Advances of cassava starch-based composites in novel and conventional drug delivery systems: a state-of-the-art review

Das, Sanjoy; Das, Malay K.; Jamatia, Taison; Bhattacharya, Bireswar; Mazumder, Rishav; Yadav, Pradip Kumar; Ghose Bishwas, Nayan Ranjan; Deka, Trinayan; Roy, Dhritiman; Sinha, Bibek; Das, Biplajit; Daule, Ichu; Paul, Kishan; Roy, Ankita; Choudhury, Ankita; Sadhukhan, Pinkan; Sarmah, Dibyojyoti; Bhargab, Dhritiman; Jana, Bani Kumar; Tayeng, Dubom; Guha, Nilayan; Kalita, Bhrigumani; Mandal, Subhajit

doi:10.1039/d3pm00008g

Cited by 4 publications

(1 citation statement)

References 254 publications

(194 reference statements)

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“…Cassava starch contains both amylose, which exists in an amorphous phase, and amylopectin, which mostly remains in the form of crystals . The prominent diffraction peaks at 2θ = 15.34°, 17.42°, 18.22°, and 23.24° present in the X-ray diffractogram of the cassava starch powder shown in Figure S1, corresponds to the peaks originating from the semicrystalline domains of amylopectin present in the CS powder. , However, to probe the structure of cassava starch after fabricating the films, X-ray diffraction is performed. As can be inferred from the obtained X-ray diffractogram, depicted in Figure (c), a broad peak at 2θ = 20°confirms the CS films are found to be fully amorphous in nature.…”

Section: Resultsmentioning

confidence: 99%

Vapor and Light Responsive Biocompatible Soft Actuator

Kumar,

Satapathy

2024

Langmuir

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Bioinspired smart polymeric materials that undergo three-dimensional shape deformation in response to specific stimuli have gained significant attention in the field of soft robotics and intelligent devices. Despite the substantial advancements in soft robotics, there is a growing demand for the design of multistimuli-responsive soft actuators using a single layer of material due to its reduced complexity and ease of manufacturing and durability. Here, we report the actuation characteristics of a single-layer, dual-responsive soft actuator that overcomes the commonly encountered delamination issues often associated with bilayer systems by incorporating PEDOT:PSS with cassava starch. This soft actuator exhibits deformations in response to various solvent vapors, such as water, alcohol, and acetone. Remarkably, it demonstrates opposite deformations upon exposure to water and alcohol vapors. Additionally, the actuator responds to light triggers and folds upon exposure to sunlight and infrared light. The degree of folding can be precisely controlled by adjusting the intensity of the light source. Furthermore, the periodic geometric patterns imposed on the surface of the actuator provide an additional handle to control the bending axis. For proof of concept, we leverage the actuation capabilities of our actuator to showcase a range of potential applications, including its usage in wearable textiles, crawler robots, smart curtains, push-and-pull machines, and smart lifts.

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Section: Resultsmentioning

confidence: 99%

Vapor and Light Responsive Biocompatible Soft Actuator

Kumar,

Satapathy

2024

Langmuir

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Cassava Starch–Based Copolymer Gel with Surfactant: A Sustainable, High-Performance Solution for Environmentally Friendly Coal-Dust Suppression in Industrial Mining

Ilele,

Nie,

Akanyange

et al. 2024

J. Environ. Eng.

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Effect of Degree of Substitution and Polymer Ratio on the Structure of Chitosan: Carboxymethyl Starch (Bio)Polyelectrolyte Complexes

Castro,

Brovina,

Litvinov

et al. 2024

Polymers

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In this work, three carboxymethyl starches (CMS) were obtained by the two-step reaction process of carboxymethylation with different degrees of substitution (0.16, 0.33, and 0.36). From these samples, (bio)polyelectrolyte complexes ((bio)PECs) were obtained with chitosan (Chit) by the mixing of individual solutions of polymers (0.25 wt.%) at different volume ratios. The effect of the biopolymer and ionized groups of z ratios, pH, and degree of substitution of CMS in the formation of PEC were evaluated by turbidimetry and dynamic light scattering. The results showed that increasing the amount of CMS samples (ratio of z) led to an increase in the efficiency of the formation of (bio)PEC using CMS with a high DS value. Using the turbidimetry method for the chitosan and CMS mixtures, it was observed that the formation of (bio)PEC is divided into four transition zones delimited by pH transition points, and the stoichiometric complexation (z = 1) is achieved at a pH that displayed morphological changes “pHmorph”, which is a single point for Chit:CMS 1, and for Chit:CMS 2 and Chit:CMS 3, this is a range of 4.9–6.4 and 4.3–6.4, respectively. Analysis of the structural properties of the structures of (bio)PECs by dynamic light scattering was characterized by monomodal distribution, and the main observed effect was associated with an increase in the value of Davg with an increase in the ratio of Chit:CMS.

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Advances of cassava starch-based composites in novel and conventional drug delivery systems: a state-of-the-art review

Abstract: Native cassava starch and its derivatives have found great use in the pharmaceutical sector for the development of various novel and conventional drug delivery carriers.

Cited by 4 publications

References 254 publications

Vapor and Light Responsive Biocompatible Soft Actuator

Vapor and Light Responsive Biocompatible Soft Actuator

Cassava Starch–Based Copolymer Gel with Surfactant: A Sustainable, High-Performance Solution for Environmentally Friendly Coal-Dust Suppression in Industrial Mining

Effect of Degree of Substitution and Polymer Ratio on the Structure of Chitosan: Carboxymethyl Starch (Bio)Polyelectrolyte Complexes

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