Adverse reactions to bovine collagen implants. Additional evidence for immune response gene control of collagen reactivity in humans

Trentham, David E.

doi:10.1001/archderm.122.6.643

Cited by 5 publications

(3 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Mechanistically, when collagen membranes are placed, they mainly act as a physical barrier in the prevention of cell ingrowth from surrounding tissue, to create and allow a suitable microenvironment for complete regeneration in the area of lesion [ 49 , 50 , 51 ]. In its biological participation, it also facilitates the recruitment of CD68-positive monocyte/macrophage cells and periostin-positive osteoprogenitors from surrounding tissues to adhere to the membranes.…”

Section: Current Applications Mechanism Of Action and Limitations Of ...mentioning

confidence: 99%

“…It has been reported that these materials have a potential in being a suitable environment for bone mineralization, neovascularization, and growth factor adhesion [ 65 ]. However, they are less considered for graft substitution as they exhibit high risk of adverse immune responses and possess poor structural integrity, especially in the long-term application of grafting case studies [ 50 , 66 ].…”

Section: Current Applications Mechanism Of Action and Limitations Of ...mentioning

confidence: 99%

See 1 more Smart Citation

Collagen-Based Biomaterials in Periodontal Regeneration: Current Applications and Future Perspectives of Plant-Based Collagen

et al. 2022

View full text Add to dashboard Cite

Collagen is the most widely distributed protein in human body. Within the field of tissue engineering and regenerative medical applications, collagen-based biomaterials have been extensively growing over the past decades. The focus of this review is mainly on periodontal regeneration. Currently, multiple innovations of collagen-based biomaterials have evolved, from hemostatic collagen sponges to bone/tissue regenerative scaffolds and injectable collagen matrices for gene or cell regenerative therapy. Collagen sources also differ from animal to marine and plant-extracted recombinant human type I collagen (rhCOL1). Animal-derived collagen has a number of substantiated concerns such as pathogenic contamination and transmission and immunogenicity, and rhCOL1 is a potential solution to those aforementioned issues. This review presents a brief overview of periodontal regeneration. Also, current applications of collagen-based biomaterials and their mechanisms for periodontal regeneration are provided. Finally, special attention is paid to mechanical, chemical, and biological properties of rhCOL1 in pre-clinical and clinical studies, and its future perspectives in periodontal regeneration are discussed.

show abstract

Section: Current Applications Mechanism Of Action and Limitations Of ...mentioning

confidence: 99%

Section: Current Applications Mechanism Of Action and Limitations Of ...mentioning

confidence: 99%

Collagen-Based Biomaterials in Periodontal Regeneration: Current Applications and Future Perspectives of Plant-Based Collagen

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Importantly DAMPs do not only include foreign components and features but also intrinsic molecules present in unusual form or in unusual location. Textbook examples of DAMPs include strictly intracellular proteins (such as chromosomal protein HMGB-1 or histones) which enter systemic circulation only upon death or host cells [32] or circulating fragments of extracellular matrix [33]. Presence of DAMPs is thus indicative of tissue damage and acts as a trigger of the systemic protective response.…”

Section: Why and How Is Genotoxic Damage Visible To The Immune System?mentioning

confidence: 99%

DNA damage in protective and adverse inflammatory responses: Friend of foe?

Poliezhaieva

Ermolaeva

2017

Mechanisms of Ageing and Development

View full text Add to dashboard Cite

BioplastiqueTM : A new biphasic polymer for minimally invasive injection implantation

Ersek

Beisang

1992

Aesth. Plast. Surg.

View full text Add to dashboard Cite

The search for prosthetic materials that are biocompatible, nontoxic, and permanent led the authors to develop a micronized, inert, biphasic polymer particle for permanent soft tissue augmentation which neither migrates nor is absorbed by the body. Placed in a bioexcretable gel carrier, these textured microparticles are easily implanted using a specially designed blunt-tipped cannula with local anesthesia on an outpatient basis. Research using this implant material, Bioplastique (Bioplasty, St. Paul, MN), in rabbits has shown that when the textured particle size is maintained within a critical range, neither particle migration nor storage disease occurs. The gel carrier is rapidly phagocytized and replaced by fibrin matrix within a few days. Host collagen then gradually forms a fibrotic capsule around each textured particle, making use of the naturally occurring foreign body reaction to create a stable inplant. After being followed for over two years, Bioplastique has proven to be useful in many clinical applications with few complications.

show abstract

Adverse reactions to bovine collagen implants. Additional evidence for immune response gene control of collagen reactivity in humans

Cited by 5 publications

References 10 publications

Collagen-Based Biomaterials in Periodontal Regeneration: Current Applications and Future Perspectives of Plant-Based Collagen

Collagen-Based Biomaterials in Periodontal Regeneration: Current Applications and Future Perspectives of Plant-Based Collagen

DNA damage in protective and adverse inflammatory responses: Friend of foe?

BioplastiqueTM : A new biphasic polymer for minimally invasive injection implantation

Contact Info

Product

Resources

About