Advantage of endoscopic submucosal dissection compared with EMR for early gastric cancer

Oka, Shiro; Tanaka, Shinji; Kaneko, Iwao; Mouri, Ritsuo; Hirata, Manabu; Kawamura, T.; Yoshihara, Masaharu; Chayama, Kazuaki

doi:10.1016/j.gie.2006.03.932

Cited by 636 publications

(587 citation statements)

References 24 publications

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“…The outcomes for SM1-GCs that met the expanded criteria and were simply followed up after ESD were equally as good as those for SM-GCs treated by additional surgical resection after ESD. We have reported the usefulness of ESD versus endoscopic mucosal resection for complete resection of EGC [2,21]. ESD makes complete resection possible regardless of tumor size or location.…”

Section: Discussionmentioning

confidence: 99%

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Clinical validity of endoscopic submucosal dissection for submucosal invasive gastric cancer: a single-center study

et al. 2011

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Background The 2010 Japanese Gastric Cancer Association guidelines for the treatment of submucosal invasive gastric cancer (SM-GC) specify size 30 mm or less, differentiated-dominant histology, lack of vessel involvement, and submucosal invasion of less than 500 lm (SM1) as expanded criteria for curative endoscopic resection. Our purpose in this study was to confirm the validity of the expanded indications for curative endoscopic submucosal dissection (ESD) of SM-GC. Methods The study subjects were 173 patients with SM-GC resected by ESD at Hiroshima University Hospital between April 2002 and September 2010, including 99 patients for whom 3-plus years' follow-up information was available. Post-ESD outcomes were compared between cases of SM1-GC that met the expanded ESD criteria, those that did not, and SM2-GC cases.Results Complete resection was achieved for 93.2% of the SM1-GCs that met the expanded criteria. There was neither metastasis to lymph nodes or other organs nor local recurrence among the SM1-GCs. Disease-specific survival did not differ significantly between patients that were simply followed up after ESD and those that were treated by additional surgical resection. Conclusions Our outcome data support the clinical validity of ESD without additional surgical resection for SM1-GCs that meet the expanded criteria.

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Section: Discussionmentioning

confidence: 99%

“…Endoscopic submucosal dissection (ESD) is an established treatment method in Japan that does not rely on snare techniques for the dissection of submucosal tissue and allows en-bloc resection of even large EGCs [2][3][4][5][6]. Moreover, submucosal tissue can be resected with sufficient vertical distance from the muscularis mucosae.…”

Section: Introductionmentioning

confidence: 99%

Clinical validity of endoscopic submucosal dissection for submucosal invasive gastric cancer: a single-center study

et al. 2011

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“…3,[14][15][16] These broad indications for ER can be attributed to the development of ESD, which is superior to EMR due to the higher en bloc and complete resection rates. 3,17 With the enhancements in endoscopic interventions, the interest in iatrogenic ulcers after ER has gradually increased. Iatrogenic ulcers can occasionally cause significant bleeding or abdominal pain, similar to that caused by peptic gastric ulcers.…”

Section: Discussionmentioning

confidence: 99%

Helicobacter pylori Eradication in Patients with an Iatrogenic Ulcer after Endoscopic Resection and Peptic Ulcer

Ahn

et al. 2018

Korean J Helicobacter Up Gastrointest Res

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Background/Aims: We aimed to compare the outcomes and timing of Helicobacter pylori eradication in patients with iatrogenic and peptic ulcers. Materials and Methods: This was a retrospective study of 183 patients treated between 2012 and 2015 with 7-day standard triple therapy after endoscopic resection (ER). The patients were enrolled as the iatrogenic ulcer group and assigned to an early treatment group (n=139, H. pylori eradication initiated 2 days after ER) and a late treatment group (n=44, 8 weeks after ER). During the same period, 152 patients with peptic ulcer were assigned to the peptic ulcer group. Results: Successful H. pylori eradication was achieved in 141 patients (77.0%) in the iatrogenic ulcer group and 114 (75.0%) in the peptic ulcer group (P=0.661). Among the ER patients, the eradication rate was 79.9% (n=111) in the early treatment group and 68.2% (n=30) in the late treatment group (P=0.109). The adverse event rate was significantly higher in the peptic ulcer group than in the iatrogenic ulcer group (13.8% vs. 4.9%, P=0.005). Compliance and adverse events did not significantly differ between the early and late treatment groups. Conclusions: In iatrogenic ulcer, H. pylori eradication can be performed with a relatively lower adverse event rate, regardless of treatment timing, than that in peptic ulcer. (Korean J Helicobacter Up Gastrointest Res 2018;18:30-37)

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“…Comparing these methods, Watanabe et al (14) did not verify a statistical difference in the incidence of perforation, 3.2% for EMR and 4.2% for ESD. However, Oka et al (9) analyzed only nonulcerative lesions found an incidence of 0.5% for EMR and a 9.7% for EDS, which was statistically significant. In this study the rate of gastric perforation was 4,8%, all treated without surgery.…”

Section: Discussionmentioning

confidence: 90%

“…Oka and colleagus (9) verified that the incidence of bleeding during and after EMR was 7.6% and 3.9% for nonulcerative lesions; for ESD, rates were 22.6% and 6.2%, respectively. The bleeding is related with the lesion size and location.…”

Section: Discussionmentioning

confidence: 96%

INITIAL EXPERIENCE OF ENDOSCOPIC SUBMUCOSAL DISSECTION IN BRAZIL TO TREAT EARLY GASTRIC AND ESOPHAGHEAL CANCER: a multi-institutional analysis

Chaves

Moura

Milhomem³

et al. 2013

Arq. Gastroenterol.

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-Objective -This study aimed to evaluate the feasibility and clinicopathological characteristics of early gastric and esophageal cancers treated with endoscopic submucosal dissection (ESD) at five centers in Brazil. (range, 20-150 min). Complications included pneumomediastinum in two (12.5%) patients and stenosis in one (6.2%). Mean duration of follow-up was 8.6 months, with no local recurrence despite the presence of lateral margin compromise. Conclusion -Different centers in Brazil feasibly perform ESD with a high success rate.

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Advantage of endoscopic submucosal dissection compared with EMR for early gastric cancer

Cited by 636 publications

References 24 publications

Clinical validity of endoscopic submucosal dissection for submucosal invasive gastric cancer: a single-center study

Clinical validity of endoscopic submucosal dissection for submucosal invasive gastric cancer: a single-center study

Helicobacter pylori Eradication in Patients with an Iatrogenic Ulcer after Endoscopic Resection and Peptic Ulcer

INITIAL EXPERIENCE OF ENDOSCOPIC SUBMUCOSAL DISSECTION IN BRAZIL TO TREAT EARLY GASTRIC AND ESOPHAGHEAL CANCER: a multi-institutional analysis

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