Advances in Imaging and Automated Quantification of Pulmonary Diseases in Non-neoplastic Diseases

Balbinot, Fernanda; Guedes, Álvaro da Costa Batista; Nascimento, Douglas Zaione; Zampieri, Juliana Fischman; Alves, Giordano Rafael Tronco; Marchiori, Edson; Rubin, Adalberto Sperb; Hochhegger, Bruno

doi:10.1007/s00408-016-9940-x

Cited by 4 publications

(4 citation statements)

References 67 publications

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“…Another method refers to imaging studies. Although computed tomography (CT) cannot reflect pathological findings, it can show a wide range of airway/lung morphology and quantitatively evaluate the airway size to obtain the lumen diameter, wall thickness, total airway area, and lumen area in crosssection 103 .…”

Section: Evaluation Methods Of Airway Remodelingmentioning

confidence: 99%

How does cigarette smoking affect airway remodeling in asthmatics?

Lin¹,

Li²

2023

Tob. Induc. Dis.

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Asthma is a prevalent chronic airway inflammatory disease involving multiple cells, and the prolonged course of the disease can cause airway remodeling, resulting in irreversible or partial irreversible airflow limitation and persistent airway hyperresponsiveness (AHR) in asthmatics. Therefore, we must ascertain the factors that affect the occurrence and development of airway remodeling in asthmatics. Smokers are not uncommon in asthmatics. However, there is no systematic description of how smoking promotes airway remodeling in asthmatics. This narrative review summarizes the effects of smoking on airway remodeling in asthmatics, and the progress of the methods for evaluating airway remodeling.

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Section: Evaluation Methods Of Airway Remodelingmentioning

confidence: 99%

How does cigarette smoking affect airway remodeling in asthmatics?

Lin¹,

Li²

2023

Tob. Induc. Dis.

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“…Mediciones basadas en la densidad pulMonar -Porcentaje de pulmón con densidad normal (definido como el porcentaje de volumen pulmonar con atenuación normal de −950 a −701 UH): el volumen de pulmón total es singificativamente más útil que el porcentaje de CVF predicha y la capacidad de difusión del pulmón para monóxido de carbono 11 .…”

Section: Mediciones Parenquimatosasunclassified

“…Consiste en la elección de un punto en la escala del percentil donde el porcentaje acumulado de los vóxeles es menor que el valor de corte, y determinar la atenuación correspondiente en ese punto, sobre el histograma de frecuencias de la atenuación pulmonar. El percentil 15 se ha propuesto como medida de destrucción parenquimatosa 11 . Existe evidencia de que el abordaje por percentiles es más fuerte para la evaluación longitudinal del enfisema, y menos sensible a cambios en los volúmenes pulmonares.…”

Section: Mediciones Parenquimatosasunclassified

Volumetría pulmonar por tomografía computada en enfermedad pulmonar obstructiva crónica: mediciones básicas para fenotipificar al paciente

Hernández-Morales¹,

Pensado-Piedra²,

Juárez-Hernández³

et al. 2022

ARM

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La enfermedad pulmonar obstructiva crónica (EPOC) es una de las principales causas de morbilidad y mortalidad en todo el mundo. Actualmente, las diferentes modalidades de imagen proporcionan una evaluación morfológica y funcional para su diagnóstico, pronóstico y seguimiento. Esta revisión da a conocer las principales medidas tomográficas que tienen repercusión en la fenotipificación del paciente y, por tanto, en el proceso de atención.

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“…TB research focused on imaging or genomic data analysis has recently achieved significant success [12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24]; however, there are still few investigations that encompass clinical, socioeconomic, image, and genomic data. Most TB databases and resources are domain specific, including ReSeqTB [25], PATRIC [26, 27], TB DB [28], ChestX-ray8: hospital-scale chest X-ray database [29] and others.…”

Section: Introductionmentioning

confidence: 99%

TB DEPOT (Data Exploration Portal): A multi-domain tuberculosis data analysis resource

et al. 2019

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The NIAID TB Portals Program (TBPP) established a unique and growing database repository of socioeconomic, geographic, clinical, laboratory, radiological, and genomic data from patient cases of drug-resistant tuberculosis (DR-TB). Currently, there are 2,428 total cases from nine country sites (Azerbaijan, Belarus, Moldova, Georgia, Romania, China, India, Kazakhstan, and South Africa), 1,611 (66%) of which are multidrug- or extensively-drug resistant and 1,185 (49%), 863 (36%), and 952 (39%) of which contain X-ray, computed tomography (CT) scan, and genomic data, respectively. We introduce the Data Exploration Portal (TB DEPOT, https://depot.tbportals.niaid.nih.gov ) to visualize and analyze these multi-domain data. The TB DEPOT leverages the TBPP integration of clinical, socioeconomic, genomic, and imaging data into standardized formats and enables user-driven, repeatable, and reproducible analyses. It furthers the TBPP goals to provide a web-enabled analytics platform to countries with a high burden of multidrug-resistant TB (MDR-TB) but limited IT resources and inaccessible data, and enables the reusability of data, in conformity with the NIH’s Findable, Accessible, Interoperable, and Reusable (FAIR) principles. TB DEPOT provides access to “analysis-ready” data and the ability to generate and test complex clinically-oriented hypotheses instantaneously with minimal statistical background and data processing skills. TB DEPOT is also promising for enhancing medical training and furnishing well annotated, hard to find, MDR-TB patient cases. TB DEPOT, as part of TBPP, further fosters collaborative research efforts to better understand drug-resistant tuberculosis and aid in the development of novel diagnostics and personalized treatment regimens.

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Advances in Imaging and Automated Quantification of Pulmonary Diseases in Non-neoplastic Diseases

Cited by 4 publications

References 67 publications

How does cigarette smoking affect airway remodeling in asthmatics?

How does cigarette smoking affect airway remodeling in asthmatics?

Volumetría pulmonar por tomografía computada en enfermedad pulmonar obstructiva crónica: mediciones básicas para fenotipificar al paciente

TB DEPOT (Data Exploration Portal): A multi-domain tuberculosis data analysis resource

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