Advancing the science of management of arrhythmic disease in children and adult congenital heart disease patients within the last 25 years

Paul, Thomas; Krause, Ulrich; Sanatani, Shubhayan; Etheridge, Susan P

doi:10.1093/europace/euad155

Cited by 10 publications

(2 citation statements)

References 115 publications

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“…Ventricular pre-excitation occurs when an AP, a strand of myocardial cells with specific electrophysiological characteristics, activates both ventricles prematurely. The prevalence of WPW syndrome in the general population is estimated to be 1–3 in 1000 individuals [ 2 ]. WPW syndrome is associated with various SVTs, including AVRT and AF with rapid ventricular response, with AVRT being the most common arrhythmia linked to WPW, and AF occurring in up to 50% of patients with WPW [ 3 , 4 ].…”

Section: Discussionmentioning

confidence: 99%

Pre-Excited Atrial Fibrillation in Wolff-Parkinson-White (WPW) Syndrome: A Case Report and a Review of the Literature

Schiavone,

Filtz,

Gasperetti

et al. 2024

Rev. Cardiovasc. Med.

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Wolff-Parkinson-White (WPW) syndrome is defined by specific electrocardiogram (ECG) changes resulting in ventricular pre-excitation (the so-called WPW pattern), related to the presence of an accessory pathway (AP), combined with recurrent tachyarrhythmias. WPW syndrome is characterized by different supraventricular tachyarrhythmias (SVT), including atrioventricular re-entry tachycardia (AVRT) and atrial fibrillation (AF) with rapid ventricular response, with AVRT being the most common arrhythmia associated with WPW, and AF occurring in up to 50% of patients with WPW. Several mechanisms might be responsible for AF development in the WPW syndrome, and a proper electrocardiographic interpretation is of pivotal importance since misdiagnosing pre-excited AF could lead to the administration of incorrect treatment, potentially inducing ventricular fibrillation (VF). Great awareness of pre-excited AF’s common ECG characteristics as well as associated causes and its treatment is needed to increase diagnostic performance and improve patients’ outcomes. In the present review, starting from a paradigmatic case, we discuss the characteristics of pre-excited AF in the emergency department and its management, focusing on the most common ECG abnormalities, pharmacological and invasive treatment of this rhythm disorder.

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Section: Discussionmentioning

confidence: 99%

Pre-Excited Atrial Fibrillation in Wolff-Parkinson-White (WPW) Syndrome: A Case Report and a Review of the Literature

Schiavone,

Filtz,

Gasperetti

et al. 2024

Rev. Cardiovasc. Med.

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“…Сейчас в медицинском сообществе нет единства в отношении выбора лечения между медикаментозной терапией и катетерными аблациями, особенно это касается возрастной категории детей до 5 лет [26][27][28][29][30][31]. До настоящего времени в отечественной педиатрической кардиологической практике асимптомный синдром WPW не рассматривался как показание к РЧА.…”

Section: обсуждение полученных результатовunclassified

Effects of accessory pathway catheter ablation on left ventricular function in patients with dyssynchrony-induced cardiomyopathy associated with pre-excitation syndrome

Kartofeleva,

Svintsova,

Dzhaffarova

et al. 2024

Vestnik aritmologii

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Aim. To evaluate the effect of radiofrequency ablation (RFA) of accessory pathways on left ventricle (LV) function in patients with Wolff-Parkinson-White (WPW) syndrome and preexitation-induced dyssynchrony cardiomyopathy.Methods. The study included 22 patients with registered preexitation on the ECG and signs of dyssynchronous cardiomyopathy according to echocardiography (Echo): asynchronous movement of interventricular septum, ejection fraction (EF) decrease and/or global longitudinal strain of the left ventricle (GLS LV), heart chamber increase. The average age of patients at the time of RFA of the accessory pathways - 11 years [8;14].Results. A regular normalization of the QRS complex width was observed after RFA (p = 0.0002). To assess reverse LV remodeling, all patients underwent Echo on day 3 after RFA. In patients with an initially reduced LVEF, its increase was noted. In patients with initial dilatation and an increase in LV volume, normalization of these indicators was noted. However, dynamics of LVEF and its volume was not statistically significant in the early postoperative period. According to Speckle-tracking Echo during medical check-up, complete normalization of longitudinal deformation was observed in 13 patients (59%), this indicator improvement - in 7 patients (31.8%). The average GLS LV before RFA was -17.25 [-16.4; -19], after RFA - -21.5 [-19; -24] (p = 0.0001).Conclusion. Reverse remodeling and restoration of LV function after RFA of accessory pathways indicates a cause- and-effect relationship between the accessory pathways functioning and dyssynchronous cardiomyopathy development. Therefore, patients with signs of preexitation-induced dyssynchronous cardiomyopathy are indicated for RFA of accessory pathways, regardless of age and tachycardia paroxysms.

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Herzrhythmusstörungen bei Erwachsenen mit angeborenen Herzfehlern

Franke,

Lüdemann,

Gonzalez Y Gonzalez

2024

Herzschr Elektrophys

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Advancing the science of management of arrhythmic disease in children and adult congenital heart disease patients within the last 25 years

Cited by 10 publications

References 115 publications

Pre-Excited Atrial Fibrillation in Wolff-Parkinson-White (WPW) Syndrome: A Case Report and a Review of the Literature

Pre-Excited Atrial Fibrillation in Wolff-Parkinson-White (WPW) Syndrome: A Case Report and a Review of the Literature

Effects of accessory pathway catheter ablation on left ventricular function in patients with dyssynchrony-induced cardiomyopathy associated with pre-excitation syndrome

Herzrhythmusstörungen bei Erwachsenen mit angeborenen Herzfehlern

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