Advantages of Bacillus-based probiotics in poultry production

Ramlucken, Uraisha; Lalloo, Rajesh; Roets, Yrielle; Moonsamy, Ghaneshree; Rensburg, Christine Jansen van; Thantsha, Mapitsi Silvester

doi:10.1016/j.livsci.2020.104215

Cited by 64 publications

(47 citation statements)

References 193 publications

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“…Thus, the optimum application rate of B. licheniformis used in studies may need further identified. Furthermore, differences in housing environment, broiler breed, administration route of probiotic B. licheniformis as well as the way to establish NE model may influence the outcome of B. licheniformis addition ( Ramlucken et al, 2020 ). However, an improved body weight and FCR of 21–42 days and 1–42 days were seen in the PG and PA group although statistical difference was not reached, indicating that B. licheniformis and enramycin may protect broilers from SNE infection and alleviated growth performance loss caused by SNE to a certain degree.…”

Section: Discussionmentioning

confidence: 99%

Probiotics Bacillus licheniformis Improves Intestinal Health of Subclinical Necrotic Enteritis-Challenged Broilers

et al. 2021

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Necrotic enteritis infection poses a serious threat to poultry production, and there is an urgent need for searching effective antibiotic alternatives to control it with the global ban on in-feed antibiotics. This study was conducted to investigate the effects of dietary Bacillus licheniformis replacing enramycin on the growth performance and intestinal health of subclinical necrotic enteritis (SNE)-challenged broilers. In total, 504 1-day-old Arbor Acres male chickens were selected and subsequently assigned into three treatments, including PC (basal diet + SNE challenge), PA (basal diet extra 10 mg/kg enramycin + SNE challenge), and PG (basal diet extra 3.20 × 109 and 1.60 × 109 CFU B. licheniformis per kg diet during 1–21 days and 22–42 days, respectively + SNE challenge). Results showed that B. licheniformis significantly decreased the intestinal lesion scores and down-regulated the Claudin-3 mRNA levels in jejunum of SNE-infected broilers on day 25, but increased the mucin-2 gene expression in broilers on day 42. In addition, B. licheniformis significantly up-regulated the mRNA levels of TRIF and NF-κB of SNE-challenged broilers compared with the control group on day 25 and TLR-4, TRIF compared with the control and the antibiotic group on day 42. The mRNA expression of growth factors (GLP-2 and TGF-β2) and HSPs (HSP60, HSP70, and HSP90) were up-regulated in B. licheniformis supplementary group on days 25 and 42 compared with group PC. LEfSe analysis showed that the relative abundance of Lachnospiraceae_UCG_010 was enriched in the PG group; nevertheless, Clostridiales_vadinBB60 and Rnminococcaceae_NK4A214 were in PA. PICRUSt analysis found that the metabolism of cofactors and vitamins, amino acid metabolism, and carbohydrate metabolism pathways were enriched, whereas energy metabolism, membrane transport, cell motility, and lipid metabolism were suppressed in B. licheniformis-supplemented groups as compared with the PC control. In conclusion, dietary supplementation of B. licheniformis alleviated the intestinal damage caused by SNE challenge that coincided with modulating intestinal microflora structure and barrier function as well as regulating intestinal mucosal immune responses.

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Section: Discussionmentioning

confidence: 99%

Probiotics Bacillus licheniformis Improves Intestinal Health of Subclinical Necrotic Enteritis-Challenged Broilers

et al. 2021

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“…Bacillus subtilis has been documented to have broadly biochemical effects such as antimicrobial, anti-inflammatory, antioxidant, enzymatic, and immunomodulatory activities in humans and various animals [ 52 , 177 ]. Bacillus subtilis also releases several neuropeptides, such as human-like growth hormone [ 178 , 179 ], parathyroid hormone [ 180 ], and tryptophan [ 181 , 182 , 183 ].…”

Section: Probiotics and The Gut–microbiota–brain Axis In Broilersmentioning

confidence: 99%

“… Modified from the data presented by Grant et al [ 50 ]; Markowiak and Slizewska [ 38 ]; and Ramlucken et al [ 52 ]. 1 Accessed on 12 March 2021.…”

Section: Figurementioning

confidence: 99%

“…B. subtilis, as an ideal multifunctional probiotic bacterium, has been gaining popularity in recent years. It has been used as antibiotic replacement to regulate gut flora, improve growth performance, and enhance immunity and gut health in poultry under various rearing environments and infectious immune challenges [39,[49][50][51][52]. In recent years, a growing body of evidence suggests that detrimental gut microbiota leads to bone loss in humans and various animals.…”

Section: Introductionmentioning

confidence: 99%

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Bacillus subtilis-Based Probiotic Improves Skeletal Health and Immunity in Broiler Chickens Exposed to Heat Stress

Jiang

Yan

et al. 2021

Animals

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The elevation of ambient temperature beyond the thermoneutral zone leads to heat stress, which is a growing health and welfare issue for homeothermic animals aiming to maintain relatively constant reproducibility and survivability. Particularly, global warming over the past decades has resulted in more hot days with more intense, frequent, and long-lasting heat waves, resulting in a global surge in animals suffering from heat stress. Heat stress causes pathophysiological changes in animals, increasing stress sensitivity and immunosuppression, consequently leading to increased intestinal permeability (leaky gut) and related neuroinflammation. Probiotics, as well as prebiotics and synbiotics, have been used to prevent or reduce stress-induced negative effects on physiological and behavioral homeostasis in humans and various animals. The current data indicate dietary supplementation with a Bacillus subtilis-based probiotic has similar functions in poultry. This review highlights the recent findings on the effects of the probiotic Bacillus subtilis on skeletal health of broiler chickens exposed to heat stress. It provides insights to aid in the development of practical strategies for improving health and performance in poultry.

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“…have recently been evaluated, using next generation sequencing. This method could change probiotic exploration, because it can detect other probiotic characteristics, such as bacteriocin production, adhesion-ability, and signaling pathways at the genome level, in addition to safety hazards (Ramlucken et al 2020). Organic acids (acetic, butyric, citric, formic, lactic, propionic, malic, and sorbic acids) and their salts (sodium acetate, sodium butyrate, sodium citrate, sodium formate, sodium lactate, and sodium propionate) have also been used as acidifiers in animal feeds to improve gut health and performance, as well as weight gain, survival, and FCR.…”

Section: Control and Preventionmentioning

confidence: 99%

Feed-Borne Bacillus Cereus: An Emerging Threat to Food Chain Related Hazard, Safety and Pathogenic Potentiality

2021

Int J Vet Sci

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Advantages of Bacillus-based probiotics in poultry production

Cited by 64 publications

References 193 publications

Probiotics Bacillus licheniformis Improves Intestinal Health of Subclinical Necrotic Enteritis-Challenged Broilers

Probiotics Bacillus licheniformis Improves Intestinal Health of Subclinical Necrotic Enteritis-Challenged Broilers

Bacillus subtilis-Based Probiotic Improves Skeletal Health and Immunity in Broiler Chickens Exposed to Heat Stress

Feed-Borne Bacillus Cereus: An Emerging Threat to Food Chain Related Hazard, Safety and Pathogenic Potentiality

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