Adverse events associated with nonablative cutaneous visible and infrared laser treatment

Handley, J.

doi:10.1016/j.jaad.2006.03.029

Cited by 56 publications

(70 citation statements)

References 19 publications

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“…4,7,15 The overall treatment course is often prolonged, costly, and sometimes impractical, which can lead to patient dissatisfaction and abandonment of the treatment. 2,9,11,16 Risks of treatment include scarring, 2 permanent hypopigmentation, 15,16 and the possibility of incomplete tattoo removal. 13 For these reasons, laser tattoo removal frustrates patients and challenges clinicians.…”

Section: Introductionmentioning

confidence: 99%

Optimal tattoo removal in a single laser session based on the method of repeated exposures

Kossida

Rigopoulos

Katsambas

et al. 2012

Journal of the American Academy of Dermatology

104

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Section: Introductionmentioning

confidence: 99%

Optimal tattoo removal in a single laser session based on the method of repeated exposures

Kossida

Rigopoulos

Katsambas

et al. 2012

Journal of the American Academy of Dermatology

104

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“…At higher temperatures, thermal coagulation, collagen hyalinization, and changes in optical properties, such as increased scattering or birefringence, may be observed. [15][16][17] Several authors have contributed to numerical simulations of optical-thermal response of tissues and models of the damage process. These are largely built on the original works of Mainster 18 and Takata, 19,20 with many authors contributing through the addition of increased fidelity.…”

Section: Introductionmentioning

confidence: 99%

Infrared skin damage thresholds from 1319-nm continuous-wave laser exposures

Oliver

Vincelette²,

Noojin³

et al. 2013

J. Biomed. Opt

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Abstract. A series of experiments were conducted in vivo using Yucatan miniature pigs (Sus scrofa domestica) to determine thermal damage thresholds to the skin from 1319-nm continuous-wave Nd:YAG laser irradiation. Experiments employed exposure durations of 0.25, 1.0, 2.5, and 10 s and beam diameters of ∼0.6 and 1 cm. Thermal imagery data provided a time-dependent surface temperature response from the laser. A damage endpoint of fifty percent probability of a minimally visible effect was used to determine threshold for damage at 1 and 24 h postexposure. Predicted thermal response and damage thresholds are compared with a numerical model of opticalthermal interaction. Resultant trends with respect to exposure duration and beam diameter are compared with current standardized exposure limits for laser safety. Mathematical modeling agreed well with experimental data, predicting that though laser safety standards are sufficient for exposures <10 s, they may become less safe for very long exposures. © The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

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“…1, region 2), which should account for the required multiple therapeutic sessions. 1,14,15 Besides, it was also found that higher laser energy could lead to higher risk of side e®ects such as blisters and bleeding (Table 1).…”

Section: Discussionmentioning

confidence: 99%

“…1,14,15 For large, deep and complex tattoos, much more sessions and increased laser intensity are recommended to compensate the energy loss caused by tissue scattering and absorption, 16 yet which can cause many side e®ects such as purpura, blistering and damage to the surrounding tissues. 15,16 The skin optical clearing method, by introducing optical clearing agent (OCA) which is of high refractive index, hyperosmosis and biocompatibility into skin, could reduce skin scattering, [17][18][19] and has been reported to be e®ective to improve laser tattoo removal. Prior application of the OCA (PPG:PEG) has been shown to be e®ective in improving the outcome of tattoo removal by Q-switched 532 and 694 nm laser treatment.…”

Section: Introductionmentioning

confidence: 99%

Quantitative evaluation of enhanced laser tattoo removal by skin optical clearing

Liu

Shi

Chen

et al. 2015

J. Innov. Opt. Health Sci.

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Lasers have been widely used for tattoo removal, but the limited light penetration depth caused by high skin scattering property restricts the therapeutic outcome of deep tattoo. Skin optical clearing method, by introducing optical clearing agent (OCA) into skin, has shown some improvement in the e®ect of laser tattoo removal. In this study, the enhanced laser tattoo removal has been quantitatively assessed. OCA was applied to the skin of tattoo animal model and Q-switched Nd:YAG laser (1064 nm) irradiation was used to remove the tattoo. The skin evaluation instrument (Mexameter probe, MPA580) was applied to measure the content of tattoo pigment before and after laser treatment, and then the clearance rate of pigment was calculated. Further, Monte Carlo (MC) method was utilized to simulate the e®ect of skin optical clearing on light transmission in tattoo skin model. By comparing the pigment change of tattoo areas respectively treated with OCA plus laser and single laser, it was found that pigment clearance of the former tattoo area was increased by 1.5-fold. Further, the MC simulation veri¯ed that the reduced light scattering in skin could increase the e®ective dose of luminous°ux reaching to the deep tattoo regions. It can be concluded from both experiment and theoretical This is an Open Access article published by World Scienti¯c Publishing Company. It is distributed under the terms of the Creative Commons Attribution 3.0 (CC-BY) License. Further distribution of this work is permitted, provided the original work is properly cited. k Corresponding Authors. Vol. 8, No. 3 (2015) 1541007 (8 pages simulations that skin optical clearing technique could improve the outcome of laser tattoo removal, which should be bene¯cial for clinical laser tattoo removal and other laser pigment elimination. Journal of Innovative Optical Health Sciences

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Adverse events associated with nonablative cutaneous visible and infrared laser treatment

Cited by 56 publications

References 19 publications

Optimal tattoo removal in a single laser session based on the method of repeated exposures

Optimal tattoo removal in a single laser session based on the method of repeated exposures

Infrared skin damage thresholds from 1319-nm continuous-wave laser exposures

Quantitative evaluation of enhanced laser tattoo removal by skin optical clearing

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