The Food-Energy-Water (FEW) nexus for urban sustainability needs to be analyzed via an integrative rather than a sectoral or silo approach, reflecting the ongoing transition from separate infrastructure systems to an integrated social-ecological-infrastructure system. As technology hubs can provide food, energy, water resources via decentralized and/or centralized facilities, there is an acute need to optimize FEW infrastructures by considering cost-benefit-risk tradeoffs with respect to multiple sustainability indicators. This paper identifies, categorizes, and analyzes global trends with respect to contemporary FEW technology metrics that highlights the possible optimal integration of a broad spectrum of technology hubs for possible cost-benefit-risk tradeoffs. The challenges related to multiscale and multiagent modeling processes for the simulation of urban FEW systems were discussed with respect to the aspects of scaling-up, optimization process, and risk assessment. Our review reveals that this field is growing at a rapid pace and the previous selection of analytical methodologies, nexus criteria, and sustainability indicators largely depended on individual FEW nexus conditions disparately, and full-scale cost-benefit-risk tradeoffs were very rare. Therefore, the potential full-scale technology integration in three ongoing cases of urban FEW systems in Miami (the United States), Marseille (France), and Amsterdam (the Netherlands) were demonstrated in due purpose finally.