Adverse outcomes of sick leave due to mental disorders: A prospective study of discordant twin pairs

Mather, Lisa; Blom, Victoria; Bergström, Günnar; Svedberg, Pia

doi:10.1177/1403494817735755

Cited by 19 publications

(15 citation statements)

References 119 publications

(222 reference statements)

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“…Hence, there is a possibility that familial factors influence the associations between CWP and CMDs with future SA and DP. To our knowledge, few studies have had access to twin data to examine adverse outomes of CWP and CMDs among individuals with a history of SA [18]. By studying twins that share 50-100% of their genetic material and rearing environment a possibility is provided to adjust for those unmeasured factors.…”

Section: Introductionmentioning

confidence: 99%

Adverse outcomes of chronic widespread pain and common mental disorders in individuals with sickness absence – a prospective study of Swedish twins

et al. 2020

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Background: Chronic widespread pain (CWP) and common mental disorders (CMDs) are common public health problems, but little is known about the role of CWP and CMDs on future adverse outcomes among work disabled individuals. The aims of the study were to investigate the associations between CWP and CMDs with subsequent disability pension (DP), long-term unemployment (> 90 days) and all-cause mortality in individuals with sickness absence (SA) and whether the associations were explained by familial factors. Methods: In this prospective cohort study, 7884 Swedish twins born between 1933 and 1985 were included and baseline data were gathered from a questionnaire in 1998 to 2006. Register data were used for obtaining information regarding demographics, SA, DP, unemployment and mortality. Cox proportional hazards regressions were used to calculate Hazard Ratios (HR) with 95% Confidence Intervals (CI) for the associations between CWP and/or CMDs with DP, unemployment and mortality, while conditional Cox models for twin pairs provided control for familial confounding. Results: Having either CWP or CMDs among those with a history of SA was associated with a higher risk of DP and all-cause mortality than individuals without CWP and CMDs after controlling for socio-demographic and health factors. Moreover, sick-listed individuals with both CWP and CMDs had a higher risk of DP while those who only had CMDs had a higher risk of long-term unemployment compared to those without CWP and CMDs. The association between CMDs with DP and long-term unemployment was no longer significant when controlling for familial factors. Conclusions: CMDs was a risk factor for DP, unemployment and mortality among individuals with SA, while CWP seems to be important in relation to future DP and mortality. Familial factors played a role in the associations between CMDs and DP and CMDs and unemployment.

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Section: Introductionmentioning

confidence: 99%

Adverse outcomes of chronic widespread pain and common mental disorders in individuals with sickness absence – a prospective study of Swedish twins

et al. 2020

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“…There are several indicators which would support such a stance; for example, evidence-based recommendations for common back pain emphasize the importance of maintaining normal activities, including gainful work, to lower the risk of disability [17]. For Common Mental Disorders (CMDs) the importance of returning to work despite remaining psychological symptoms is also considered as crucial to avoid negative long-term effects such as prolonged sick leave, unemployment, social isolation and financial problems [18][19][20]. However, the availability of resources and support at work can be expected to be of vital importance when an employee who does not feel well goes to work [18,19] To the best of the authors' knowledge there exists no published comprehensive longitudinal study of the potential moderating impact of psychosocial job resources on the relation between presenteeism and health.…”

Section: Introductionmentioning

confidence: 99%

A Resourceful Work Environment Moderates the Relationship between Presenteeism and Health. A Study Using Repeated Measures in the Swedish Working Population

Bergström

Gustafsson

Aboagye

et al. 2020

IJERPH

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The objective of this study was to investigate if the psychosocial work environment moderates the proposed negative impact of presenteeism on future general health. We expect that the negative impact of presenteeism on general health is weaker if the psychosocial work environment is resourceful, and more pronounced if the environment is stressful. Data were derived from the 2008–2018 biennial waves of the Swedish Longitudinal Occupational Survey of Health (SLOSH). The final analytic sample consisted of n = 15,779 individuals. We applied repeated measures regression analyses through generalized estimating equations (GEE). Results from the autoregressive GEE models showed statistically significant interaction terms between presenteeism and all four investigated moderators, i.e., job demands, job control, job support and job strain. The results indicate that the psychosocial work environment moderates the negative association between presenteeism and general health and illustrates a buffering effect of the psychosocial work environment. A possible explanation for these results may be that psychosocially resourceful work environments give room for adjustments in the work situation and facilitate recovery. The results also indicate that by investing the psychosocial work environment employers may be able to promote worker health as well as prevent reduced job performance due to presenteeism.

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“…Hence, some indications exist that severity of the depression or an adverse effect of the sick leave itself may also play a role in the association between sick leave and mortality. In a previous twin study, we found that the increased risk of subsequent sick leave, unemployment and disability pension was independent of familial factors [9]. Another twin study that investigated the influence of familial factors on the association between sick leave, all causes, and mortality found only minimal influence [24].…”

Section: Introductionmentioning

confidence: 76%

“…Sick leave due to mental disorders has been found to have a negative effect on future work life, such as a higher risk of unemployment and a lower income [7][8][9]. Sick leave has also been associated with a number of adverse health outcomes, such as poor self-rated health [10,11] and early death [12].…”

Section: Introductionmentioning

confidence: 99%

Sick leave due to mental disorders, morbidity and mortality: a prospective study of discordant twin pairs

Mather

Narusyte

Ropponen

et al. 2019

Soc Psychiatry Psychiatr Epidemiol

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Purpose To investigate if sick leave due to mental disorders increases the risk of morbidity measured by inpatient and specialized outpatient care, and mortality among women and men, independent of familial factors. Methods An open cohort study of 4979 twin pairs discordant for sick leave due to mental disorders was conducted in 2005-2013. Twins were followed up in the cause of death and national patient registries until the end of study, emigration, death, and inpatient and specialized outpatient care. Conditional Cox proportional hazard regression, adjusting for the familial factors shared by the twins, was used to calculate hazard ratios (HR) with 95% confidence intervals (CI). In case of non-proportional hazards, time-varying covariates were used. Results Sick leave due to mental disorders increased the risk for inpatient care among men (

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Adverse outcomes of sick leave due to mental disorders: A prospective study of discordant twin pairs

Abstract: Sick leave due to mental disorders increased the risk of reoccurring sick-leave within two years, disability pension and unemployment, independent of genetics and shared environment.

Cited by 19 publications

References 119 publications

Adverse outcomes of chronic widespread pain and common mental disorders in individuals with sickness absence – a prospective study of Swedish twins

Adverse outcomes of chronic widespread pain and common mental disorders in individuals with sickness absence – a prospective study of Swedish twins

A Resourceful Work Environment Moderates the Relationship between Presenteeism and Health. A Study Using Repeated Measures in the Swedish Working Population

Sick leave due to mental disorders, morbidity and mortality: a prospective study of discordant twin pairs

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