Advances in Tumor Markers for the Early Diagnosis of Papillary Thyroid Carcinoma

Huang, Gailing; Liu, Ying; Cao, Difei; Yu, Gong; Su, Dan; Zhao, Junping; Wang, Lei

doi:10.22159/ijpps.2016v8s2.15221

Cited by 2 publications

(2 citation statements)

References 28 publications

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“…The most common pathological type of thyroid cancer is papillary adenocarcinoma that accounts for ~70%, followed by follicular adenocarcinoma, medullary carcinoma and undifferentiated carcinoma (17). At present, the key to the treatment of thyroid cancer remains how to make the early diagnosis and intervention therapy (18). Ultrasound, which is commonly used in clinical practice, is an auxiliary diagnostic method of thyroid cancer, but the ultrasound images of thyroid cancer are overlapping and diverse, so ultrasound has a high misdiagnosis rate of atypical and early thyroid cancers (19).…”

Section: Discussionmentioning

confidence: 99%

Diagnostic value of fine-needle aspiration combined with ultrasound for thyroid cancer

Wang

et al. 2019

Oncol Lett

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Diagnostic value of fine-needle aspiration (FNA) combined with ultrasound for thyroid cancer was evaluated. A retrospective analysis was performed on the preoperative FNA and ultrasound data of 165 thyroid nodule patients, were divided into group A (≤1 cm group) and group B (>1 cm group) based on the maximum diameter line of the thyroid nodule. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of FNA, ultrasound and FNA combined with ultrasound in the diagnosis of thyroid cancer were analyzed and compared. In group A (≤1 cm group), the sensitivity, specificity, accuracy, positive predictive value and negative predictive value of FNA in the diagnosis of thyroid cancer were 93.33, 71.43, 91.04, 96.55 and 55.56%, respectively, those of ultrasound were 86.67, 28.57, 80.60, 91.23 and 20%, respectively, and those of FNA combined with ultrasound were 100, 28.57, 92.54, 92.6 and 100%, respectively, with statistically significant differences in the sensitivity, specificity, accuracy, positive predictive value and negative predictive value between FNA, ultrasound and FNA combined with ultrasound (P<0.05). In group B, the sensitivity, specificity, accuracy, positive predictive value and negative predictive value of FNA in the diagnosis of thyroid cancer were 100, 54.55, 94.90, 94.57 and 100%, respectively, those of ultrasound were 96.55, 72.73, 93.88, 96.55 and 72.73%, respectively, and those of FNA combined with ultrasound were 100, 63.64, 97.96, 95.92 and 100%, respectively, without statistically significant differences in the sensitivity, specificity, accuracy, positive predictive value and negative predictive value between FNA, ultrasound and FNA combined with ultrasound (P>0.05). FNA combined with ultrasound significantly improved the sensitivity and accuracy in the diagnosis of the thyroid nodule in group A, but it did not significantly improve the accuracy, sensitivity and specificity in the diagnosis of the thyroid nodule in group B.

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Section: Discussionmentioning

confidence: 99%

Diagnostic value of fine-needle aspiration combined with ultrasound for thyroid cancer

Wang

et al. 2019

Oncol Lett

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“…Thyroid is an intermediate sensitive organ; therefore, the exposure to radiation can increase the risk of cancer. Thyroid cancer is the most frequent endocrine cancer and one of the most distressing diseases [5,6]. The estimated radiation dose to thyroid in Chernobyl accident showed a mean value of approximately 0.2 mGy in thyroid cancer cases [7].…”

Section: Introductionmentioning

confidence: 99%

Estimation of Entrance Surface Radiation Dose to Thyroid Region in Computed Tomography Brain Examination

Visakh¹,

Sukumar²,

Pradhan³

2019

Asian J Pharm Clin Res

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Objective: The objective of this study was to estimate the entrance surface radiation dose to the thyroid region in a computed tomography (CT) brain scan.Methods: Unfors Multi-O-Meter equipment was used to measure the entrance surface at the thyroid region of adult patients ranging from 18 to 70 years of age. A total of 115 patients were included in the study based on convenience sampling. The Multi-O-Meter was kept at the thyroid region during the scan, and the values for entrance surface dose (ESD) were noted from its monitor after the scan was complete.Results: The obtained data were analyzed and violate normal distribution; therefore, the median and quartiles were computed. The overall median (Q1, Q2), ESD of the patients, was 1.335 (1.213, 1.529) mGy. The minimum and maximum dose values recorded were 1.015 mGy and 1.964 mGy, respectively.Conclusions: The result showed a significant amount of entrance surface radiation dose to the thyroid region while taking a brain scan. This data can be used for optimization of radiation protection while undergoing CT scans of brain to reduce exposure to thyroid region.

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Advances in Tumor Markers for the Early Diagnosis of Papillary Thyroid Carcinoma

Cited by 2 publications

References 28 publications

Diagnostic value of fine-needle aspiration combined with ultrasound for thyroid cancer

Diagnostic value of fine-needle aspiration combined with ultrasound for thyroid cancer

Estimation of Entrance Surface Radiation Dose to Thyroid Region in Computed Tomography Brain Examination

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