Advice to walk after meals is more effective for lowering postprandial glycaemia in type 2 diabetes mellitus than advice that does not specify timing: a randomised crossover study

Reynolds, Andrew; Mann, Jim; Williams, Sheila; Venn, Bernard

doi:10.1007/s00125-016-4085-2

Cited by 84 publications

(96 citation statements)

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“…The study by Van Dijk et al [11] demonstrated that walking after meal for 15 min although could reduce PPG in type 2 diabetic patients, but the reduction did not reach statistical significance. In other studies, at least 20 minutes of walking after one meal or 10-15 minutes per each meal everyday demonstrated significant glycemic reduction [8,9,12,19]. Pahra et.al [8] demonstrated that post-meal walking for 1,500-1,600 steps for 15 min after three main meals could significantly decrease the HbA1c levels of 0.9% at 8 th weeks.…”

Section: Discussionmentioning

confidence: 94%

“…Several studies performed walking after breakfast [5][6][7], of which maximum glucose excursion occurred [20]. A study by Reynold et al [9] showed that walking after meal with the most substantial amount of carbohydrate, could decrease PPG more effectively than walking after other meals. Since most participants walked after dinner and dinner was not a main meal in our study (S2 Table), the magnitude of PPG reduction with post-meal walking may be substantially under-estimated.…”

Section: Discussionmentioning

confidence: 99%

“…Increased physical activity is recommended as the mainstay therapy for type 2 diabetic patients especially those who are overweight or obese [3,4]. Recent studies demonstrate that increased physical activity by walking after meal (post-meal walking) for 10-20 minutes can reduce postprandial plasma glucose (PPG) better than walking before meal [5][6][7][8][9][10][11][12]. Colberg et al [12] showed that post-dinner walking in type 2 diabetic subjects decreased PPG at 1 hour after meal about 40 mg/dl compared with those without.…”

mentioning

confidence: 99%

“…Colberg et al [12] showed that post-dinner walking in type 2 diabetic subjects decreased PPG at 1 hour after meal about 40 mg/dl compared with those without. Pahra et al [8] and Reynolds et al [9] respectively demonstrated that HbA1c and glycated albumin were reduced with 10-15 minutes walking after three main meals for two and eight weeks. The effect on PPG reduction has been observed since first time of walking and is not insulin dependent [10].…”

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confidence: 99%

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Glycemic effect of post-meal walking compared to one prandial insulin injection in type 2 diabetic patients treated with basal insulin: A randomized controlled cross-over study

et al. 2020

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Studies demonstrate that post-meal walking decreases postprandial hyperglycemia in type 2 diabetic patients but it has never been tested with the active treatment comparator. The objective of this study was to determine the effect of post-meal walking on glycemic control compared with one prandial insulin in type 2 diabetic patients who failed basal insulin. A randomized controlled cross-over study of post-meal walking or one prandial insulin was done in type 2 diabetic patients who were being treated with basal insulin between May 2017 and March 2018. In post-meal walking group, patients walked after meal for 15-20 minutes one meal a day every day for 6 weeks. In prandial insulin (basal plus) group, one prandial insulin was injected before breakfast or main meal with rapid-acting insulin. The primary outcome was a difference in HbA1c reduction in post-meal walking compared with basal plus groups. Fourteen patients completed the study. By intention-to-treat analysis, HbA1c was reduced by -0.05(range:-1.08 to 0.74) and -0.19(range:-0.8 to 0.56) % in post-meal walking and basal plus groups respectively. By per-protocol analysis, post-meal walking and basal plus groups decreased HbA1c by 0.13(range:-0.74 to 1.08) and 0.2(range:-0.56 to 0.8) %, respectively. There was were no significant differences in HbA1c reduction from baseline in each group and between groups in both intention-to-treat and per-protocol analysis. Fructosamine levels were decreased by 17.5(-59 to 43) and 10(-15 to 40) μmol/L, respectively at 3 and 6 weeks in post-meal walking group whereas the respective changes in basal plus group were 12.5(-17 to 64) and 17.5(-28 to 38) μmol/L and there were no significant differences in fructosamine reduction from baseline in each group and between groups. In conclusion, although post-meal walking might be as effective as one prandial insulin to improve glycemic control in type 2 diabetic patients who failed basal insulin but the magnitude of PLOS ONE

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Section: Discussionmentioning

confidence: 94%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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confidence: 99%

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Glycemic effect of post-meal walking compared to one prandial insulin injection in type 2 diabetic patients treated with basal insulin: A randomized controlled cross-over study

et al. 2020

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“…13 IAUC was calculated in Microsoft Excel using the trapezium rule 14 and a difference of 20% was deemed to be clinically meaningful in line with a previous study. 15 Sensitivity analyses were conducted to investigate whether subtracting the area below baseline (i.e. positive iAUC) or including the area below baseline (i.e.…”

Section: Discussionmentioning

confidence: 99%

The Acute Effects of Breaking Up Seated Office Work With Standing or Light-Intensity Walking on Interstitial Glucose Concentration: A Randomized Crossover Trial

Brocklebank¹,

Falconer²,

Leary³

et al. 2017

Journal of Physical Activity and Health

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General rightsThis document is made available in accordance with publisher policies. Please cite only the published version using the reference above. Full terms of use are available: http://www.bristol.ac.uk/pure/about/ebr-terms Results: Five-hour interstitial glucose incremental area under the curve (iAUC) was 55.5% lower after sitting interrupted by light-intensity walking compared with after uninterrupted sitting (95% CI, -104.2% to -6.8%). There was also a suggestion of a beneficial effect of regular standing breaks, particularly in overweight men, although they were not as effective as the walking breaks (mean difference [95% CI], -29.6% [-73.9% to 14.7%]).Conclusions: Regularly breaking up prolonged sitting lowers postprandial glycemia in middle-aged adults without metabolic impairment.Prolonged sitting and glucose regulation

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Type and timing of exercise during lunch breaks for suppressing postprandial increases in blood glucose levels in workers

Yoko

Jiang

2021

Journal of Occupational Health

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Objectives Suppression of postprandial hyperglycemia may aid in preventing lifestyle‐related diseases in working people. The present study aimed to identify the types and timings of exercises that can be performed by working people during a 60‐minute lunch break that are effective in attenuating postprandial increases in blood glucose levels. Methods Healthy working people aged 20 years and older were subjected to aerobic (AER) or resistance (RES) exercise before (Pre) and after (Post) lunch, assuming a 60‐minute lunch break, with fixed 20‐minute lunch and rest periods. These exercise sessions of 4 different patterns were performed by each participant. Serial measurements of blood glucose levels were obtained every 15 minute using a Flash Glucose Monitoring System. Results Data were analyzed for 11 participants who completed the protocol. Our incremental area under the curve (IAUC) analysis indicated that the AER‐Post condition was associated with the most significant hypoglycemic effect, followed by the AER‐Pre condition. Although the RES‐Post showed no significant difference, a decrease in the IAUC comparison is apparent. However, the RES‐Pre condition exerted no acute effect on blood glucose levels. Conclusions Workers may benefit from a 20‐minute aerobic exercise period, following a 20‐minute lunch and a 20‐minute rest period, as this may help prevent progression to diabetes. Furthermore, performing 20‐minute aerobic exercises prior to lunch may also attenuate postprandial increases in blood glucose levels. Therefore, if the lunch breaks are short, aerobic exercises are recommended before lunch.

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Advice to walk after meals is more effective for lowering postprandial glycaemia in type 2 diabetes mellitus than advice that does not specify timing: a randomised crossover study

Abstract: ACTRN12613000832774 FUNDING: : This study was supported by grants from the University of Otago and the New Zealand Artificial Limb Service. Glycated albumin reagents were provided by Asahi Kasei.

Cited by 84 publications

References 35 publications

Glycemic effect of post-meal walking compared to one prandial insulin injection in type 2 diabetic patients treated with basal insulin: A randomized controlled cross-over study

Glycemic effect of post-meal walking compared to one prandial insulin injection in type 2 diabetic patients treated with basal insulin: A randomized controlled cross-over study

The Acute Effects of Breaking Up Seated Office Work With Standing or Light-Intensity Walking on Interstitial Glucose Concentration: A Randomized Crossover Trial

Type and timing of exercise during lunch breaks for suppressing postprandial increases in blood glucose levels in workers

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