Aerobic exercise in adults with chronic kidney disease (CKD): a meta-analysis

Pei, Gaiqin; Tang, Yi; Li, Tan; Tan, Jindong; Ge, Long; Qin, Wei

doi:10.1007/s11255-019-02234-x

Cited by 69 publications

(65 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Usually, when exercise therapy trials have documented general well-being or quality-of-life outcomes, some degree of trend towards improvement is seen. Convincing findings of improvement in HRQoL from meta-analyses are available for knee and hip osteoarthritis, rheumatoid arthritis, fibromyalgia, Parkinson’s disease, schizophrenia, and chronic kidney disease, along with cancer survivors (Table 5) [25, 27, 28, 35, 36, 43, 46, 77-84]. When reporting on quality of life, possible sub-domains that are improved in the absence of improvement in total scores are not formally reported in this review.…”

Section: Methodsmentioning

confidence: 99%

Summary of the Effects of Exercise Therapy in Non-Communicable Diseases: Clinically Relevant Evidence from Meta-Analyses of Randomized Controlled Trials

Kujala

2021

Preprint

View full text Add to dashboard Cite

There is strong evidence that exercise therapy leads to better measured and self-reported physical fitness and function in patients with chronic diseases, along with improvements in body composition. The evidence for other health benefits has not been summarized as systematically across different chronic diseases. Given the volume of research that has appeared in the past decade, this review of meta-analyses of randomized controlled trials (RCTs) in patients with specific chronic diseases summarizes the evidence regarding exercise therapy for various outcomes to help practitioners in prescribing exercise therapy for their patients. Meta-analyses published before Jan 1, 2021, based on at least four RCTs, and investigating the effect of exercise therapy on the same outcome among patients with a specific chronic disease were screened. These meta-analyses show that, in addition to improvements in fitness and function, various cardio-metabolic risk factor levels are improved in most of the common cardio-metabolic diseases, pain is reduced in musculoskeletal diseases, mood (depression and anxiety) and health-related quality of life are improved in various disease categories, and disease-specific indicators of disease progression are improved for conditions such as type 2 diabetes, hypertension, coronary heart disease, heart failure, claudication, chronic obstructive pulmonary disease, rheumatoid arthritis, fibromyalgia, depression, anxiety, and schizophrenia. Physicians should consider prescribing exercise to their patients with chronic disease conditions to improve their physical fitness, mood, and health-related quality of life and to slow down the progression of disease. This improves a patient's possibility to enjoy an active and independent life.

show abstract

Section: Methodsmentioning

confidence: 99%

Summary of the Effects of Exercise Therapy in Non-Communicable Diseases: Clinically Relevant Evidence from Meta-Analyses of Randomized Controlled Trials

Kujala

2021

Preprint

View full text Add to dashboard Cite

show abstract

“…Generally speaking, aerobic exercise greatly improves cardiopulmonary function and cardiovascular indicators, while resistance exercise mainly affects muscle strength and body composition. Pei et al’s 8 study showed that aerobic exercise can improve cardiopulmonary function of chronic kidney disease patients while improving quality of life. Song et al’s 9 research showed that progressive resistance exercise improved body composition and dialysis patients’ quality of life.…”

Section: Introductionmentioning

confidence: 99%

Effects of combined aerobic and resistance exercise on renal function in adult patients with chronic kidney disease: a systematic review and meta-analysis

Yang

Wang

et al. 2020

Clin Rehabil

View full text Add to dashboard Cite

Objectives: Combined aerobic and resistance exercise (CARE) is beneficial for improving renal function. To confirm this, we conducted a meta-analysis to evaluate the effects of CARE on renal function in adult patients with chronic kidney disease (CKD). Date sources: The last date of search was 22 February 2020. We searched Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase, Allied and Complementary Medicine (AMED), CINAHL, Web of Science, SPORTDiscus, and three Chinese databases (China National Knowledge Infrastructure (CNKI), Wangfang, Journal Integration Platform (VIP)) for articles of randomized and quasi-randomized controlled trials. Methods: We used the Cochrane tool and the JBI Critical Appraisal checklist to assess randomized controlled trials and quasi-randomized controlled trials, respectively. Result: A total of 12 studies and 745 patients were included. Compared with usual care or no exercise, CARE resulted in a significant improvement in the estimated glomerular filtration rate (between-group analysis: mean difference (MD) =5.01, 95% confidence interval (CI): 2.37 to 7.65; within-group analysis: MD = 3.01, 95% CI: 0.86 to 5.16). The serum creatinine levels also showed a significant improvement after CARE (between-group analysis: MD = −8.57, 95% CI: −13.71 to −3.43; within-group analysis: MD = −6.33, 95% CI: −10.23 to −2.44). Patients who performed CARE also demonstrated a decline in the blood pressure in the within-group analysis (systolic blood pressure: MD = −5.24, 95% CI: −7.93 to −2.54; diastolic blood pressure: MD = −3.63, 95% CI: −5.35 to −1.91). However, there were no significant differences in proteinuria, lipid levels, physical composition, and quality of life. Conclusion: The study results support the concept that CARE intervention improves renal function. It provides strong evidence for guiding clinical decisions and implementing renal rehabilitation exercises.

show abstract

“…All types of exercise resulted in improvements in performance status, but resistance exercise seems to be the superior. However, we cannot ignore the fact that aerobic exercise is associated with improved cardiorespiratory function, lipid profile improvement, and an overall improvement in mental health and QoL [ 42 ]. Therefore, combined exercise could be the ideal choice for HD patients, providing a combination of positive results in many aspects of the patients’ lives.…”

Section: Discussionmentioning

confidence: 99%

“…In previous systematic reviews, the beneficial effects of exercise on the physical health of patients undergoing HD [ 33 , 34 , 35 , 36 , 37 , 38 ] as well as on the QoL were illuminated [ 39 , 40 , 41 , 42 , 43 , 44 , 45 ]. In two studies by Lu et al [ 46 ] and Molsted et al [ 47 ], the positive effects of exercise on muscle mass and muscle strength in patients undergoing HD were also stressed out.…”

Section: Introductionmentioning

confidence: 99%

The Effect of Exercise on Nutritional Status and Body Composition in Hemodialysis: A Systematic Review

et al. 2020

View full text Add to dashboard Cite

Chronic kidney disease (CKD) is associated with aggravating factors which can affect both body composition and nutritional status. The purpose of the present systematic review was to investigate the potential effects of any physical activity on body composition or nutritional status among patients with stage 5 CKD undergoing hemodialysis (HD). A literature search on PubMed, Scopus, Web of Science, Google Scholar, and Cochrane was conducted and 14 randomized clinical trials were included. Skeletal muscle index and mid-arm muscular circumference increased after resistance exercise, and the results on body mass index, % body fat, and lean body mass varied. Serum albumin and C-reactive protein, in most cases, showed a slight increase and decrease, respectively. An improvement was also observed in body strength and overall performance status. The results suggest that physical activity can be beneficial for both the body composition and nutritional status of patients undergoing HD and can help in the prevention of sarcopenia. However, further research is needed mainly in the field of nutritional status.

show abstract

Aerobic exercise in adults with chronic kidney disease (CKD): a meta-analysis

Cited by 69 publications

References 43 publications

Summary of the Effects of Exercise Therapy in Non-Communicable Diseases: Clinically Relevant Evidence from Meta-Analyses of Randomized Controlled Trials

Summary of the Effects of Exercise Therapy in Non-Communicable Diseases: Clinically Relevant Evidence from Meta-Analyses of Randomized Controlled Trials

Effects of combined aerobic and resistance exercise on renal function in adult patients with chronic kidney disease: a systematic review and meta-analysis

The Effect of Exercise on Nutritional Status and Body Composition in Hemodialysis: A Systematic Review

Contact Info

Product

Resources

About