2024
DOI: 10.3389/fendo.2024.1340436
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Advances in risk predictive performance of pre-symptomatic type 1 diabetes via the multiplex Antibody-Detection-by-Agglutination-PCR assay

Devangkumar Tandel,
Brigette Hinton,
Felipe de Jesus Cortez
et al.

Abstract: IntroductionAchieving early diagnosis of pre-symptomatic type 1 diabetes is critical to reduce potentially life-threatening diabetic ketoacidosis (DKA) at symptom onset, link patients to FDA approved therapeutics that can delay disease progression and support novel interventional drugs development. The presence of two or more islet autoantibodies in pre-symptomatic type 1 diabetes patients indicates high-risk of progression to clinical manifestation.MethodHerein, we characterized the capability of multiplex AD… Show more

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