“…In addition to this severe psychological withdrawal, symptoms are described including anxiety, restlessness, irritability, depression, self-mutilation, suicide fantasy and suicide attempts (10,15,32), aggressive outbursts and psychotic episodes (18). It has been noted that regular cannabis users resent deprivation (20,39) and are intent on returning to its use (13,25), despite unpleasant reactions. It has been pointed out that while some may be able to use cannabis products purely for the purposes of pleasure, other individuals show the major characteristic of psychological dependence in that they are unable to feel well or to function adequately without regular use of the drug (13,14,32,43).…”