Adverse Effect of Early High-Dose Adrenaline on Outcome of Ventricular Fibrillation

Marwick, T.; Siskind, Victor; Case, Colin; Woodhouse, S.P.

doi:10.1016/s0140-6736(88)90003-7

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Medications In Cardiac Arrest and Bradycardia1

Human Studies -Standard Dose V High Dose1

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2010

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Cited by 36 publications

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“…Evidence extrapolated from adult prehospital or in-hospital studies, including 9 LOE 1 randomized trials, 494–502 3 LOE 2 trials, 503–505 and 3 LOE 3 studies, 506–508 showed no improvement in survival to hospital discharge or neurologic outcome when doses >1 mg of epinephrine were given.…”

Section: Medications In Cardiac Arrest and Bradycardiamentioning

confidence: 99%

Part 10: Pediatric Basic and Advanced Life Support

Kleinman

Caen

Chameides³

et al. 2010

Circulation

184

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Note From the Writing Group: Throughout this article, the reader will notice combinations of superscripted letters and numbers (eg, “Family Presence During ResuscitationPeds-003”). These callouts are hyperlinked to evidence-based worksheets, which were used in the development of this article. An appendix of worksheets, applicable to this article, is located at the end of the text. The worksheets are available in PDF format and are open access.

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