This study aimed to examine the notable distinctions in anthropometric measurements, cardio-respiratory indicators, and body composition parameters among secretarial staff at Prince Abubakar Audu University in Anyigba. The researchers employed a complete enumeration procedure to select secretarial staff from the university's seven faculties. The anthropometric variables considered included body girth measurements such as thigh, mid-thigh, hip, wrist (both relaxed and contracted), waist circumference, upper arm length, lower arm length, upper leg length, and lower leg length. Physiological parameters, such as resting heart rate, systolic blood pressure, and diastolic blood pressure, were also recorded. Descriptive statistics, including mean and standard deviation, were utilized to summarize the collected data, while inferential statistics, specifically ANOVA, were employed to compare the measurements across the seven faculties. The results indicated that the faculty of education exhibited the highest values for these parameters among the groups. Based on these findings, it can be concluded that the secretarial staff in the study area generally had low skinfold measurements. One of the recommendations arising from the study is that the secretarial staff should engage in regular physical fitness activities.