Advances in Hollow Inorganic Nanomedicines for Photothermal-Based Therapies

Chen, Ling; Wang, Xiaobo; Shen, Yan

doi:10.2147/ijn.s285115

Cited by 14 publications

(11 citation statements)

References 154 publications

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“…Therefore, the development of NIR-II PTAs has become more and more popular [ 44 , 90 , 93 , 146 , 147 ]. Though organic nanomaterials especially conjugated polymers prove to be excellent NIR-II PTAs, the corresponding hollow structures are seldom reported [ 86 ]. So past studies have focused mainly on the design of various inorganic NIR-II hollow nanoplatforms including carbon-based, Au-based and metal chalcogenide nanomaterials, etc.…”

Section: Hollow Nanoplatforms For Single Nir-ii Pttmentioning

confidence: 99%

Recent advances in near-infrared-II hollow nanoplatforms for photothermal-based cancer treatment

et al. 2022

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Near-infrared-II (NIR-II, 1000–1700 nm) light-triggered photothermal therapy (PTT) has been regarded as a promising candidate for cancer treatment, but PTT alone often fails to achieve satisfactory curative outcomes. Hollow nanoplatforms prove to be attractive in the biomedical field owing to the merits including good biocompatibility, intrinsic physical-chemical nature and unique hollow structures, etc. On one hand, hollow nanoplatforms themselves can be NIR-II photothermal agents (PTAs), the cavities of which are able to carry diverse therapeutic units to realize multi-modal therapies. On the other hand, NIR-II PTAs are capable of decorating on the surface to combine with the functions of components encapsulated inside the hollow nanoplatforms for synergistic cancer treatment. Notably, PTAs generally can serve as good photoacoustic imaging (PAI) contrast agents (CAs), which means such kind of hollow nanoplatforms are also expected to be multifunctional all-in-one nanotheranostics. In this review, the recent advances of NIR-II hollow nanoplatforms for single-modal PTT, dual-modal PTT/photodynamic therapy (PDT), PTT/chemotherapy, PTT/catalytic therapy and PTT/gas therapy as well as multi-modal PTT/chemodynamic therapy (CDT)/chemotherapy, PTT/chemo/gene therapy and PTT/PDT/CDT/starvation therapy (ST)/immunotherapy are summarized for the first time. Before these, the typical synthetic strategies for hollow structures are presented, and lastly, potential challenges and perspectives related to these novel paradigms for future research and clinical translation are discussed. Graphical Abstract

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Section: Hollow Nanoplatforms For Single Nir-ii Pttmentioning

confidence: 99%

Recent advances in near-infrared-II hollow nanoplatforms for photothermal-based cancer treatment

et al. 2022

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“…Generally speaking, inorganic PTAs have higher PCE and better photothermal stability than organic PTAs, but organic PTAs have greater biodegradability and biocompatibility compared to inorganic PTAs [ 25 , 51 ]. With a large number of studies on spherical and rod-like morphologies, the exploration of two-dimensional (2D) nanomaterials in the fields of sensing [ 52 , 53 ], catalysis [ 54 ], device manufacturing [ 55 ], and energy storage [ 56 , 57 ] has increased greatly in recent years [ 58 ].…”

Section: Photothermal Transduction Agentsmentioning

confidence: 99%

Antitumor Applications of Photothermal Agents and Photothermal Synergistic Therapies

Cheng

et al. 2022

IJMS

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As a new tumor treatment strategy, photothermal therapy (PTT) has the advantages of accuracy, ease of administration, a high efficiency and low side effects. Photothermal transduction agents (PTAs) are the key factor which play an important role in PTT. The mechanism of PTT is discussed in detail. The photothermal conversion efficiency (PCE) can be improved by increasing the light absorption and reducing the light scattering of photothermal conversion agents. Additionally, non-radiative relaxation path attenuation can also promote energy conversion to obtain a higher value in terms of PCE. The structure and photothermal characteristics of various kinds of PTAs (metal materials, carbon-based nanomaterials, two-dimensional nanomaterials, and organic materials) were compared and analyzed. This paper reviews the antitumor applications of photothermal synergistic therapies, including PTT combined with immunotherapy, chemotherapy, and photodynamic therapy. This review proposes that these PTAs promote the development of photothermal synergistic therapies and have a great potential in the application of tumor treatment.

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“…This treatment is characterized by minimal invasiveness and excellent tissue penetration. Gold nanoparticles have received much attention because of their unique photothermal conversion properties and LSPR properties ( Bi et al, 2019 ; Ling et al, 2021 ). The high affinity of tumor cells for the applied gold nanoparticles should have an efficient photothermal effect, so appropriate receptors or ligands should be modified on the particle surface to enable tumor-specific targeting ( Grabowska-Jadach et al, 2019 ; Xu et al, 2021 ).…”

Section: Biomedical Applications Of Hollow Gold Nanostructuresmentioning

confidence: 99%

Recent Advances in Hollow Gold Nanostructures for Biomedical Applications

et al. 2021

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The localized surface plasmon resonance of metallic nanoparticles has attracted much attention owing to its unique characteristics, including the enhancement of signals in sensors and photothermal effects. In particular, hollow gold nanostructures are highly promising for practical applications, with significant advantages being found in their material properties and structures: 1) the interaction between the outer surface plasmon mode and inner cavity mode leads to a greater resonance, allowing it to absorb near-infrared light, which can readily penetrate tissue; 2) it has anti-corrosiveness and good biocompatibility, which makes it suitable for biomedical applications; 3) it shows a reduced net density and large surface area, allowing the possibility of nanocarriers for drug delivery. In this review, we present information on the classification, characteristics, and synthetic methods of hollow gold nanostructures; discuss the recent advances in hollow gold nanostructures in biomedical applications, including biosensing, bioimaging, photothermal therapy, and drug delivery; and report on the existing challenges and prospects for hollow gold nanostructures.

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Advances in Hollow Inorganic Nanomedicines for Photothermal-Based Therapies

Cited by 14 publications

References 154 publications

Recent advances in near-infrared-II hollow nanoplatforms for photothermal-based cancer treatment

Recent advances in near-infrared-II hollow nanoplatforms for photothermal-based cancer treatment

Antitumor Applications of Photothermal Agents and Photothermal Synergistic Therapies

Recent Advances in Hollow Gold Nanostructures for Biomedical Applications

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