“…Several studies have shown that smoking is closely associated with education, alcohol intake, and social support (Donovan and Jessor, 1985 ; Shiffman et al, 1994 ; Ary et al, 1999 ; Haustein, 2006 ; Gilman et al, 2008 ; Jackson et al, 2010 ). Other reports suggest that these factors are likely associated with childhood adversity and ADS later in life (Kauhanen et al, 2011 ; Lemos et al, 2012 ; Kim et al, 2013 ; Mersky et al, 2013 ; Campbell et al, 2016 ; Nurius et al, 2016 ). Consequently, several studies have indicated that education, alcohol intake, and social support mediate the association between childhood adversity and ADS in adulthood (Nurius et al, 2015 ; Openshaw et al, 2015 ; Shevlin et al, 2015 ; Lê-Scherban et al, 2016 ; Muller, 2016 ; Ni et al, 2016 ; Sheikh et al, 2016a , b ; Tani et al, 2016 ; Korhonen et al, 2017 ; Kwon and Park, 2017 ; Lee et al, 2017 ; Markkula et al, 2017 ; Wielaard et al, 2017 ) and suggested that these are important mediator-response confounding factors that must be included in analytical models in order to assess the indirect effect of childhood adversity on ADS in adulthood via smoking.…”