Adverse drug reaction reporting by community pharmacists in the Greater Accra Region of Ghana, 2016

Osei, Johnson Y.; Nortey, Priscillia; Bandoh, Delia Akosua; Kenu, Ernest; Lartey, Adolphina A. Addo

doi:10.4314/gmj.v55i1.3

Cited by 5 publications

(2 citation statements)

References 15 publications

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“…Under-reporting in this Municipality is consistent with previous studies that showed gaps in reporting rates of 79.0% among physicians and 84.0% among Pharmacists in the Greater Accra region [ 13 , 14 ]. We observed a higher gap in reporting rate of 97.2%.…”

Section: Discussionsupporting

confidence: 90%

“…In the Greater Accra Region of Ghana, research on under-reporting of ADRs discovered that only 21% of physicians reported ADRs in 2011, although 59.5% had encountered a patient with an ADR [ 13 ]. A similar study among community pharmacists reported that only 16% of those who had seen a patient with a suspected ADR in 2015 reported it [ 14 ].…”

Section: Introductionmentioning

confidence: 99%

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Under-reporting of adverse drug reactions: Surveillance system evaluation in Ho Municipality of the Volta Region, Ghana

Buabeng,

Dsane-Aidoo,

Asamoah

et al. 2023

PLoS ONE

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Background Adverse Drug Reactions (ADRs) can occur with all medicines even after successful extensive clinical trials. ADRs result in more than 10% of hospital admissions worldwide. In Ghana, there has been an increase of 13 to 126 ADR reports per million population from 2012 to 2018. ADR Surveillance System (ADRSS) also known as pharmacovigilance has been put in place by the Ghana Food and Drugs Authority (FDA) to collect and manage suspected ADR reports and communicate safety issues to healthcare professionals and the general public. The ADRSS in Ho Municipality was evaluated to assess the extent of reporting of ADRs and the system’s attributes; determine its usefulness, and assess if the ADRSS is achieving its objectives. Methods We evaluated the ADRSS of the Ho Municipality from January 2015 to December 2019. Quantitative data were collected through interviews and review of records. We adapted the updated CDC guidelines to develop interview guides and a checklist for data collection. Attributes reviewed included simplicity, data quality, acceptability, representativeness, timeliness, sensitivity, predictive value positive and stability. Results We found a total of 1,237 suspected ADR during the period, of which only 36 (3%) were reported by healthcare professionals in the Ho Municipality to the National Pharmacovigilance Centre (NPC). Only 43.9% of health staff interviewed were familiar with the ADRSS and its reporting channel. Staff who could mention at least one objective of the ADRSS were 34.2%, and 12.2% knew the timelines for reporting ADR. Reports took a median time of 41 (IQR = 25, 81) days from reporter to NPC. Reports sent on time constituted 37.5%. Fully completed case forms constituted 77.1% and the predictive value positive (PVP) was 20%. About 53% of ADRs were reported for female patients. Up to 88.9% of ADRs were classified as drug related. Anti-tuberculosis agents and other antibiotics constituted (40.6%) and (18.8%) of all reports. The ADRSS was not integrated into the disease surveillance and response system of Ghana’s Health Service and so was not flexible to changes. A dedicated ADR surveillance officer in regions helped with the system’s stability. Data from Ghana feeds into a WHO database for global decision making. Conclusions There was under-reporting of ADRs in the Ho Municipality from January 2015 to December 2019. The ADR surveillance system was simple, stable, acceptable, representative, had a strong PVP but was not flexible or timely. The ADRSS was found useful and partially met its objectives.

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Section: Discussionsupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

Under-reporting of adverse drug reactions: Surveillance system evaluation in Ho Municipality of the Volta Region, Ghana

Buabeng,

Dsane-Aidoo,

Asamoah

et al. 2023

PLoS ONE

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Pharmaceutical Waste Disposal Practices in Volta Regional Pharmacies

Essilfie‐Essel,

Wiafe,

Mensah

et al. 2024

Environmental Quality Mgmt

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Appropriate disposal of pharmaceutical waste (PCW) is necessary to avoid potential risks and harm to the environment. Globally, there is extensive literature on the disposal practices of households and hospitals. However, literature on the disposal practices by pharmacies in Ghana is scanty, particularly in the study setting, the Volta Region of Ghana. This study (i) investigated the methods of PCW disposal, (ii) assessed the awareness and compliance of pharmacies with the disposal guidelines of the Food and Drugs Authority (FDA), and (iii) evaluated the impact of the years of existence and category of community pharmacies on compliance with FDA guidelines. A prospective cross‐sectional study design was used. Trained data collectors sampled all 81 registered pharmacies in the Volta Region. Questionnaires used were adapted from tools used in previous published studies. Descriptive data were presented in tables, and associations were measured with chi‐square tests. Statistical tests were set at 95% confidence intervals and p values set at 5% significance. Seventy‐four pharmacists responded to the questionnaire. Disposal through the FDA was the commonest method for all categories of dosage forms surveyed. The second most common method of disposal for all categories of dosage forms was by returning to parent companies. The majority of pharmacists (93.2%) were aware of the FDA (Ghana) disposal guidelines. However, 35.1% of pharmacies complied, 45.9% did not comply, and 2.7% were partially compliant. The type or category of pharmacy was not associated with compliance with disposal guidelines (p value = 0.889). However, the years of existence of pharmacies were associated with compliance with disposal guidelines (p value = 0.008). Although pharmacists in the Volta Region are aware of the PCW disposal guidelines of the FDA (Ghana), regardless of their years of experience and the type/category of community pharmacy they operate, they do not comply with these guidelines.

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Adverse drug reaction reporting by healthcare providers in sub-Saharan Africa: A scoping review of the challenges faced and the strategies to address the challenges

Moyo,

Mangoya

et al. 2023

International Journal of Africa Nursing Sciences

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Adverse drug reaction reporting by community pharmacists in the Greater Accra Region of Ghana, 2016

Cited by 5 publications

References 15 publications

Under-reporting of adverse drug reactions: Surveillance system evaluation in Ho Municipality of the Volta Region, Ghana

Under-reporting of adverse drug reactions: Surveillance system evaluation in Ho Municipality of the Volta Region, Ghana

Pharmaceutical Waste Disposal Practices in Volta Regional Pharmacies

Adverse drug reaction reporting by healthcare providers in sub-Saharan Africa: A scoping review of the challenges faced and the strategies to address the challenges

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