Adverse Childhood Experiences and Health Indicators in a Young Adult, College Student Sample: Differences by Gender

Grigsby, Timothy J.; Rogers, Christopher J.; Albers, Larisa; Benjamin, Stephanie M.; Lust, Katherine; Eisenberg, Marla E.; Forster, Myriam

doi:10.1007/s12529-020-09913-5

Cited by 55 publications

(50 citation statements)

References 58 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Reward functions underlying addiction are generally thought to involve the ventral tegmental area (VTA) and mesolimbic DA neurons that project from the midbrain VTA to the ventral striatum (VS) or, more specifically, the NAc, which is considered the center of reward learning. It is well-established that ELS increases feelings of dysphoria and anhedonia in humans and leads to an attenuation of behavioral responses to primary and conditioned rewards in animals [200][201][202][203][204][205]. Several investigators have hypothesized that these outcomes may be the result of ELS-induced alterations in NAc function.…”

Section: Effects Of Els On Reward Processing Circuitsmentioning

confidence: 99%

Early Life Stress and Risks for Opioid Misuse: Review of Data Supporting Neurobiological Underpinnings

Oswald

Dunn

Seminowicz

et al. 2021

JPM

View full text Add to dashboard Cite

A robust body of research has shown that traumatic experiences occurring during critical developmental periods of childhood when neuronal plasticity is high increase risks for a spectrum of physical and mental health problems in adulthood, including substance use disorders. However, until recently, relatively few studies had specifically examined the relationships between early life stress (ELS) and opioid use disorder (OUD). Associations with opioid use initiation, injection drug use, overdose, and poor treatment outcome have now been demonstrated. In rodents, ELS has also been shown to increase the euphoric and decrease antinociceptive effects of opioids, but little is known about these processes in humans or about the neurobiological mechanisms that may underlie these relationships. This review aims to establish a theoretical model that highlights the mechanisms by which ELS may alter opioid sensitivity, thereby contributing to future risks for OUD. Alterations induced by ELS in mesocorticolimbic brain circuits, and endogenous opioid and dopamine neurotransmitter systems are described. The limited but provocative evidence linking these alterations with opioid sensitivity and risks for OUD is presented. Overall, the findings suggest that better understanding of these mechanisms holds promise for reducing vulnerability, improving prevention strategies, and prescribing guidelines for high-risk individuals.

show abstract

Section: Effects Of Els On Reward Processing Circuitsmentioning

confidence: 99%

Early Life Stress and Risks for Opioid Misuse: Review of Data Supporting Neurobiological Underpinnings

Oswald

Dunn

Seminowicz

et al. 2021

JPM

View full text Add to dashboard Cite

show abstract

“…Given the importance of childhood trauma in the prognosis and illness course of patients with SZ and BD (Nemeroff 2016;Teicher et al 2016;Pruessner et al 2017), evidence-based interventions addressing long-term effects of trauma experiences are needed (Alameda et al 2020). Although there was no difference in body mass index between groups in the current study, a history of childhood trauma has been associated with higher body mass index and C-reactive protein (CRP) (Aas et al 2017;Moraes et al 2017) and poorer physical health behaviour in general (Grigsby et al 2020) demonstrating the need to improve physical health in individuals with trauma experiences.…”

Section: Discussionmentioning

confidence: 65%

Physical activity and childhood trauma experiences in patients with schizophrenia or bipolar disorders

Aas

Ueland

Mørch

et al. 2021

The World Journal of Biological Psychiatry

View full text Add to dashboard Cite

Background: Physical activity promotes resilience and reduces stress. Here we aimed to clarify the impact of physical activity and childhood trauma experiences on current mood and cognitive function in patients with schizophrenia (SZ) or bipolar disorders (BD). Methods: Three-hundred-and-six patients with DSM-IV schizophrenia (SZ) or bipolar disorder (BD) were included in the study. Diagnoses were assessed using the Structured Clinical Interview for DSM-IV Axis I disorders (SCID-I). Physical activity was measured as hours spent on any regular physical activity per week. All patients underwent a neuropsychological test battery. History of Childhood trauma was assessed using the Childhood Trauma Questionnaire and mood symptoms were assessed with the Inventory of Depressive Symptoms. Results: Patients with childhood trauma who were physically inactive (˂90 min per week) had the most severe clinical profile, characterised by the highest depressive symptoms (p ˂ 0.001) and lowest performance on working memory tasks (p ˂ 0.001). Among patients with childhood trauma, those who were physically active (!90 min per week) had better working memory performance than physically inactive patients (p ¼ 0.02). Discussion: A history of childhood trauma was associated with poorer working memory and more depressive symptoms only in patients who were physically inactive, suggesting a possible protective factor of physical activity in severe mental disorder.

show abstract

“…A large body of evidence supports the adverse effects of violence exposure in childhood violence on mental health in men and women; for example, experiences of child abuse in the home have been associated with anxiety disorders, depression, posttraumatic stress disorder (PTSD), substance use, and self-harming behaviors as adults ( Cater et al, 2015 ; Copeland et al, 2018 ; Grigsby et al, 2020 ). Multiple studies demonstrate that experiencing IPV as a target is associated with depression, anxiety, PTSD, and suicide ideation in men ( Bates, 2020a ; Hines & Douglas, 2015 ; Machado et al, 2017 ; Próspero, 2007 ; Randle & Graham, 2011 ).…”

Section: Literature Reviewmentioning

confidence: 99%

The Mental Health Effects of Cumulative Lifetime Violence in Men: Disruptions in the Capacity to Connect with Others and Finding Ways to Reengage

Taylor

O’Donnell

Wuest

et al. 2021

Global Qualitative Nursing Research

View full text Add to dashboard Cite

We report qualitative findings of our Men’s Violence Gender and Health Study, a multiple method study using a sequential design in which we explored the mental health manifestations of cumulative lifetime violence in men. Survey results revealed that higher cumulative lifetime violence scores were significantly associated with higher scores on depression, post-traumatic stress disorder, and anxiety in a community sample of men ( n = 685) living in Eastern Canada. To obtain a deeper understanding of men’s scores, we used an interpretive description approach to analyze data derived from 32 participant interviews. The main mental health manifestation of cumulative lifetime violence is perceptual interference, a sense of being disconnected or detached from others. This is managed by rectifying detachment, a process that includes efforts to gain connections with others. Findings suggest mental health needs in men with cumulative lifetime violence contradict gender role expectations to be stoic. Implications for nurses are explored.

show abstract

Adverse Childhood Experiences and Health Indicators in a Young Adult, College Student Sample: Differences by Gender

Cited by 55 publications

References 58 publications

Early Life Stress and Risks for Opioid Misuse: Review of Data Supporting Neurobiological Underpinnings

Early Life Stress and Risks for Opioid Misuse: Review of Data Supporting Neurobiological Underpinnings

Physical activity and childhood trauma experiences in patients with schizophrenia or bipolar disorders

The Mental Health Effects of Cumulative Lifetime Violence in Men: Disruptions in the Capacity to Connect with Others and Finding Ways to Reengage

Contact Info

Product

Resources

About