Advances in viscosupplementation and tribosupplementation for early-stage osteoarthritis therapy

DeMoya, Christian D.; Joenathan, Anisha; Lawson, Taylor B.; Felson, David T.; Schaer, Thomas P.; Bais, Manish; Albro, Michael B.; Mäkelä, Janne; Snyder, Brian D.; Grinstaff, Mark W.

doi:10.1038/s41584-024-01125-5

Nat Rev Rheumatol

2024

DOI: 10.1038/s41584-024-01125-5

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Advances in viscosupplementation and tribosupplementation for early-stage osteoarthritis therapy

Christian D. DeMoya,

Anisha Joenathan,

Taylor B. Lawson

et al.

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Cited by 3 publications

References 156 publications

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Nanomaterials: Recent Advances in Knee Osteoarthritis Treatment

Peng,

Wang,

Bai

et al. 2024

Adv Healthcare Materials

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Osteoarthritis (OA) of the knee is the most prevalent degenerative joint condition that places a substantial financial and medical burden on society. However, due to drawbacks such as inefficiency, adverse effects, and brief duration of action, the clinical efficacy of the current major therapies for knee OA is largely restricted. Therefore, novel medication development is highly required to address these issues. Numerous studies in recent years have established that nanomaterials can be a potential and highly effective way to overcome these challenges. In this review, the anatomical distinctions between healthy and OA knee joints, as well as novel advances in the field of nanomaterials for the treatment of knee OA are summarized. The limits of the present therapeutic strategies for treating knee OA are also highlighted, as well as the potential prospects of nanomaterials in the future.

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Nanomaterials: Recent Advances in Knee Osteoarthritis Treatment

Peng,

Wang,

Bai

et al. 2024

Adv Healthcare Materials

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Construction of hydrogels with specific structures and functions for cartilage defects and traumatic osteoarthritis: A review

Peng,

Zhou,

Luo

et al. 2025

Chemical Engineering Journal

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Grafting of cationic molecules to hyaluronic acid improves adsorption and cartilage lubrication

Gonzales,

Hoque,

Kaeo

et al. 2024

Biomater. Sci.

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Advances in viscosupplementation and tribosupplementation for early-stage osteoarthritis therapy

Cited by 3 publications

References 156 publications

Nanomaterials: Recent Advances in Knee Osteoarthritis Treatment

Nanomaterials: Recent Advances in Knee Osteoarthritis Treatment

Construction of hydrogels with specific structures and functions for cartilage defects and traumatic osteoarthritis: A review

Grafting of cationic molecules to hyaluronic acid improves adsorption and cartilage lubrication

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