Advances in solid-phase extraction techniques: Role of nanosorbents for the enrichment of antibiotics for analytical quantification

Suseela, M. Nikitha Lakshmi; Viswanadh, Matte Kasi; Mehata, Abhishesh Kumar; Priya, Vishnu; Setia, Vikas Aseem; Malik, Ankit Kumar; Gokul, Patharaj; Selvin, Joseph; Muthu, Madaswamy S

doi:10.1016/j.chroma.2023.463937

Cited by 39 publications

(6 citation statements)

References 156 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Alternatively, solid-phase extraction technique has been considered as a relatively “green” separation method with high separation efficiency due to the possibility of column mode operation and easy scale-up options. Extraction chromatography, which uses solid adsorbents whose pores contain the selective organic extractant for selective extraction of the metal ion of interest, has attracted the attention of researchers working in the area of nuclear fuel cycle processes due to simplicity, ease of operation, recovery of elements, stability and reusability of absorbent, safety with respect to hazardous reagents/samples, and consumption of less organic solvents, which have a positive impact on the economics and safety toward extraction of spent nuclear fuel radionuclides …”

Section: Introductionmentioning

confidence: 99%

First Report on a 1-Cycle Solid-Phase Extraction Method for Selective Separation of Am³⁺ and Eu³⁺: Use of BTP-Grafted Silica Decorated on Activated Carbon

Ansari,

Gujar,

Bhattacharyya

et al. 2024

Ind. Eng. Chem. Res.

View full text Add to dashboard Cite

A new composite sorbent material was prepared by grafting bistriazinylpyridine (BTP) onto silica and then blending it with activated charcoal (AC− Si−BTP) for the selective separation of Am 3+ over Eu 3+ using a 1-cycle solid-phase extraction for the direct separation of lanthanides from actinides. BTP was attached to silica via a sulfonamide bond between R−BTP and amino silane, and the resulting Si− BTP was covalently bonded to activated carbon (AC) with a favorable orientation of the ligand coordination sites. The material exhibited a significantly large distribution coefficient for Am 3+ over Eu 3+ at lower acidities (<0.5 M HNO 3 ), and the separation factor between the two metal ions was found to be maximum in 0.2 M HNO 3 with a value of 110. The loading capacity of the material was 4.05 ± 0.12 mg of Eu per gram of the composite when investigated at pH 3. The radiation stability of the material was excellent when studied up to an absorbed dose of 1000 kGy. The material was tested for the separation of Am 3+ and Eu 3+ in a column mode, which gave selective loading of Am 3+ over Eu 3+ . The reusability studies indicated slow leaching of the BTP fraction from the solid, with a resultant decrease of the K d values with time. To address this issue, the material was embedded in polysulfone beads for a separate set of studies, but the separation efficiencies were found to be comparable.

show abstract

Section: Introductionmentioning

confidence: 99%

First Report on a 1-Cycle Solid-Phase Extraction Method for Selective Separation of Am³⁺ and Eu³⁺: Use of BTP-Grafted Silica Decorated on Activated Carbon

Ansari,

Gujar,

Bhattacharyya

et al. 2024

Ind. Eng. Chem. Res.

View full text Add to dashboard Cite

show abstract

“…This measurement method offers high accuracy and sensitivity and is highly versatile. In contrast, SPE, a sample pre-treatment operation, is generally performed manually by humans, and the SPE instruments and related products available on the market are mainly syringe barrel-type products for measuring one sample at a time or cartridge-type products for connecting syringes [33,34]. Therefore, to establish a system for the nationwide development of environmental water monitoring surveys for AMR, developing and implementing a high-throughput analysis (HTA) system that can process multiple samples simultaneously and that excels in speed and accuracy is essential [35,36].…”

Section: Introductionmentioning

confidence: 99%

Development of a High-Throughput Analytical Method for Antimicrobials in Wastewater Using an Automated Pipetting and Solid-Phase Extraction System

Azuma,

Matsunaga,

Ohmagari

et al. 2024

Antibiotics

View full text Add to dashboard Cite

Antimicrobial resistance (AMR) has emerged and spread globally. Recent studies have also reported the presence of antimicrobials in a wide variety of aquatic environments. Conducting a nationwide monitoring survey of AMR in the environment to elucidate its status and to assess its impact on ecosystems and human health is of social importance. In this study, we developed a novel high-throughput analysis (HTA) system based on a 96-well plate solid-phase extraction (SPE), using automated pipetting and an SPE pre-treatment system. The effectiveness of the system as an HTA for antimicrobials in environmental water was verified by comparing it with a conventional manual analytical system in a domestic hospital over a period of two years and four months. The results of the manual analysis and HTA using a combination of automated pipetting and SPE systems were generally consistent, and no statistically significant difference was observed (p > 0.05) between the two systems. The agreement ratios between the measured concentrations based on the conventional and HTA methods were positively correlated with a correlation coefficient of r = 0.99. These results indicate that HTA, which combines automated pipetting and an SPE pre-treatment system for rapid, high-volume analysis, can be used as an effective approach for understanding the environmental contamination of antimicrobials at multiple sites. To the best of our knowledge, this is the first report to present the accuracy and agreement between concentrations based on a manual analysis and those measured using HTA in hospital wastewater. These findings contribute to a comprehensive understanding of antimicrobials in aquatic environments and assess the ecological and human health risks associated with antimicrobials and antimicrobial-resistant bacteria to maintain the safety of aquatic environments.

show abstract

“…33 The term "sample cleanup" describes the enrichment or extraction of specified analytes from simple or complicated matrices. 34 This step is commonly followed by chromatographic techniques which then separate the extracted targeted analytes from the complex mixtures. 35 The drawbacks of the SPE sorbent are its low selectivity, single-use nature, time-consuming nature due to many manual steps involved (sorbent conditioning and equilibration, sample loading, impurity removal, and extract elution), which may require concentrating the extract prior to instrumental analysis.…”

Section: Introductionmentioning

confidence: 99%

“…Currently, this is by far the most advanced method for using MIPs to prepare samples. , Following Sellergren and colleagues ground-breaking work in 1994 for the extraction of pentamidine from human urine samples, molecularly imprinted solid-phase extraction (MISPE) has attracted significant interest for the detection of several pharmaceuticals in biological matrices. , Consequently, solid-phase extraction (SPE), which uses stationary phases like nonpolar polymer or C18-bonded silica, is the most used technique for the extraction and cleanup of solutes of interest . The term “sample cleanup” describes the enrichment or extraction of specified analytes from simple or complicated matrices . This step is commonly followed by chromatographic techniques which then separate the extracted targeted analytes from the complex mixtures .…”

Section: Introductionmentioning

confidence: 99%

Molecularly Imprinted Polymer-Based Adsorbents for the Selective Removal of Pharmaceuticals from Wastewater: Adsorption Kinetics, Isotherms, and Thermodynamics Studies

Nxumalo,

Mahlambi

2023

Ind. Eng. Chem. Res.

View full text Add to dashboard Cite

The majority of pharmaceuticals are found in the environment as mixtures. However, a significant amount of these therapeutic compounds cannot be completely metabolized by the human body; thus, they are excreted through feces and urine and end up in wastewater treatment plants (WWTPs). The presence of pharmaceuticals and the degree to which they can be removed during wastewater treatment are now important research topics. Despite the adoption of various alternative technologies for the treatment of wastewater, the adsorption process is still regarded as a promising method due to its high efficiency, increased simplicity, and lower costs. Recent developments in the adsorption process involve the incorporation of an artificial molecularly imprinted polymer (MIP), which is a potent molecular receptor capable of selectively recognizing and removing pollutants. The MIP has advantageous characteristics, which include high affinity, predetermination, high stability, ease of preparation, and low cost. Notably, MIPs can be applied to the cleanup and preconcentration of analytes as the selective adsorbent of solid-phase extraction (SPE), magnetic solid phase extraction (MSPE), and dispersive solid-phase extraction (dSPE). Furthermore, MIPs can be produced as composite nanomaterials by employing nanoparticles (nanoMIP). The advancements of MIPs employed as sorbent materials for quantitative assessment and purification of pharmaceuticals in environmental water have been given most of the focus. Therefore, this study not only aims to present the fundamental ideas about the application of MIPs as sorbents but also gives an overview of the considerable initiatives made in recent years to enhance the performance of MIPs. Considering this, various current approaches to the development of MIP-based extraction techniques are detailed in the present review. This review also demonstrates how kinetics, thermodynamics, and isotherm models can be used to better understand the behavior of adsorbents and the adsorption process.

show abstract

Advances in solid-phase extraction techniques: Role of nanosorbents for the enrichment of antibiotics for analytical quantification

Cited by 39 publications

References 156 publications

First Report on a 1-Cycle Solid-Phase Extraction Method for Selective Separation of Am³⁺ and Eu³⁺: Use of BTP-Grafted Silica Decorated on Activated Carbon

First Report on a 1-Cycle Solid-Phase Extraction Method for Selective Separation of Am³⁺ and Eu³⁺: Use of BTP-Grafted Silica Decorated on Activated Carbon

Development of a High-Throughput Analytical Method for Antimicrobials in Wastewater Using an Automated Pipetting and Solid-Phase Extraction System

Molecularly Imprinted Polymer-Based Adsorbents for the Selective Removal of Pharmaceuticals from Wastewater: Adsorption Kinetics, Isotherms, and Thermodynamics Studies

Contact Info

Product

Resources

About

Advances in solid-phase extraction techniques: Role of nanosorbents for the enrichment of antibiotics for analytical quantification

Cited by 39 publications

References 156 publications

First Report on a 1-Cycle Solid-Phase Extraction Method for Selective Separation of Am3+ and Eu3+: Use of BTP-Grafted Silica Decorated on Activated Carbon

First Report on a 1-Cycle Solid-Phase Extraction Method for Selective Separation of Am3+ and Eu3+: Use of BTP-Grafted Silica Decorated on Activated Carbon

Development of a High-Throughput Analytical Method for Antimicrobials in Wastewater Using an Automated Pipetting and Solid-Phase Extraction System

Molecularly Imprinted Polymer-Based Adsorbents for the Selective Removal of Pharmaceuticals from Wastewater: Adsorption Kinetics, Isotherms, and Thermodynamics Studies

Contact Info

Product

Resources

About

First Report on a 1-Cycle Solid-Phase Extraction Method for Selective Separation of Am³⁺ and Eu³⁺: Use of BTP-Grafted Silica Decorated on Activated Carbon

First Report on a 1-Cycle Solid-Phase Extraction Method for Selective Separation of Am³⁺ and Eu³⁺: Use of BTP-Grafted Silica Decorated on Activated Carbon