Aerobic exercise intervention improves aerobic capacity and movement initiation in Parkinson's disease patients

Bergen, J. L.; Toole, Tonya; Elliott, Robert G.; Wallace, Brian; Robinson, Keith; Maitland, Charles G.

doi:10.3233/nre-2002-17209

Cited by 115 publications

(48 citation statements)

References 30 publications

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“…The clinical importance of movement economy in PD is indirectly supported by several studies demonstrating aerobic exercise benefit for people with PD. 5,[41][42][43][44][45] Building from this study, future work should evaluate mechanisms related to poorer walking economy and the response of walking economy to various interventions.…”

Section: Discussionmentioning

confidence: 99%

Walking economy in people with Parkinson's disease

et al. 2009

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Gait dysfunction is an early problem identified by patients with Parkinson's disease (PD). Alterations in gait may result in an increase in the energy cost of walking (i.e., walking economy). The purpose of this study was to determine whether walking economy is atypical in patients with PD when compared with healthy controls. A secondary purpose was to evaluate the associations of age, sex, and level of disease severity with walking economy in patients with PD. The rate of oxygen consumption (VO 2 ) and other responses to treadmill walking were compared in 90 patients (64.4±10.3 yr) and 44 controls (64.6±7.3 yr) at several walking speeds. Pearson correlation coefficients (r) were calculated to determine relationships of age, sex, and disease state with walking economy in PD patients. Walking economy was significantly worse in PD patients than in controls at all speeds above 1.0 mph. Across all speeds, VO 2 was 6 to 10% higher in PD patients. Heart rate, minute ventilation, respiratory exchange ratio, and rating of perceived exertion were correspondingly elevated. No significant relationship of age, sex, or UPDRS score with VO 2

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Section: Discussionmentioning

confidence: 99%

Walking economy in people with Parkinson's disease

et al. 2009

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“…However, to date, no known study exists using aerobic exercise, PD, and the BP. Recent support has shown that, in combination with regular PD medication (Bergen et al 2002) and when medication is removed (M€ uller and Muhlack 2010), aerobic exercise not only improves cardiovascular function but also alleviates common symptoms of akinesia and bradykinesia when compared to age-and behavior-matched controls. One interesting venue for exploration is whether aerobic exercise is able to recapture early BP in PD patients.…”

Section: Future Considerationsmentioning

confidence: 99%

The influence of an acute bout of aerobic exercise on cortical contributions to motor preparation and execution

et al. 2014

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Increasing evidence supports the use of physical activity for modifying brain activity and overall neurological health. Specifically, aerobic exercise appears to have a positive effect on cognitive function, which some have suggested to be a result of increasing levels of arousal. However, the role of aerobic exercise on movement‐related cortical activity is less clear. We tested the hypothesis that (1) an acute bout of exercise modulates excitability within motor areas and (2) transient effects would be sustained as long as sympathetic drive remained elevated (indicated by heart rate). In experiment 1, participants performed unimanual self‐paced wrist extension movements before and after a 20‐min, moderate intensity aerobic exercise intervention on a recumbent cycle ergometer. After the cessation of exercise, Bereitschaftspotentials (BP), representative cortical markers for motor preparation, were recorded immediately postexercise (Post) and following a return to baseline heart rate (Post[Rest]). Electroencephalography (EEG) was used to measure the BP time‐locked to onset of muscle activity and separated into three main components: early, late and reafferent potentials. In experiment 2, two additional time points postexercise were added to the original protocol following the Post[Rest] condition. Early BP but not late BP was influenced by aerobic exercise, evidenced by an earlier onset, indicative of a regionally selective effect across BP generators. Moreover, this effect was sustained for up to an hour following exercise cessation and this effect was following a return to baseline heart rate. These data demonstrate that acute aerobic exercise may alter and possibly enhance the cortical substrates required for the preparation of movement.

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“…2005; Farley, 2004;National Parkinson Foundation, 2005;Weiner, Shulman, & Lang, 2001). Studies involving individuals with PD have shown that exercise can be beneficial in improving movement initiation (Bergen et al, 2002), short-step gait (Miyai et al, 2002), flexibility and physical function (Palmer, Mortimer, Webster, Bistevins, & Dickinson, 1986;Schenkman et al, 1998), and quality of life (Baatile, Langbein, Weaver, Maloney, & Jost, 2000;Reuter, Engelhardt, Stecker, & Baas, 1999).…”

mentioning

confidence: 99%

Tai Chi–Based Exercise for Older Adults with Parkinson’s Disease: A Pilot-Program Evaluation

Harmer²,

Fisher³

et al. 2007

Journal of Aging and Physical Activity

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The primary objective of this study was to provide preliminary evaluation of the feasibility, safety, and efficacy of a newly developed Tai Chi-based exercise program for older adults with Parkinson’s disease (PD). Using a one-group pretest-posttest design, 17 community-dwelling adults (mean age 71.51 years) with mild to moderate idiopathic PD (Stage I, II, or III on the Hoehn and Yahr scale) and stable medication use completed a 5-day, 90-min/day Tai Chi exercise-evaluation program. Outcome measures included face-to-face exit interviews on appropriateness and safety and physical performance (i.e., 50-ft speed walk, up-and-go, functional reach). At the end of this brief intervention, exercise adherence was 100% and the program was shown to be safe. Exit interviews indicated that the program was well received by all participants with respect to program appropriateness, participant satisfaction and enjoyment, and intentions to continue. Furthermore, a significant pretest-to-posttest change was observed at the end of the 5-day program in all three physical-performance measures (p < .05). The results of this pilot evaluation suggest that Tai Chi is an appropriate physical activity for older adults with PD and might also be useful as a therapeutic exercise modality for improving and maintaining physical function. These preliminary findings warrant further investigation.

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Aerobic exercise intervention improves aerobic capacity and movement initiation in Parkinson's disease patients

Cited by 115 publications

References 30 publications

Walking economy in people with Parkinson's disease

Walking economy in people with Parkinson's disease

The influence of an acute bout of aerobic exercise on cortical contributions to motor preparation and execution

Tai Chi–Based Exercise for Older Adults with Parkinson’s Disease: A Pilot-Program Evaluation

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