Adverse Drug Reactions for CAM and Conventional Drugs Detected in a Network of Physicians Certified to Prescribe CAM Drugs

Tabali, Manuela; Ostermann, Thomas; Jeschke, Elke; Witt, Claudia M.; Matthes, Harald

doi:10.18553/jmcp.2012.18.6.427

Cited by 16 publications

(13 citation statements)

References 34 publications

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“…Nonetheless, approximately 1% of the COTC users (n = 8) had an adverse reaction for which they sought medical treatment, giving a rough estimate of more severe adverse events in the population. Although a previous study conducted on emergency room patients in Hong Kong reported that rashes and systemic allergic reactions comprised over 90% of the adverse events [35,45], our study found that these conditions only represented about half of the adverse events in the general population while dizziness, nausea, vomiting, and gastro-intestinal problems comprised most of the remaining cases. Adverse events such as sleep disturbances, exacerbation of existing illnesses, and heart-related problems that were previously unreported in the COTC literature were also shown in this study.…”

Section: Discussioncontrasting

confidence: 81%

“…These studies may present a highly biased picture of the COTC-related harms in the general population, since only severe adverse events are likely to be treated in emergency rooms. Internationally, studies on complementary medicine have noted relatively low levels of adverse drug reactions as compared to conventional Western drugs [33-35]. However, these studies of adverse events were typically conducted on patients who were prescribed complementary and alternative medicine by licensed practitioners and not self-medicating.…”

Section: Introductionmentioning

confidence: 99%

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Acute adverse events from over-the-counter Chinese herbal medicines: a population-based survey of Hong Kong Chinese

Kim

Kwong

Chung

et al. 2013

BMC Complement Altern Med

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BackgroundAlthough over-the-counter traditional Chinese herbal medicine (COTC) is commonly used to treat everyday illness in many parts of the world, no population-based study has been done to examine the prevalence and factors associated with COTC-related adverse events.MethodsA cross-sectional telephone survey was conducted among Hong Kong Chinese adults in 2011 (n = 1100) with informed verbal consent. Stepwise logistic regression of demographic, attitudinal and behavioral variables was used to determine factors associated with past-year adverse events.ResultsOf study respondents, 71.7% (789/1100) reported past-year COTC use and 2.3% (25/1100) reported at least one COTC-related adverse event in the past year. Of the 27 adverse events cases reported among COTC users, the most common were allergic reactions (n = 11) dizziness (n = 5), and gastro-intestinal problems (n = 4). Pills/capsules were the dosage form that caused the highest proportion of adverse events (n = 10), followed by plasters (n = 7), creams/ointments (n = 5), and ingestible powders (n = 2).Although COTC users reporting adverse events were more likely to report greater practices to avoid adverse events (OR = 6.47; 95% CI: 1.38-30.3); they were also more likely to possess lower education levels (OR = 9.64, 95% CI: 2.20-42.3) and to have received COTC information from non-reliable, mass-media information sources such as magazines (OR = 3.32; 95% CI: 1.01-8.50) or television (OR = 2.93; 95% CI: 1.03-10.7). Package labels were also felt to be unclear by 42.9% of COTC users. A large proportion of COTC users demonstrated low levels of COTC-related knowledge, while the main impediment to greater information-seeking was the belief that reliable COTC information is not obtainable from Western health professionals.ConclusionsDespite global movements toward more stringent complementary medicine regulation, the limited accessibility of reliable information and widespread misperceptions among consumers present major challenges for the safe use of complementary medicine.

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Section: Discussioncontrasting

confidence: 81%

Section: Introductionmentioning

confidence: 99%

Acute adverse events from over-the-counter Chinese herbal medicines: a population-based survey of Hong Kong Chinese

Kim

Kwong

Chung

et al. 2013

BMC Complement Altern Med

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“…Given the popularity of CHA, and evidence indicating CHA are primarily used to supplement rather than replace conventional health care (5–7), disclosure of CHA use to health-care providers is crucial for ensuring coordination of care (8), for minimizing any potential adverse reactions between CHA and conventional treatments (9, 10), and for improving adherence to treatment (e.g., 11). Disclosing CHA use can also facilitate better integration of CHA into both conventional care treatments and self-care.…”

mentioning

confidence: 99%

Implicit Reasons for Disclosure of the Use of Complementary Health Approaches (CHA): a Consumer Commitment Perspective

2017

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Background Disclosure of the use of complementary health approaches (CHA) is an important yet understudied health behaviour with important implications for patient care. Yet research into disclosure of CHA has been atheoretical and neglected the role of health beliefs. Purpose Using a consumer commitment model of CHA use as a guiding conceptual framework, the current study tests the hypotheses that perceived positive CHA outcomes (utilitarian values) and positive CHA beliefs (symbolic values) are associated with disclosure of CHA to conventional-care providers in a nationally representative US sample. Methods From a sample of 33,594 with CHA use information from the 2012 National Health Interview Survey (NHIS), a subsample of 7,348 who used CHA within the past 12 months was analysed. The 2012 NHIS is a cross-sectional survey of the non-institutionalized US adult population, which includes the most recent nationally representative CHA use data. Results The 63.2 % who disclosed CHA use were older, less educated, and had visited a health-care provider in the past year. Weighted logistic regression analyses controlling for demographic variables revealed that those who disclosed were more likely to report experiencing positive psychological (improved coping and well-being) and physical outcomes (better sleep, improved health) from CHA, and hold positive CHA-related beliefs. Conclusions CHA users who perceive physical and psychological benefits from CHA use, and who hold positive attitudes towards CHA are more likely to disclose their CHA use. Findings support the relevance of a consumer commitment perspective for understanding CHA disclosure, and suggest CHA disclosure as an important proactive health behaviour that warrants further attention.

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“…Physicians were required to give their informed consent to participate in the EvaMed Network and to report all detected serious ADRs (definition provided below “data collection and classification of ADRs”) to the EvaMed Network. A total of 38 physicians from 12 of the 16 federal German states finally agreed to participate in EvaMed, covering 6.1% of the overall primary care physicians of the GAÄD [17]. They all had practised for at least five years in primary care in addition to completing training in anthroposophic medicine.…”

Section: Methodsmentioning

confidence: 99%

Depression, Comorbidities, and Prescriptions of Antidepressants in a German Network of GPs and Specialists with Subspecialisation in Anthroposophic Medicine: A Longitudinal Observational Study

Jeschke

Ostermann

Vollmar

et al. 2012

Evidence-Based Complementary and Alternative Medicine

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Background. Depression is a major reason for counselling in primary care. Our study aims at evaluating pharmacological treatment strategies among physicians specialised in anthroposophic medicine (AM). Methods. From 2004 to 2008, twenty-two German primary care AM-physicians participated in this prospective, multicentre observational study. Multiple logistic regression was used to determine factors associated with a prescription of any antidepressant medication. Results. A total of 2444 patients with depression were included (mean age: 49.1 years (SD: 15.4); 77.3% female). 2645 prescriptions of antidepressants for 833 patients were reported. Phytotherapeutic preparations from Hypericum perforatum were the most frequently prescribed antidepressants over all (44.6% of all antidepressants), followed by amitriptyline (16.1%). The likelihood of receiving an antidepressant medication did not depend on comorbidity after controlling for age, gender, physician specialisation, and type of depression (adjusted OR (AOR) = 1.01; CI: 0.81–1.26). Patients who had cancer were significantly less likely to be prescribed an antidepressant medication than those who had no cancer (AOR = 0.75; CI: 0.57–0.97). Conclusion. This study provides a comprehensive analysis of everyday practice for the treatment of depression in AM -physicians. Further analysis regarding the occurrence of critical combinations is of high interest to health services research.

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Adverse Drug Reactions for CAM and Conventional Drugs Detected in a Network of Physicians Certified to Prescribe CAM Drugs

Cited by 16 publications

References 34 publications

Acute adverse events from over-the-counter Chinese herbal medicines: a population-based survey of Hong Kong Chinese

Acute adverse events from over-the-counter Chinese herbal medicines: a population-based survey of Hong Kong Chinese

Implicit Reasons for Disclosure of the Use of Complementary Health Approaches (CHA): a Consumer Commitment Perspective

Depression, Comorbidities, and Prescriptions of Antidepressants in a German Network of GPs and Specialists with Subspecialisation in Anthroposophic Medicine: A Longitudinal Observational Study

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