Advances in reconstructive options of nerve injuries in the hand

Bíró, Vilmos

doi:10.1556/oh.2012.29480

Cited by 3 publications

(2 citation statements)

References 11 publications

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“…The recovery of sensory function requires not only quality nerve suture, but also the use of drugs on promoting nerve regeneration to accelerate neurological recovery [14]. The earlier the sensation occurs, the better the sensory function recovers [15]. Its mechanism of action is as follows: methyl VitB 12 can transfer into cell organelle of nerve cells flexibly, with a higher content in peripheral nerves, compared with ordinary VitB 12 [16].…”

Section: Discussionmentioning

confidence: 99%

Effects of Postoperative Methycobal Administration on Digital Replantation Based on Stellate Ganglion Stimulation

Wang¹

2017

AJIM

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Abstract:To study the impact of stellate ganglion block (SGB) on digital replantation and analyze its mechanism. Digital arterial diameter was enlarged after SGB, and the difference in the survival rate of severed finger after replantation was not statistically significant between the two groups (P>0.05). Through the treatment with Methycobal, the recovery of 2-point discrimination (2-pd) of the experimental groups (A, B) was significantly better than that of the negative control group, between which the difference was statistically significant (P<0.01 between Groups A and C, P<0.05 between Groups B and C), indicating that the methyl vitamin B 12 can significantly promote the regeneration of peripheral nerves. Methycobal is of great significance to the postoperative treatment of digital replantation, which is worthy of being widely applied in clinic practice.

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Section: Discussionmentioning

confidence: 99%

Effects of Postoperative Methycobal Administration on Digital Replantation Based on Stellate Ganglion Stimulation

Wang¹

2017

AJIM

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“…A new bulk of knowledge turned into a common property related to the micro-and macroanatomic structure of peripheral nerves, the process of nerve regeneration, and the technical conditions of nerve reconstructive operations. This knowledge is a prerequisite for hand surgeons to perform their nerve reconstructive operations on a contemporary high level with an optimal result [46]. In nerve injury with nervous gap, no restitution method was found better than the autograft, however, it has the disadvantage of damaging a normal nerve to be used as a graft.…”

Section: Nerve Regenerationmentioning

confidence: 99%

The Relevant Roles of Plastic and Orthopedic Surgery in Hand Salvage

Almutlaq¹,

Al‐Qattan²,

Alturkstani³

et al. 2018

MPS

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Over the recent past few years, there is a huge innovation in plastic surgery and orthopedic surgery through implantation of new techniques, which enabled a great level of success in hand salvage. Conditions such as trauma, tumor, sepsis, or vascular disease, may necessitate hand salvage. The most frequent argument among surgeon from different subspecialties (orthopedics, plastics, trauma, and vascular surgery) are characterized by in what way each one can do his own part of the salvage operation, be it bony fixation, revascularization, or soft-tissue coverage, but none of them is sure whether it should be endeavored. What is necessary in such clinical situations is an interdisciplinary team attitude led by individual or groups of clinicians who are conversant not only with their identifiable subspecialized skills but also with those of their coworkers and the consequences accompanying the joined efforts at hand salvage. The perception of orthoplastic surgery is based on such an indication, where the integrated skills and techniques of the orthopedic surgeon and reconstructive microsurgeon are performed in recital to direct efforts concerning hand salvage or choose against it when it is not designated. The current article reviews the roles of orthopedic and plastic surgery and how this team can deal with the existing techniques to improve outcomes in hand salvage surgery.

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The role of mesenchymal stem cells in the reconstruction of nerve injuries in the hand

Bíró

2013

Orvosi Hetilap

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At present the end results of reconstruction of peripheral nerve injuries cannot be considered unequivocally advantageous. It seems that the level of reconstructive possibilities of these injuries has already peaked. Hence, ongoing research focuses on experimental studies to further improve results. One of the methods is the joint usage of pluripotent mesenchymal stem cells with tissue inductive polypeptides (growth factors) and frame structures to enhance the attachment of these cells with the aim creating new neural tissue (tissue engineering). The conditions to create new tissue can be further improved by gene technology. Based on recent literature data, the author summarizes the basic characteristics of the method related to nerve injuries, and the possibilities and modalities of clinical applications. In conclusion, future direction is a the wider use of stem cells, however, the currently established surgical and rehabilitation methods have to be performed at high levels since stem cell research data are not established in the clinical setting yet.

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Advances in reconstructive options of nerve injuries in the hand

Cited by 3 publications

References 11 publications

Effects of Postoperative Methycobal Administration on Digital Replantation Based on Stellate Ganglion Stimulation

Effects of Postoperative Methycobal Administration on Digital Replantation Based on Stellate Ganglion Stimulation

The Relevant Roles of Plastic and Orthopedic Surgery in Hand Salvage

The role of mesenchymal stem cells in the reconstruction of nerve injuries in the hand

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