Advances on microfluidic paper-based electroanalytical devices

Holman, Joseph Benjamin; Shi, Zhengdi; Fadahunsi, Adeola Abraham; Li, Chengpan; Ding, Weiping

doi:10.1016/j.biotechadv.2022.108093

Cited by 22 publications

(7 citation statements)

References 203 publications

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“…Paper has the advantages of being inexpensive, being easy to obtain and having a high specific surface area, making it the most common medium in porous [ 26 , 37 ]. Paper consists essentially of a random distribution of cellulose, and the flow of liquid in paper is dominated by capillary [ 1 , 154 ].…”

Section: Relevant Principles In Microchannels and Hydrodynamically Re...mentioning

confidence: 99%

“…In 1952, Martin and Synge invented paper-based chromatographic separation technology and won the Nobel Prize in Chemistry [ 25 ]. Since then, paper-based microfluidic devices have been widely used in detection and medical treatment, and there are many related literatures reviewing their related applications [ 1 , 8 , 26 ]. In addition, with the development of microelectronics technology in recent years, another porous material commonly used in the field of biomedical detection is polymers such as PDMS.…”

Section: Introductionmentioning

confidence: 99%

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Porous Structural Microfluidic Device for Biomedical Diagnosis: A Review

et al. 2023

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Microfluidics has recently received more and more attention in applications such as biomedical, chemical and medicine. With the development of microelectronics technology as well as material science in recent years, microfluidic devices have made great progress. Porous structures as a discontinuous medium in which the special flow phenomena of fluids lead to their potential and special applications in microfluidics offer a unique way to develop completely new microfluidic chips. In this article, we firstly introduce the fabrication methods for porous structures of different materials. Then, the physical effects of microfluid flow in porous media and their related physical models are discussed. Finally, the state-of-the-art porous microfluidic chips and their applications in biomedicine are summarized, and we present the current problems and future directions in this field.

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Section: Relevant Principles In Microchannels and Hydrodynamically Re...mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Porous Structural Microfluidic Device for Biomedical Diagnosis: A Review

et al. 2023

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“…[8][9][10][11] Electrochemical analysis, a widely used method for metal ion detection, is an attractive alternative detection scheme for mPADs due to its small size, portability, high sensitivity with the proper choice of electrode material. [12][13][14] In water environmental applications, it is difficult to avoid interference from the coexisting ions or other components in water during electrochemical analysis of metal ions. To address this issue, various sensing materials have been widely investigated for electrochemical sensors to promote their performances in real-world application.…”

Section: Introductionmentioning

confidence: 99%

Ion imprinted polymers integrated into a multi-functional microfluidic paper-based analytical device for trace cadmium detection in water

Hu,

Wang,

Song

et al. 2024

Anal. Methods

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“…LC–MS/MS has been combined with multiple reaction monitoring for the analysis of Rac. , Electrochemical systems offer unique advantages for overcoming the shortcoming of the aforementioned methods. − The apparatus for electrochemical analysis is relatively cheap and easy to operate, and according to a previous study, Rac detection can be completed in 10 min by using this apparatus . The aforementioned apparatus can be made portable by using microfluidic chips or paper microfluidic devices. , Finally, electrochemical analysis has been used for detecting a wide range of biomolecules without the need for pretreatment or separation …”

Section: Introductionmentioning

confidence: 99%

“…25 The aforementioned apparatus can be made portable by using microfluidic chips or paper microfluidic devices. 26,27 Finally, electrochemical analysis has been used for detecting a wide range of biomolecules without the need for pretreatment or separation. 28 Nanoparticles (NPs) are valued for their large surface area, catalytic activity, and distinctive physical and chemical characteristics.…”

Section: Introductionmentioning

confidence: 99%