Advances in the Study of the Structures and Bioactivities of Metabolites Isolated from Mangrove-Derived Fungi in the South  China Sea

Wang, Xinxin; Mao, Zhigang; Song, Bingbing; Chen, Chunhua; Xiao, Weiwei; Wang, Jiwen; Jiang, Xiaobing; Zhu, Yu Cheng; Wang, Haijun

doi:10.3390/md11103601

Cited by 29 publications

(19 citation statements)

References 49 publications

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“…As far as bostrycin is concerned, the originally proposed structure [ 119 , 120 , 121 ] was revised by Kelly and his co-workers in 1985 [ 122 ] on the basis of the total synthesis of (+/−)-bostrycin and an X-ray crystal structure of the O -isopropylidene derivative. This revision also concerns its derivative 4-deoxybostrycin found in serveral marine isolates [ 68 , 84 , 86 , 101 , 123 ].…”

Section: Anthraquinones From Marine-derived Fungimentioning

confidence: 99%

Anthraquinones and Derivatives from Marine-Derived Fungi: Structural Diversity and Selected Biological Activities

et al. 2016

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Anthraquinones and their derivatives constitute a large group of quinoid compounds with about 700 molecules described. They are widespread in fungi and their chemical diversity and biological activities recently attracted attention of industries in such fields as pharmaceuticals, clothes dyeing, and food colorants. Their positive and/or negative effect(s) due to the 9,10-anthracenedione structure and its substituents are still not clearly understood and their potential roles or effects on human health are today strongly discussed among scientists. As marine microorganisms recently appeared as producers of an astonishing variety of structurally unique secondary metabolites, they may represent a promising resource for identifying new candidates for therapeutic drugs or daily additives. Within this review, we investigate the present knowledge about the anthraquinones and derivatives listed to date from marine-derived filamentous fungi′s productions. This overview highlights the molecules which have been identified in microorganisms for the first time. The structures and colors of the anthraquinoid compounds come along with the known roles of some molecules in the life of the organisms. Some specific biological activities are also described. This may help to open doors towards innovative natural substances.

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Section: Anthraquinones From Marine-derived Fungimentioning

confidence: 99%

Anthraquinones and Derivatives from Marine-Derived Fungi: Structural Diversity and Selected Biological Activities

et al. 2016

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“…More than 1300 coumarins have been identified as secondary metabolites from plants, bacteria, and fungi (Hwang et al 2013;Venugopala et al 2013;Wang et al 2013;Islam et al 2015). The name coumarin comes from a French term for the Tonka bean, coumarou (Dipteryx odorata), isolated by Vogel, 1820 (Venugopala et al 2013;Rohini and Srikumar 2014;Matos et al 2015).…”

Section: Introductionmentioning

confidence: 99%

Fungi as a source of natural coumarins production

Costa

Tavares

Oliveira

2016

Appl Microbiol Biotechnol

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Natural coumarins and derivatives are compounds that occur naturally in several organisms (plant, bacteria, and fungi) consisting of fused benzene and α-pyrone rings. These compounds show high technological potential applications in agrochemical, food, pharmaceuticals, and cosmetics industries. Therefore, the need for bulk production of coumarins and the advancement of the chemical and pharmaceutical industries led to the development of synthetic coumarin. However, biotransformation process, synthetic bioengineering, metabolic engineering, and bioinformatics have proven effective in the production of natural products. Today, these biological systems are recognized as green chemistry innovation and business strategy. This review article aims to report the potential of fungi for synthesis of coumarin. These microorganisms are described as a source of natural products capable of synthesizing many bioactive metabolites. The features, classification, properties, and industrial applications of natural coumarins as well as new molecules obtained by basidiomycetes and ascomycetes fungi are reported in order to explore a topic not yet discussed in the scientific literature.

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“…The antimicrobial activities of an increasing number of fungi living in distinctive environments are being investigated for the discovery of new antibacterial and antifungal compounds, such as endophytic fungi from wild plants and marine fungi. In the last decade, many novel bioactive natural products from marine fungi have been discovered that possess cytotoxic, anticancer, antiviral, antibacterial or antifungal activities [ 1 , 2 , 3 , 4 , 5 , 6 ]. The antibacterial and antifungal compounds from marine fungi have quickly increased since 2010, and marine fungi have been an important source of antibacterial and antifungal compounds.…”

Section: Introductionmentioning

confidence: 99%

Antibacterial and Antifungal Compounds from Marine Fungi

et al. 2015

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This paper reviews 116 new compounds with antifungal or antibacterial activities as well as 169 other known antimicrobial compounds, with a specific focus on January 2010 through March 2015. Furthermore, the phylogeny of the fungi producing these antibacterial or antifungal compounds was analyzed. The new methods used to isolate marine fungi that possess antibacterial or antifungal activities as well as the relationship between structure and activity are shown in this review.

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Advances in the Study of the Structures and Bioactivities of Metabolites Isolated from Mangrove-Derived Fungi in the South China Sea

Cited by 29 publications

References 49 publications

Anthraquinones and Derivatives from Marine-Derived Fungi: Structural Diversity and Selected Biological Activities

Anthraquinones and Derivatives from Marine-Derived Fungi: Structural Diversity and Selected Biological Activities

Fungi as a source of natural coumarins production

Antibacterial and Antifungal Compounds from Marine Fungi

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