Adverse Outcome of Pregnancy Following Air Travel: A Myth or a Concern?

Chibber, Rachana; Al-Sibai, M. Hisham; Qahtani, Noura Al

doi:10.1097/01.ogx.0000224593.53082.4f

Cited by 4 publications

(9 citation statements)

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“…However, a study conducted by Chibber et al on 992 pregnant women [6], found that air travel was significantly associated with increased risk of preterm birth between 34 and 37 weeks (adjusted odds ratio 1.5, 95% CI: 1.2, 1.8). The dramatic differences between exposed and unexposed women in birth-weights (2684 ± 481 g vs. 3481 ± 703 g) as well as in gestational age at birth (36.1 ± 0.8 vs. 39.2 ± 2.1) and significant racial differences raise concerns regarding residual confounders which were not considered.…”

Section: Results Of the Study In The Context Of Other Observationsmentioning

confidence: 96%

“…Despite the plausible impact of environmental and physiological changes during a flight on pregnancy, and consequently on adverse pregnancy outcomes such as preterm delivery or low birth weight, data regarding this issue are scarce and controversial. A few studies found a significantly increased risk of preterm birth [6,7] and lower weight at birth [6] among women who have air traveled during pregnancy, while other studies have suggested no effect [8][9][10]. However, these studies, were limited in size, restricted to populations with predisposing factors, or lacked an adjustment for important confounding factors.…”

Section: Introductionmentioning

confidence: 99%

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Air travel during pregnancy and the risk of adverse pregnancy outcomes as gestational age and weight at birth: A retrospective study among 284,069 women in Israel between the years 2000 to 2016

Ram

Miller

et al. 2020

PLoS ONE

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Objective The American College of Gynecology (ACOG) recommendation does not limit air travel during pregnancy, yet the evidence for air travel effect on adverse pregnancy outcomes is limited and debatable. Study objectives were to examine the association between air travel during pregnancy and preterm birth together with decreased birth weight. Study design A retrospective cohort study. Methods The study evaluated 628,292 women who gave birth to singleton infants from 9/2000 to 9/ 2016 and classified them into "air travel during pregnancy" or not, based on flight insurance as proxy. Multiple linear regression models were utilized to examine the relationship between air travel during pregnancy and newborn's gestational age and birth weight, while accounting for socioeconomic status, diabetes, high-risk pregnancies, and smoking. Results A total of 41,677 (6.6%) births of women who air traveled during pregnancy was included, and 586,615 (93.4%) births of women who did not. Air travel during pregnancy was associated with a statistically significant (p<0.0001) but negligible increase in birth weight (9 gr. 95% CI: 4.8 to 14.5 gr.) and gestational age (0.36 days. 95%

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Section: Results Of the Study In The Context Of Other Observationsmentioning

confidence: 96%

Section: Introductionmentioning

confidence: 99%

Air travel during pregnancy and the risk of adverse pregnancy outcomes as gestational age and weight at birth: A retrospective study among 284,069 women in Israel between the years 2000 to 2016

Ram

Miller

et al. 2020

PLoS ONE

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show abstract

“…Chibber et al presented conflicting results with a larger sample size. They supported that primigravid women who travel by air appear to be at a higher risk for preterm birth [42]. Such researches are vital and multicentric large studies are required to confirm these findings and to define new strategies for preventing adverse birth outcomes with progesterone magnesium or ritodrine.…”

Section: Association Of Air Travel and Preterm Labormentioning

confidence: 91%

Air travel during pregnancy: an update review and practical recommendation

Csorba¹,

Tsikouras²,

Bothou³

et al. 2019

Clin. Exp. Obstet. Gynecol.

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Objective: Nowadays it is easier for pregnant women to travel abroad. The purpose of this review is to insure that healthcare providers advise pregnant women of the risks to travel by airplane. Materials and Methods: The authors provide an overview of the risks of thrombosis in pregnancy to travel by airplane and the risks of miscarriage and preterm labor. This study is based on electronic literature using the best available evidence from PubMed, Medline, Google Scholar, the American College of Obstetricians and Gynecologists (ACOG), the American College of Chest Physicians (ACCP), the Royal College of Obstetricians and Gynecologists (RCOG), and the British Thoracic Society (BTS). Results: In the lack of evidence-based information, physicians and pregnant women should only rely on guidelines and experts' opinions. Conclusions: In the absence of a reasonable expectation for obstetric or medical complications, occasional air travel is safe in pregnancy. The specific airline recommendations should be always kept in mind.

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“…This drop-in air pressure is largely compensated for by the cabin pressure in the aircraft (equivalence to an altitude of 1524-2438 m above sea level) so that an altitude of about 12,200 m is tolerated by the passengers without hypoxic stress. The partial pressure of oxygen in the arterial blood depends on the lung function (cave: chronic obstructive pulmonary diseases); in healthy passengers it drops from 95 mmHg to 53-78 mmHg in the airplane, and the arterial oxygen saturation decreases from 97 to 99% to 90-94% [36][37][38][39][40][41].…”

Section: General Effects Of Travel In Pregnant Women's Healthmentioning

confidence: 99%

Vein Thrombosis Risk in Women and Travel

Tsikouras¹,

Anthoulaki²,

Deftereou³

et al. 2021

Tourism

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Deep vein thrombosis (DVT) of the lower limbs is a serious condition that can lead to pulmonary embolism (PE) in about 15-24% of cases. If it is not diagnosed/ treated timely, nearly 15% of these PE are lethal. The relationship between travel and staying in the same position for a long time is well-known since World War II. Generally, it is more frequent in air flights. It is also associated with the economic downturn in airplanes because passengers have limited space and have greater difficulty of moving. It is estimated that approximately 1-6% of long-haul passengers arrive at their destination with a clot in their veins, but most DVT are asymptomatic.

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Adverse Outcome of Pregnancy Following Air Travel: A Myth or a Concern?

Cited by 4 publications

References 0 publications

Air travel during pregnancy and the risk of adverse pregnancy outcomes as gestational age and weight at birth: A retrospective study among 284,069 women in Israel between the years 2000 to 2016

Air travel during pregnancy and the risk of adverse pregnancy outcomes as gestational age and weight at birth: A retrospective study among 284,069 women in Israel between the years 2000 to 2016

Air travel during pregnancy: an update review and practical recommendation

Vein Thrombosis Risk in Women and Travel

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