Advances of graphene nanoparticles in dental implant applications – A review

Mobarak, Md Hosne; Hossain, Nayem; Hossain, Amran; Mim, Juhi Jannat; Khan, Fardin; Rayhan, Md Thohid; Islam, Md Aminul; Chowdhury, Mohammad Asaduzzaman

doi:10.1016/j.apsadv.2023.100470

Cited by 18 publications

(10 citation statements)

References 273 publications

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“…The proliferation and differentiation of stem cells occur on scaffolds. Tissue engineering scaffolds have been developed using graphene‐based materials in several studies 37 . Implants are osseointegrated into the bone through a process called osteointegration.…”

Section: Tissue Engineering Innovations For Enhancing Osseointegrationmentioning

confidence: 99%

“…Dental implants’ biocompatibility and mechanical properties have also been improved through graphene‐doped poly(methyl‐methacrylate) materials. Graphene nanoparticles can enhance the osseointegration of dental implants with surrounding bone tissues, which is one of their main advantages 37,72–74 . To secure the implant firmly, this must be done.…”

Section: Tissue Engineering Innovations For Enhancing Osseointegrationmentioning

confidence: 99%

“…Graphene nanoparticles are currently being explored for human biomedical applications, which could lead to significant advancements in dental implant technology. These advances make biologically compatible, resilient, and effective tooth replacements available 17,20,37,75 …”

Section: Tissue Engineering Innovations For Enhancing Osseointegrationmentioning

confidence: 99%

“…The binary titanium zirconium (TiZr) alloy maintains biocompatibility by maintaining its alpha structure in the same manner as cpTi. The surface is also unaffected by sandblasting, large grit, or acid etching 37 . The improved strength of TiZr makes it an ideal candidate for use in small‐diameter implants 65 …”

Section: Tissue Engineering Innovations For Enhancing Osseointegrationmentioning

confidence: 99%

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Tissue engineering innovations to enhance osseointegration in immediate dental implant loading: A narrative review

Saleh Hasani Jebelli,

Yari,

Nikparto

et al. 2024

Cell Biochemistry & Function

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The demand for efficient and accelerated osseointegration in dental implantology has led to the exploration of innovative tissue engineering strategies. Immediate implant loading reduces treatment duration and necessitates robust osseointegration to ensure long‐term implant success. This review article discusses the current studies of tissue engineering innovations for enhancing osseointegration in immediate dental implant loading in the recent decade. Keywords “tissue engineering,” “osseointegration,” “immediate implant loading,” and related terms were systematically searched. The review highlights the potential of bioactive materials and growth factor delivery systems in promoting osteogenic activity and accelerating bone regeneration. The in vivo experiment demonstrates significantly improved osseointegration in the experimental group compared to traditional immediate loading techniques, as evidenced by histological analyses and biomechanical assessments. It is possible to revolutionize the treatment outcomes and patient satisfaction in dental implants by integrating bioactive materials and growth factors.

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Section: Tissue Engineering Innovations For Enhancing Osseointegrationmentioning

confidence: 99%

Section: Tissue Engineering Innovations For Enhancing Osseointegrationmentioning

confidence: 99%

Section: Tissue Engineering Innovations For Enhancing Osseointegrationmentioning

confidence: 99%

Section: Tissue Engineering Innovations For Enhancing Osseointegrationmentioning

confidence: 99%

See 2 more Smart Citations

Tissue engineering innovations to enhance osseointegration in immediate dental implant loading: A narrative review

Saleh Hasani Jebelli,

Yari,

Nikparto

et al. 2024

Cell Biochemistry & Function

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“…Graphene and its composites find diverse biomedical applications, encompassing gene-and small-molecule-drug delivery [17,18]. These outcomes could play a crucial role in protein delivery and anticancer therapy, and serve as antimicrobial agents for bone and tooth implants [19,20]. Modified GO serves as an effective carrier for gene delivery, demonstrating its versatility in biomedical contexts [21].…”

Section: Introductionmentioning

confidence: 99%

Fine-Tuned Graphene Oxide Nanocomposite: Harnessing Copper(II)–Imidazole Complex for Enhanced Biological Responses and Balanced Photocatalytic Functionality

Sundaram,

Kumaravelu,

Tseng

et al. 2024

Materials

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In this study, the synthesis of biologically active copper(II) complex [Cu(im)2]Cl2 was achieved using a reported method. Subsequently, this copper(II) complex was strategically grafted onto graphene oxide, resulting in the formation of a nanocomposite denoted as copper(II)-complex-grafted graphene oxide (Cu-GO). The comprehensive characterization of Cu-GO was conducted through various techniques, including X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FT-IR), UV–visible spectroscopy, emission spectra analysis, X-ray photoelectron spectroscopy (XPS), and Copper K-edge X-ray Absorption Near Edge Structure (XANES) spectroscopy. The antibacterial efficacy of Cu-GO compounds was assessed using disk diffusion and microbroth dilution methods. Notably, the copper complex exhibited the highest effectiveness, showcasing a Minimal Inhibitory Concentration (MIC) value of 500 µL against Klebsiella bacteria. The antibacterial activities of all compounds were systematically screened, revealing the superior performance of the copper complex compared to standalone copper compounds. Expanding the scope of the investigation, we explored the antioxidant and anti-obesity activities of the copper complexes against Klebsiella organisms. The results underscore promising directions for the further exploration of the diverse health-related applications of these compounds. Moreover, the photocatalytic performance of the Cu-GO nanocomposite was evaluated under sunlight irradiation. Notably, the antioxidant and anti-obesity activities of Cu-GO, assessed in terms of percentage inhibition at a concentration of 200 mg/mL, exhibited values of 41% and 45%, respectively. Additionally, the Cu-GO composite exhibited exceptional efficacy, achieving a degradation efficiency of 74% for RhB under sunlight irradiation, surpassing both graphite and GO. These findings not only demonstrate enhanced biological activity, but also highlight a notable level of moderate photocatalytic performance. Such dual functionality underscores the potential versatility of Cu-GO nanocomposites across various applications, blending heightened biological efficacy with controlled photocatalysis. Our study offers valuable insights into the multifunctional attributes of copper(II)-complex-grafted graphene oxide nanocomposites, thereby paving the way for their broader utilization in diverse fields.

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