2023
DOI: 10.1016/j.scitotenv.2022.160589
|View full text |Cite
|
Sign up to set email alerts
|

Advances in understanding mechanisms underlying mitochondrial structure and function damage by ozone

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

0
9
0

Year Published

2023
2023
2024
2024

Publication Types

Select...
8

Relationship

0
8

Authors

Journals

citations
Cited by 16 publications
(9 citation statements)
references
References 101 publications
0
9
0
Order By: Relevance
“…However, a study published in Nature Geoscience suggested that PM 2.5 could inhibit O 3 chemical production through non-homogeneous absorption of hydroperoxyl (HO2) radicals and nitrogen oxide (NOx) [ 30 ]. Moreover, it is well-known that PM 2.5 and O 3 can cause oxidative damage in humans, which may result in competition between the two pollutants for target organs [ 31 , 32 ]. Thus, it is plausible that the co-exposure to PM 2.5 and O 3 may have an antagonistic effect on hepatocellular injury.…”
Section: Discussionmentioning
confidence: 99%
“…However, a study published in Nature Geoscience suggested that PM 2.5 could inhibit O 3 chemical production through non-homogeneous absorption of hydroperoxyl (HO2) radicals and nitrogen oxide (NOx) [ 30 ]. Moreover, it is well-known that PM 2.5 and O 3 can cause oxidative damage in humans, which may result in competition between the two pollutants for target organs [ 31 , 32 ]. Thus, it is plausible that the co-exposure to PM 2.5 and O 3 may have an antagonistic effect on hepatocellular injury.…”
Section: Discussionmentioning
confidence: 99%
“…Mitochondrial ROS acts upstream of Cl − efflux and is considered as commonly upstream of NLRP3, AIM2, NLRC4 inflammasome, and pyroptosis. Besides, PIM-1 plays a regulatory role in mitochondrial integrity, which is related to the production of mitochondrial ROS [ 49 , 50 ]. Therefore, PIM-1 may participate in NLRP3 inflammasome activation and pyroptosis by mediating mitochondrial ROS production.…”
Section: Discussionmentioning
confidence: 99%
“…118 However, excessive ROS can cause irreversible cell oxidative damage by oxidizing proteins and destroying DNA structure. 119 Therefore, increasing the ROS content and discussing the dynamic feature at the tumor or bacterial infection site have been an effective strategy for cancer and bacterial treatment. Recently, nanozymes have been extensively used in ROS-mediated EDT due to the OXD or POD-simulated characteristics and ROS generation feature.…”
Section: Ros Producing-initiated Edtmentioning
confidence: 99%
“…In general, ROS could mediate signal transduction and cell growth at the proper concentration 118 . However, excessive ROS can cause irreversible cell oxidative damage by oxidizing proteins and destroying DNA structure 119 . Therefore, increasing the ROS content and discussing the dynamic feature at the tumor or bacterial infection site have been an effective strategy for cancer and bacterial treatment.…”
Section: Enzyodynamic Therapy (Edt) For Versatile Disease Treatmentsmentioning
confidence: 99%