Adverse events of non-ablative fractional laser photothermolysis: a retrospective study of 856 treatments in 362 patients

Lee, Sang Min; Kim, Myoung Shin; Kim, Youn Jin; Won, Chong Hyun; Lee, Mi Woo; Choi, Jee Ho; Moon, Kee Chan; Chang, Sung Eun

doi:10.3109/09546634.2013.777151

Cited by 19 publications

(11 citation statements)

References 31 publications

(43 reference statements)

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“…Procedure pain was reported as mild to moderate in most subjects and adverse events were generally limited to immediate post‐treatment trace‐to‐moderate erythema and edema. No long‐term or serious adverse events reported, as seen in previous studies . Downtime following individual treatments lasted less than 2 days in most cases.…”

Section: Discussionsupporting

confidence: 68%

Treatment of facial photodamage and rhytides using a novel 1,565 nm non‐ablative fractional erbium‐doped fiber laser

et al. 2015

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Section: Discussionsupporting

confidence: 68%

Treatment of facial photodamage and rhytides using a novel 1,565 nm non‐ablative fractional erbium‐doped fiber laser

et al. 2015

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“…The first clinical study using an early 1,550‐nm erbium fiber prototype demonstrated mild‐to‐moderate improvement in periorbital wrinkles and skin texture in Caucasian patients after four treatments . Efficacy in improving wrinkles, skin texture, pore size, and dyspigmentation in the Asian population has similarly been demonstrated . Given the increased risk of PIH, a greater number of treatments with lower density is the preferred approach in treating skin of color.…”

Section: Non‐ablative Fractional Therapymentioning

confidence: 99%

“…In a retrospective review of 362 patients undergoing a total of 856 NAFL treatments with either 1,550‐nm erbium or 1,927‐nm thulium fiber laser, significant adverse events occurred in only 5%. This included prolonged erythema (>7 days) in 1.8%, PIH in 1.1%, and worsening of melasma in 0.9% .…”

Section: Non‐ablative Fractional Therapymentioning

confidence: 99%

Fractional resurfacing in the Asian patient: Current state of the art

Wat

Chan

2016

Lasers Surg Med

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Taking into account the unique characteristics and cosmetic concerns of the Asian population, fractional resurfacing can be considered a safe and effective option for the treatment of atrophic and hypertrophic scarring, and photorejuvenation in ethnic skin types. Select cases of melasma may be treated with fractionated non-ablative devices, but utilized with caution. The predominant complication associated with fractional resurfacing for these conditions is post-inflammatory hyperpigmentation (PIH) and rebound worsening of melasma. A greater number of treatments at lower density settings and wider treatment intervals typically produce the lowest risks of PIH without compromising treatment efficacy. Lasers Surg. Med. 49:45-59, 2017. © 2016 Wiley Periodicals, Inc.

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“…[1][2][3] Many studies have proven that this treatment modality can achieve desirable clinical results without serious adverse effects or longer downtime, which was the major limitation of ablative laser resurfacing. [4][5][6] Nonablative fractional laser therapy at 1,550 nm was approved by FDA for the treatment of periorbital rhytides, skin resurfacing, acne, and surgical scars. 5 It was also approved as an effective treatment modality for melasma and pigmented lesions.…”

Section: Introductionmentioning

confidence: 99%

“…When we consider the treatment of photoaging in Asian skin, dyspigmentation and postinflammatory hyperpigmentation always matters. 4 The modality to treat skin pigmentation, texture and wrinkles at the same time, is a must to ensure patient higher satisfaction. Therefore, dermal remodeling with 1,550 nm fractional laser treatment as well as improvement of superficial pigmentation and skin tones targeted by 1,927 nm thulium fiber fractional laser in a single session can be a promising treatment modality especially for photorejuvenation in Asian patients.…”

Section: Introductionmentioning

confidence: 99%

Clinical Benefit of Combination Treatment with 1,550 nm Fractional Laser and a New Wavelength at 1,927 nm on Photorejuvenation in Asian Patients

et al. 2014

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Background and Objectives Fractional laser using a new wavelength of 1,927 nm is expected to work on superficial skin conditions, while a 1,550 nm fractional laser was proven to be effective in dermal remodeling. We administered the combination treatment using 1,550 nm with 1,927 nm in a single session to determine its clinical efficacy and safety in photorejuvenation. Materials and Methods Patients who received combination treatment were analyzed. Two blinded assessors graded the degree of improvement using photographs based on a quartile scale (0-3). Erythema and melanin index were measured on the same spot before and after treatment. Patients' satisfaction and adverse effects were also reported. Results A total of 25 patients were evaluated. Patients were followed up for up to 12 months (4.04 ± 2.78 months). The overall clinical improvement was 2.12 (Pigment improvement: 1.92 ± 0.84, wrinkle and skin texture; 1.66 ± 0.54). Melanin index showed a substantial decrease after treatments. One patient experienced post inflammatory hyperpigmentation, which subsided with administration of a topical bleaching agent after six months. Conclusion Combination treatment with 1,550/1,927 nm may provide clinical benefit in Asian photoaged skin which contains a lot of pigmentation burden as well as wrinkles and other aging phenomenon.

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Adverse events of non-ablative fractional laser photothermolysis: a retrospective study of 856 treatments in 362 patients

Abstract: Non-ablative fractional laser skin treatment has a relatively low complication rate. The adverse events found were temporary and did not result in long-term or severe sequelae such as hypertrophic scarring, atrophic scarring or permanent pigmentary alteration.

Cited by 19 publications

References 31 publications

Treatment of facial photodamage and rhytides using a novel 1,565 nm non‐ablative fractional erbium‐doped fiber laser

Treatment of facial photodamage and rhytides using a novel 1,565 nm non‐ablative fractional erbium‐doped fiber laser

Fractional resurfacing in the Asian patient: Current state of the art

Clinical Benefit of Combination Treatment with 1,550 nm Fractional Laser and a New Wavelength at 1,927 nm on Photorejuvenation in Asian Patients

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