Adverse effects of obesity on lipid and lipoprotein levels in the patients with non-insulin dependent diabetes in the young

Kawahara, Reiko; Amemiya, Teiko; Yoshino, Masayo; Komori, Tomonori; Shibata, Naomi; Hirata, Yoshihiro

doi:10.1016/0168-8227(90)90168-s

Cited by 2 publications

(2 citation statements)

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“…In a report by the WHO published in 2010, obesity and overweight have been identified as the most important contributors to the rising trend of type 2 DM [ 44 ]. Moreover, numerous other studies have also suggested obesity to be the most important risk factor for type 2 DM [ 45 – 47 ]. Therefore, it seems that by the continuous control of the blood lipids and preventive measures to stop its increasing rate, the prevalence of type 2 DM and hence its chronic complications, especially cardiovascular disease, can be reduced in society.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Cardiovascular Disease in Patients with Type 2 Diabetes Mellitus in Iran: A Systematic Review and Meta-Analysis

Kazeminia

Salari

Mohammadi

2020

Journal of Diabetes Research

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Background. Type 2 diabetes mellitus (DM) is the most common type of DM and accounts for 90% of the cases. One of the most important complications of type 2 DM is cardiovascular complications, which are the most common cause of mortality in patients with DM. Various studies have reported different incidence rates of cardiovascular disease in patients with type 2 DM. However, no comprehensive review of previous studies has been done. This study is aimed at determining the prevalence of cardiovascular disease in patients with type 2 diabetes mellitus in Iran with a systematic review and meta-analysis. Methods. In this review, studies were first extracted searching domestic and international databases including SID, MagIran, IranMedex, IranDoc, Cochrane, Embase, ScienceDirect, Scopus, PubMed, and Web of Science (ISI), published between 2001 and September 2019. The random effects model was adopted for the analysis, and heterogeneity of the extracted studies was investigated with the I2 index. The data collected from the extracted studies were analyzed using a comprehensive meta-analysis (Version 2) software. Results. The prevalence of cardiovascular disease in patients with type 2 DM in Iran in 17 studies with a sample size of 9656 was 37.4% (95% CI: 31.4-43.8). Based on meta-regression, there was a significant difference on the effect of year of conducting the study and sample size with the prevalence of cardiovascular disease in patients with type 2 DM in Iran (p≤0.001). Conclusion. The results of this study indicated that there was a high prevalence rate of cardiovascular disease in patients with type 2 DM in Iran. Therefore, appropriate strategies should be taken to improve this situation and trace and supervise it at all levels, providing feedback to hospitals.

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Section: Discussionmentioning

confidence: 99%

Prevalence of Cardiovascular Disease in Patients with Type 2 Diabetes Mellitus in Iran: A Systematic Review and Meta-Analysis

Kazeminia

Salari

Mohammadi

2020

Journal of Diabetes Research

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“…A meta-analysis revealed that among adults, elevated NO 2 , SO 2 , and O 3 increases the risk of obesity by 13%, 4%, and 7%, respectively [97]. Obesity often leads to an increase in blood lipid levels [98,99]. For example, the study of Guo et al showed that compared with normal weight subjects, overweight and obese subjects had significantly higher LDL-C and lower HDL-C, while abdominal obesity was associated with higher TG after multiple-factor adjustment [99].…”

Section: Metabolic Dysfunction Diseasesmentioning

confidence: 99%

Association between Air Pollution and Lipid Profiles

Zhang,

Shi,

et al. 2023

Toxics

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Dyslipidemia is a critical factor in the development of atherosclerosis and consequent cardiovascular disease. Numerous pieces of evidence demonstrate the association between air pollution and abnormal blood lipids. Although the results of epidemiological studies on the link between air pollution and blood lipids are unsettled due to different research methods and conditions, most of them corroborate the harmful effects of air pollution on blood lipids. Mechanism studies have revealed that air pollution may affect blood lipids via oxidative stress, inflammation, insulin resistance, mitochondrial dysfunction, and hypothalamic hormone and epigenetic changes. Moreover, there is a risk of metabolic diseases associated with air pollution, including fatty liver disease, diabetes mellitus, and obesity, which are often accompanied by dyslipidemia. Therefore, it is biologically plausible that air pollution affects blood lipids. The overall evidence supports that air pollution has a deleterious effect on blood lipid health. However, further research into susceptibility, indoor air pollution, and gaseous pollutants is required, and the issue of assessing the effects of mixtures of air pollutants remains an obstacle for the future.

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Adverse effects of obesity on lipid and lipoprotein levels in the patients with non-insulin dependent diabetes in the young

Cited by 2 publications

References 4 publications

Prevalence of Cardiovascular Disease in Patients with Type 2 Diabetes Mellitus in Iran: A Systematic Review and Meta-Analysis

Prevalence of Cardiovascular Disease in Patients with Type 2 Diabetes Mellitus in Iran: A Systematic Review and Meta-Analysis

Association between Air Pollution and Lipid Profiles

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