Adverse neonatal outcomes: examining the risks between preterm, late preterm, and term infants

Bastek, Jamie A.; Sammel, Mary D.; Paré, Emmanuelle; Srinivas, Sindhu K.; Posencheg, Michael A.; Elovitz, Michal A.

doi:10.1016/j.ajog.2008.08.002

Cited by 177 publications

(125 citation statements)

References 23 publications

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“…Pediatrics 2012;130:e265-e272 3 These neonatal morbidities include asphyxia, respiratory insufficiency, circulatory insufficiency, septicemia, hypoglycemia, hyperbilirubinemia, apnea, hypothermia, and feeding problems. [3][4][5][6] Some of these morbidities are severe enough to warrant admission to a tertiary NICU. Apart from the risk of neonatal morbidities, moderately preterm-born children are also more likely to have developmental delays at preschool age.…”

Section: Discussionmentioning

confidence: 99%

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Neonatal Morbidities and Developmental Delay in Moderately Preterm-Born Children

et al. 2012

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BACKGROUND AND OBJECTIVE: Children born moderately preterm (32–356/7 weeks’ gestation) are at increased risk of both neonatal morbidities and developmental delays in early childhood. It is unknown whether neonatal morbidities contribute to the increased risk of developmental delay. The objective of this study was to determine the effect of neonatal morbidities after moderately preterm birth on development at preschool age. METHODS: In a community-based, stratified cohort, parents of 832 moderately preterm children born in 2002 or 2003 completed the Ages and Stage Questionnaire when their child was 43 to 49 months old. Data on Apgar scores, asphyxia, tertiary NICU admission, hospital transfer, circulatory insufficiency, hypoglycemia, septicemia, mechanical ventilation, continuous positive airway pressure, apneas, caffeine treatment, and hyperbilirubinemia were obtained from medical records. We assessed associations of neonatal characteristics with developmental delay, adjusted for gender, small-for-gestational-age status, gestational age, and maternal education. RESULTS: Hypoglycemia and asphyxia were associated with developmental delay; odds ratios (ORs) were 2.42 (95% confidence interval [CI]: 1.23–4.77) and 3.18 (95% CI: 1.01–10.0), respectively. Tertiary NICU admission and hyperbilirubinemia had positive but statistically borderline nonsignificant associations with developmental delay: ORs were 1.74 (95% CI: 0.96–3.15) and 1.52 (95% CI: 0.94–2.46), respectively. No other neonatal morbidities were associated with developmental delay. In multivariate analyses, only hypoglycemia was associated with developmental delay (OR: 2.19; 95% CI: 1.08–4.46). CONCLUSIONS: In moderately preterm-born children, only hypoglycemia increased the risk of developmental delay at preschool age. A concerted effort to prevent hypoglycemia might enhance developmental outcome in this group.

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Section: Discussionmentioning

confidence: 99%

“…[25][26][27][28][29] They also have more difficulties in starting to feed orally and in achieving adequate feedings than termborn infants do. 3,5 Moreover, in contrast to early preterm-born infants, moderately preterm-born infants do not always routinely receive intravenous glucose infusions after birth.…”

Section: Tablementioning

confidence: 99%

Neonatal Morbidities and Developmental Delay in Moderately Preterm-Born Children

et al. 2012

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“…Various studies have shown that late-preterm infants have considerable short-and long-term morbidity and mortality; hence, every attempt must be made to prolong the pregnancy till 36 completed weeks [3,5,13]. Maternal and fetal indications for early delivery should be critically evaluated and risk benefit ratio should be judicially analyzed, keeping in mind the risks of neonatal morbidity.…”

Section: Discussionmentioning

confidence: 99%

Respiratory Morbidity in Late-Preterm Births: A Prospective Observational Study at a Tertiary Care Hospital

Shaikh

Faizi

Rai

2016

J Obstet Gynecol India

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Objectives To study the neonatal respiratory morbidity in late-preterm neonates.Materials and methods This study was done over a period of 6 months (November 2014-April 2015) including 120 late-preterm births at a tertiary referral center. Results Among the 120 late-preterm babies, 42 (35 %) developed respiratory morbidity. Respiratory distress syndrome (RDS) developed in 43 % of the babies who had not received steroid prophylaxis against 25.8 % receiving the same (p \ 0.05). Among the indicated late-preterm deliveries, 45 % of babies developed respiratory morbidity in comparison with 22 % of the babies born following spontaneous onset of labor (p \ 0.05). In the neonates with respiratory morbidity, male babies had a higher incidence than their female counterparts (48 vs. 24 % p \ 0.05). Severity of RDS declined from 57 % for babies born at 34 weeks of gestation to 26.3 % for those born at 36 weeks (p 0.14). With each advancing week of gestation a significant reduction in the need for ventilator support (78 % at 34 weeks to 15 % at 36 weeks of gestation p \ 0.05) was

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“…en cuanto a la morbilidad, se ha reportado que un tercio de los prematuros de 34 semanas de eG podrían hospitalizarse en el periodo neonatal, comparado con 0,5% de los rnt 19 . este riesgo, que se mantendría elevado durante el resto de la infancia, guarda relación inversa con la eG, y alcanza el nadir a las 39 semanas de gestación 12,20,21 . esta relación sugiere un efecto "dosisrespuesta" de la prematuridad y nos plantea que los niños nacidos de término temprano también sumarían mayor riesgo neonatal inmediato y de morbilidad posterior 18,22 .…”

Section: Morbi-mortalidad De Los Prematuros Tardíosunclassified

Prematuros tardíos: un grupo de riesgo de morbilidad a corto y largo plazo

2012

Rev. chil. pediatr.

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Adverse neonatal outcomes: examining the risks between preterm, late preterm, and term infants

Cited by 177 publications

References 23 publications

Neonatal Morbidities and Developmental Delay in Moderately Preterm-Born Children

Neonatal Morbidities and Developmental Delay in Moderately Preterm-Born Children

Respiratory Morbidity in Late-Preterm Births: A Prospective Observational Study at a Tertiary Care Hospital

Prematuros tardíos: un grupo de riesgo de morbilidad a corto y largo plazo

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