“…The published data about cutaneous adverse events from three major completed SARS-CoV-2 vaccine trials phases I, II, and III in the US, UK, Brazil, and South Africa demonstrated the development of rosacea flare, pruritus; cellulitis after ChAdOx1 nCoV-19, maculopapular rash, and transient urticaria on both legs five days after receiving the first dose of Moderna vaccine (Baden et al, 2021), as well as, 0.63% of hypersensitivity related to Pfizer-BioNTech vaccine (Munavalli et al, 2021). With filler injections (Sayan at al., 2021), a recent controversy overuse of COVID-19 vaccinations has been dea recent controversy over the use of COVID-19 vaccinations has been seen. FAD brief to Moderna vaccine reported reactions to dermal filler in different areas in three patients after vaccination, two of them had a facial swelling after six months of filler injection, and the other one had a lip swelling with unknown time of filler injection; however, there is no hereditary angioedema or positive SARS-CoV-2 (Rice et al, 2021).…”