Adverse events and preventive measures related to COVID-19 vaccines

Abstract

The coronavirus disease 2019 (COVID-19) vaccines are categorized according to the manufacturing technique, including mRNA vaccines and adenovirus vector vaccines. According to previous studies, the reported efficacy of the COVID-19 vaccine is excellent regardless of the type of vaccine, and the majority of studies have shown similar results for safety. Most of the adverse reactions after vaccination were mild or moderate grade, and severe reactions were reported in a very small proportion. However, the adverse reactions that might occur after nationwide vaccinations can contribute to crowding of emergency departments, and this can further lead to significant obstacles to providing necessary treatment for life-threatening conditions. Therefore, as emergency physicians, we would like to present some concerns and suggestions to prevent these predictable problems.

Post-vaccination incidence and side effects of COVID-19 in a cohort of Brazilian healthcare professionals: an internet-based survey

“…Additionally, they may cause systemic symptoms, such as headache, fatigue, malaise, nausea, and fever, which are similar to symptoms of some infectious diseases, including COVID-19. (8) Most of the major vaccine reactions are compulsorily notified; however, minor reactions, such as headache and myalgia, are usually underreported. (3,6,9) To the best of my knowledge, this is the largest study published about adverse effects of CoronaVac-Butantan/Sinovac vaccine.…”