Advances in Investigation of Ullmann Reaction Accelerated by Microwave Irradiation

Abstract

The Ullmann reaction has been extensively applied in the synthesis of organic intermediates, especially in the formation of carbon-carbon bond, carbon-oxygen bond, carbon-sulfur bond and carbon-nitrogen bond. It has been demonstrated that microwave irradiation can obviously accelerate the Ullmann reaction and improve the yields, so the application of microwave in the Ullmann reaction has caught increasing attention in recent years. The application of microwave in the Ullmann reaction and the progresses in the formation of carbon-carbon bond, carbon-oxygen bond, carbon-sulfur bond and carbon-nitrogen bond are reviewed in this paper. Keywords Ullmann reaction; microwave; synthesis; review 经典的 Ullmann 反应是指以两芳基卤代物为原料, 在铜粉催化作用下, 生成二芳基化合物 2 (Eq. 1)的反应. 不过, 该反应可以采用不同的过渡金属进行催化 [1] . 尽管 Ullmann 反应的应用广泛, 但是该类反应一般

Porous aromatic networks with amine linkers for adsorption of hydroxylated aromatic hydrocarbons

“…In this paper, two target porous aromatic networks with amine linkers were prepared. Ullmann protocol and Buchwald–Hartwig protocol were compared in synthesis yield and BET surface area of the products. Then, adsorption properties of the two porous COPs were investigated using phenol and 2‐naphthol as model adsorbates.…”

“…The Ullmann method with copper as catalyst is a common and cheap way for coupling of arylamine and arylhalide in synthesis of small organic molecules . The results for synthesis of COP 1 by Ullmann protocol are listed in Table .…”