Aerobic Interval Training vs. Moderate Continuous Training in Coronary Artery Disease Patients: A Systematic Review and Meta-Analysis

Pattyn, Nele; Coeckelberghs, Ellen; Buys, Roselien; Cornelissen, Véronique; Vanhees, Luc

doi:10.1007/s40279-014-0158-x

Cited by 115 publications

(117 citation statements)

References 54 publications

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“…An increase in peak VO 2 after exercise training is well documented, [29][30][31][32] and our group already demonstrated that the OUES shows a similar response to training in CAD patients. 10 Furthermore, previous research showed that cardiac rehabilitation reduces the risk for future fatal and non-fatal events in patients with CAD.…”

Section: Discussionsupporting

confidence: 62%

“…18,31,33,35,38 Thus, an increase in exercise capacity is related to a reduction of all-cause and CV events. 22,32,34,36,39 Regarding submaximal measures of exercise capacity, one study in patients with CAD found an increase in exercise capacity, expressed in metabolic equivalent of the task, of 32% after a 12-week cardiac rehabilitation program. They calculated the Duke prognostic risk score, which is a validated risk score that predicts 5-year CV mortality using data from an exercise tolerance test, and found that the risk for CV mortality decreased by 33% among their study participants.…”

Section: Discussionmentioning

confidence: 99%

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Prognostic value of the post-training oxygen uptake efficiency slope in patients with coronary artery disease

Buys

Coeckelberghs

Cornelissen

et al. 2016

Eur J Prev Cardiolog

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Background: Peak oxygen uptake is an independent predictor of mortality in patients with coronary artery disease (CAD). However, patients with CAD are not always capable of reaching peak effort, and therefore submaximal gas exchange variables such as the oxygen uptake efficiency slope (OUES) have been introduced. Baseline exercise capacity as expressed by OUES provides prognostic information and this parameter responds to training. Therefore, we aimed to assess the prognostic value of post-training OUES in patients with CAD. Methods: We included 960 patients with CAD (age 60.6 AE 9.5 years; 853 males) who completed a cardiac rehabilitation program between 2000 and 2011. The OUES was calculated before and after cardiac rehabilitation and information on mortality was obtained. The relationships of post-training OUES with all-cause and cardiovascular (CV) mortality was assessed by Cox proportional hazards regression analyses. Receiver operator characteristic curve analysis was performed in order to obtain the optimal cut-off value. Results: During 7.37 AE 3.20 years of follow-up (range: 0.45-13.75 years), 108 patients died, among whom 47 died due to CV reasons. The post-training OUES was related to all-cause (hazard ratio: 0.50, p < 0.001) and CV (hazard ratio: 0.40, p < 0.001) mortality. When significant covariates, including baseline OUES, were entered into the Cox regression analysis, post-training OUES remained related to all-cause and CV mortality (hazard ratio: 0.40, p < 0.01 and 0.26, p < 0.01, respectively). In addition, the change in OUES due to exercise training was positively related to mortality (hazard ratio: 0.49, p < 0.01). Conclusion: Post-training OUES has stronger prognostic value compared to baseline OUES. The lack of improvement in exercise capacity expressed by OUES after an exercise training program relates to a worse prognosis and can help distinguish patients with favorable and unfavorable prognoses.

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Section: Discussionsupporting

confidence: 62%

Section: Discussionmentioning

confidence: 99%

Prognostic value of the post-training oxygen uptake efficiency slope in patients with coronary artery disease

Buys

Coeckelberghs

Cornelissen

et al. 2016

Eur J Prev Cardiolog

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“…The purpose of HIIT is to repeatedly stress the physiological system (7). In 2010-2014, several reviews and meta-analyses of HIIT for CAD and CHF were published (8)(9)(10)(11)(12)(13)(14), reflecting its increasing interest in the field of cardiac rehabilitation. One of these studies (11) involving more than 260 patients, the superiority of HIIT in patients with CAD was demonstrated.…”

Section: Introductionmentioning

confidence: 99%

Review of High-intensity Interval Training in Cardiac Rehabilitation

2016

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For the secondary prevention of cardiovascular disease, comprehensive cardiac rehabilitation is required. This involves optimal medical therapy, education on nutrition and exercise therapy, and smoking cessation. Of these, efficient exercise therapy is a key factor. A highly effective training protocol is therefore warranted, which requires a high rate of compliance. Although moderate-intensity continuous training has been the main training regimen recommended in cardiac rehabilitation guidelines, high-intensity interval training has been reported to be more effective in the clinical and experimental setting from the standpoint of peak oxygen uptake and central and peripheral adaptations. In this review, we illustrate the scientific evidence for highintensity interval training. We then verify this evidence and discuss its significance and the remaining issues.

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“…In patients with CAD with preserved or reduced LVEF, HIIAT showed to be superior to moderate MCT to improve VO 2peak , which is closely related to long-term survival in cardiac patients [26].…”

Section: Beneits Of Cardiac Rehabilitation In Cardiac Diseases: Coronmentioning

confidence: 89%

Physical Training Programs After Coronary Artery Bypass Grafting

Aikawa¹,

Kondo²,

Guillermo³

et al. 2017

Coronary Artery Bypass Graft Surgery

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Exercise-based rehabilitation is considered an important adjunct therapy for secondary prevention in patients with coronary artery disease, mainly in populations with coronary artery bypass graft (CABG) and percutaneous coronary intervention. Thus, the increasing number of cardiac surgeries along the years is enlarging the participation of patients in cardiac rehabilitation programs. Encouraging exercise-based cardiac rehabilitation might decreases in-hospital stay, speeds returns to work and reduces costs in public health. Recently, two training modalities of exercise gained much atention in cardiac rehabilitation programs: continuous exercise and high-intensity interval aerobic training (HIIAT). The aim of this chapter is to review the efects of HIIAT in patients that undergone to CABG or other cardiac surgeries regarding clinical and physiological parameters such as death, cardiovascular outcomes, aerobic capacity, anaerobic capacity, quality of life and other parameters, beyond to evaluate the feasibility and safety of HIIAT in this patient's group.

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Aerobic Interval Training vs. Moderate Continuous Training in Coronary Artery Disease Patients: A Systematic Review and Meta-Analysis

Abstract: In CAD patients with preserved and/or reduced LVEF, AIT is superior to MCT for improving peakVO2, while MCT seems to be more effective in reducing body weight. However, large, well-designed, randomized controlled trials are warranted to confirm these findings.

Cited by 115 publications

References 54 publications

Prognostic value of the post-training oxygen uptake efficiency slope in patients with coronary artery disease

Prognostic value of the post-training oxygen uptake efficiency slope in patients with coronary artery disease

Review of High-intensity Interval Training in Cardiac Rehabilitation

Physical Training Programs After Coronary Artery Bypass Grafting

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