Considering the vibration generated by a propeller-driven UAV or encountering gust, the propeller will perform a very complex follower motion. A pitch and rotating coupled motion is proposed in the present work that can take more complex unsteady performance of follower force than a regular fixed-point rotating motion. In order to evaluate the unsteady follower force and conduct parametric study, an extensive ground test bench was designed for this purpose where the whole test system was driven by a linear servo actuator and the follower force was measured by a 6-component balance. For CFD simulation, coupled motion in particular needs detailed unsteady aerodynamic model; therefore, a high-fidelity CFD-based study integrated with the overset mesh method was complemented to solve the unsteady fluid of varying conditions. The results suggest that a significant influence on unsteady follower force is observed, and the mean value of in-plane force does not equal to zero during the coupled motion process. Compared with the regular fixed-point rotation of propeller, the fluctuation frequency of follower force in present work couples the rotation and pitch motion frequencies. In addition, the oscillation amplitude of out-plane force and torque is positively related with the pitch frequency, pitch amplitude, and relative length from leading edge of wing to the rotation center. For example, the oscillation amplitude of 1-blade’s out-plane force and torque increases by 57.122% and 66.542% for the 5 Hz-5 deg case compared with the 5 Hz-3 deg case, respectively. However, the torque is not sensitive to frequency of pitch motion. The generally excellent agreement evident between the ground test and numerical simulation results is important as guidance for our future investigation on “dynamic” aerodynamic performance of a propeller-driven UAV.