Adverse Drug Reactions in Children with Congenital Heart Disease: A Scoping Review

Toni, Esmaeel; Ayatollahi, Haleh; Abbaszadeh, Reza; Fotuhi Siahpirani, Alireza

doi:10.1007/s40272-024-00644-8

Pediatr Drugs

2024

DOI: 10.1007/s40272-024-00644-8

|View full text |Cite

Adverse Drug Reactions in Children with Congenital Heart Disease: A Scoping Review

Esmaeel Toni,

Haleh Ayatollahi,

Reza Abbaszadeh

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

References 126 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Addressing Drug-Related Side Effects in Children With Congenital Heart Disease: A Policy Brief

Toni,

Ayatollahi

2024

Global Pediatric Health

View full text Add to dashboard Cite

Addressing Drug-Related Side Effects in Children With Congenital Heart Disease: A Policy Brief

Toni,

Ayatollahi

2024

Global Pediatric Health

View full text Add to dashboard Cite

The Utilization of Acetaminophen for Managing PGE1-Induced Fever in Neonates with Critical Congenital Heart Disease

Kaya,

Akduman,

Dilli

et al. 2024

Children

View full text Add to dashboard Cite

Introduction: We aimed to retrospectively evaluate the use of acetaminophen, which may be a risk factor for the ductal canal, in the treatment of fever due to prostaglandin E1 (PGE1) infusion in newborns with critical congenital heart disease (CCHD). Methods: The study included newborns who were followed-up in our neonatal intensive care unit with the diagnosis of critical congenital heart disease, developed fever due to PGE1 infusion and had acetaminophen administered for antipyretic treatment. The patent ductus arteriosus diameters of the patients were evaluated by echocardiographic imaging before intravenous acetaminophen treatment and at the end of the day of acetaminophen treatment. Results: PGE1 fever was observed in 10 (6%) of 156 infants with ductus-dependent congenital heart disease. Intravenous acetaminophen treatment administered as an antipyretic in these infants did not cause the narrowing or closure of the ductal canal diameter, which would lead to clinical decompensation if it was closed, and the patients remained hemodynamically stable until surgery. Conclusions: It can be considered that controlled and rapidly administered intravenous acetaminophen therapy in the management of fever in neonates with congenital heart disease who develop fever as a side effect of high-dose intravenous PGE1 infusion therapy (≥0.3 mcg/kg/min) may prevent hemodynamic decompensation in these critically ill infants, and as a secondary outcome, it can be speculated that avoiding rapid daily increases in PGE1 maintenance infusion doses may be necessary to limit the number of paracetamol administrations in these infants.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Adverse Drug Reactions in Children with Congenital Heart Disease: A Scoping Review

Cited by 2 publications

References 126 publications

Addressing Drug-Related Side Effects in Children With Congenital Heart Disease: A Policy Brief

Addressing Drug-Related Side Effects in Children With Congenital Heart Disease: A Policy Brief

The Utilization of Acetaminophen for Managing PGE1-Induced Fever in Neonates with Critical Congenital Heart Disease

Contact Info

Product

Resources

About