroxyapatite (HA), in conjunction with various binders including polyvinyl alcohol (PVA), and collagen has performed for late 20 years. We applied a method based on the phase separation for making of polymer porous membranes. This procedure is induced through the addition of a small quantity of water (polymer-rich phase) to a solution with HA precursors (polymer-poor phase). Thermal and structural composite properties of collagen Hydrolysate (CH)-PVA/HA Polymer-Nano-Porous Membranes were analyzed by Design of experiment that was undertaken using D-optimal approach, to select the optimal combination of nano composites precursor. The resulted composite characters were investigated by Fourier transform infrared, scanning electron microscopy (SEM) and thermal gravimetric analysis. Based on the SEM images, this new method could be clearly concluded to porous CH-PVA/HA hybrid materials. Finally the hemocompatibility of nanocomposite membranes were evaluated by the hemolysis study.

show abstract

“…Previously, hydroxyapatite/chitosan bone scaffold has been produced with the pore size of 100-300 μm using thermally induced phase separation (TIPS) method [5]. However, its compressive strength was reported to be lower than the biomechanical properties of healthy bone [10].…”

Section: Introductionmentioning

confidence: 99%