Advances in Polysaccharide-Based Antimicrobial Delivery Vehicles

Pawar, Vaishali; Bavya, M. C.; Rohan, K. Vimal; Srivastava, Rohit

doi:10.1007/978-3-030-34475-7_12

Cited by 2 publications

(4 citation statements)

References 139 publications

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“…Guar gum is a non-ionic polysaccharide. It is extracted from the seeds of Cyamopsis tetragonolobus and consists of a linear chain of (1-4)-β-D-mannopyranosil units with α-D-galactopyranosyl units attached by (1)(2)(3)(4)(5)(6) ramifications. This polysaccharide presents an extraordinarily viscous property due to its intermolecular chain entanglement of galactose side chains.…”

Section: Guar Gummentioning

confidence: 99%

“…Dextran is a complex branched glucan consisting of α-D-(1-6) glycosidic links and branched at α- (1)(2)(3). It is obtained naturally from the lactic acid bacterium.…”

Section: Dextranmentioning

confidence: 99%

“…Arabinoxylans (AX) are non-starch polysaccharides found mainly in the cell wall, outer layer, and endosperm of cereals. The AX are composed of a linear chain of β- (1)(2)(3)(4) xylose units branched to arabinose units in positions C(O)-3 and C(O)-2. Arabinose can be esterified with monomeric or dimeric ferulic acid (AF).…”

Section: Arabinoxylansmentioning

confidence: 99%

“…The polysaccharides chain comprises monosaccharide units linked by glycosidic bonds with hydroxyl, carboxyl, and amino groups. Carbohydrates are stable, non-toxic, hydrophilic, and biodegradable biomolecules in the human body [1,2]. Polysaccharides can be used as matrices for encapsulation, immobilization, and controlled release for many active compounds.…”

Section: Introductionmentioning

confidence: 99%

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Polysaccharide-Based Nanoparticles for Colon-Targeted Drug Delivery Systems

et al. 2021

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Polysaccharide biomaterials have gained significant importance in the manufacture of nanoparticles used in colon-targeted drug delivery systems. These systems are a form of non-invasive oral therapy used in the treatment of various diseases. To achieve successful colonic delivery, the chemical, enzymatic and mucoadhesive barriers within the gastrointestinal (GI) tract must be analyzed. This will allow for the nanomaterials to cross these barriers and reach the colon. This review provides information on the development of nanoparticles made from various polysaccharides, which can overcome multiple barriers along the GI tract and affect encapsulation efficiency, drug protection, and release mechanisms upon arrival in the colon. Also, there is information disclosed about the size of the nanoparticles that are usually involved in the mechanisms of diffusion through the barriers in the GI tract, which may influence early drug degradation and release in the digestive tract.

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Section: Guar Gummentioning

confidence: 99%

“…Dextran is a complex branched glucan consisting of α-D-(1-6) glycosidic links and branched at α- (1)(2)(3). It is obtained naturally from the lactic acid bacterium.…”

Section: Dextranmentioning

confidence: 99%