Aerococcus sanguicola sp. nov., isolated from a human clinical source.

Lawson, Paul A.; Falsen, Enevold; Truberg-Jensen, Kjeld; Collins, Matthew D.

doi:10.1099/00207713-51-2-475

Cited by 44 publications

(21 citation statements)

References 16 publications

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“…Differentiation from A. viridans relies on positive reactions for leucine arylamidase and beta-glucoronidase [3]. Besides A. viridans and A. urinae, three additional Aerococcus species have been recently isolated from the human vagina, Aerococcus christensenii [11], and from human urine, A. urinaehominis and Aerococcus sanguicola, respectively [12,13]. However, the pathogenic importance of these latter organisms remains unknown.…”

Section: Discussionmentioning

confidence: 98%

Aerococcus urinae Endocarditis: Case Report and Review of the Literature

Ebnother¹,

Altwegg

Gottschalk

et al. 2002

Infection

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Aerococcus urinae is a rare cause of urinary tract infections, mainly in elderly men with underlying urinary tract pathologies. In addition, it has been described as a pathogen in balanitis, soft tissue infections, septicemia and endocarditis. To date ten cases of A. urinae endocarditis have been reported in the literature with a high rate of mortality (7/10) and morbidity, as two out of three survivors suffered from neurovascular complications. Here we present the case of an additional patient who was successfully treated with surgical valve replacement and antibiotic therapy consisting of ceftriaxone and netilmicin for 6 weeks. Furthermore, we review all reported cases of A. urinae endocarditis with emphasis on predisposing factors and therapeutic options.

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Section: Discussionmentioning

confidence: 98%

Aerococcus urinae Endocarditis: Case Report and Review of the Literature

Ebnother¹,

Altwegg

Gottschalk

et al. 2002

Infection

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“…LV 65.5:W1 (AF076639) (Bratina et al 1998), Pediococcus urinaeequi (D87677) (Nageshima unpubl. ), bacterium B16S (AF300974) (Allen et al 2001), Aerococcus urinaehominis (AJ278341) (Lawson et al 2001a), Aerococcus christensenii (Y17005) (Collins et al 1999), Aerococcus urinae (M77819) (Aguirre & Collins 1992), Aerococcus sanguicola (AJ276512) (Lawson et al 2001b), Facklamia hominis (Y10772) (Collins et al 1997).…”

Section: Methodsmentioning

confidence: 99%

Genetic characterization of the lobster pathogen Aerococcus viridans var. homari by 16S rRNA gene sequence and RAPD

Greenwood

Keith²,

Despres³

et al. 2005

Dis. Aquat. Org.

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A combination of 16S rRNA sequencing and random amplified polymorphic DNA (RAPD) analysis was used to evaluate the genetic diversity within Aerococcus viridans var. homari, the causative agent of gaffkemia in lobsters. A collection of 7 A. viridans var. homari strains and 2 avirulent A. viridans-like cocci isolated from homarid lobsters harvested from different regions on the Atlantic Coast of North America were analyzed. The isolates are separated geographically and temporally between the years 1947 and 2000. Sequencing of 16S rRNA genes confirmed the inclusion of all 9 isolates in the monophyletic A. viridans clade (99.8 to 100% similarity). RAPD analysis revealed that the 9 A. viridans var. homari isolates could be separated into 2 distinct subtypes. Subtype 1 included the 7 pathogenic lobster isolates and constituted a homogeneous group regardless of their geographical, temporal or virulence differences. Subtype 2 contained the 2 avirulent A. viridans-like cocci that had distinct RAPD patterns and clustered separately with the non-marine A. viridans. RAPD analysis represented a useful method for determining molecular subtyping for the intraspecific classification and epidemiological investigations of A. viridans var. homari.

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“…Eight cultures were obtained from patients residing in the United States: five (two males and three females, all more than 69 years of age) had urinary tract infections, and three had positive blood cultures, one with sepsis, one with suspected endocarditis, and the other without a diagnosis. The remaining isolate was the type strain isolated from a blood culture of a patient living in Denmark (14). Table 5 lists the antimicrobial susceptibilities of 15 strains of A. sanguinicola to 17 different drugs.…”

Section: Vol 41 2003mentioning

confidence: 99%

“…The description of the new species Aerococcus urinae complicated the differentiation of the Aerococcus genus from the other non-chain-forming GPC because A. urinae cultures gave reactions in PYR and LAP opposite to those of A. viridans (1). With the description of additional species of aerococci, A. sanguinicola (14), A. christensenii (8), and A. urinaehominis (13), the differentiation of the members of the genus Aerococcus from the other nonchaining-forming GPC became even more difficult. The descriptions of the latter three species were made with a single strain each and based on the uniqueness of their 16S rRNA gene sequences.…”

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confidence: 99%

Phenotypic Description and Antimicrobial Susceptibilities of Aerococcus sanguinicola Isolates from Human Clinical Samples

Facklam

Lovgren²,

Shewmaker

et al. 2003

J Clin Microbiol

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This report describes the clinical sources and phenotypic characterization of 16 isolates of Aerococcus sanguinicola. Sixteen conventional tests were used to describe and differentiate the 16 isolates of A. sanguinicola from 30 strains of Aerococcus viridans, 27 strains of Aerococcus urinae, and a single strain each of Aerococcus christensenii and Aerococcus urinaehominis. The phenotypic characterizations of the type strains for each species and 14 A. sanguinicola isolates were also compared in the two reference laboratories. A. sanguinicola are catalase-negative, vancomycin-susceptible, gram-positive cocci arranged in clusters and tetrads, as are all Aerococcus species except A. christensenii (which is arranged in short chains). All 16 isolates of A. sanguinicola were leucine aminopeptidase and pyrrolidonylarylamidase positive, which is unique to this species among the aerococci. All A. sanguinicola isolates grew in broth containing 6.5% NaCl, hydrolyzed hippurate, and were variable in the bile-esculin test. None of the isolates deaminated arginine or were Voges-Proskauer positive. The type strain of A. sanguinicola was isolated from a blood culture of a patient living in Denmark. Seven additional isolates were from patients living in Canada, all with urinary tract infections (six were female). Eight isolates were from patients living in five different states in the United States; five were from patients with urinary tract infections, and three were from blood cultures of one patient each with pneumonia, suspected endocarditis, and unknown clinical conditions. The antimicrobial susceptibility patterns were unremarkable; all isolates tested were susceptible to penicillin, amoxicillin, cefotaxime, cefuroxime, erythromycin, chloramphenicol, vancomycin, quinupristin-dalfopristin (Synercid), rifampin, linezolid, and tetracycline. Six of the 15 cultures were resistant to ciprofloxacin and levofloxacin, but all 15 strains were susceptible to sparfloxacin. High-level resistance was detected for meropenem (2 strains) and trimethoprim-sulfamethonazole (1 strain). Intermediate resistance was detected for trimethoprim-sulfamethoxazole (10 strains) and clindamycin (3 strains).Aerococci are gram-positive cocci (GPC) that are arranged in tetrads and clusters. No chains are observed when Gram stains are prepared from growth in broth or agar cultures. Other genera that are GPC and catalase-negative that form clusters or tetrads (Alloiococcus, Dolosigranulum, Gemella, Helcococcus, Pediococcus, and Tetragenococcus) are differentiated from the Aerococcus species by a combination of phenotypic characteristics (9). Prior to 1992, only a single species, Aerococcus viridans, was included in the genus. Since 1992, four additional species have been described: Aerococcus urinae, Aerococcus sanguinicola, Aerococcus christensenii, and Aerococcus urinaehominis. Prior to the description of the new species, Aerococcus viridans was the only non-chain-forming GPC that was pyrrolidonylarylamidase (PYR) positive and leucine aminopeptidase (LAP) n...

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Aerococcus sanguicola sp. nov., isolated from a human clinical source.

Cited by 44 publications

References 16 publications

Aerococcus urinae Endocarditis: Case Report and Review of the Literature

Aerococcus urinae Endocarditis: Case Report and Review of the Literature

Genetic characterization of the lobster pathogen Aerococcus viridans var. homari by 16S rRNA gene sequence and RAPD

Phenotypic Description and Antimicrobial Susceptibilities of Aerococcus sanguinicola Isolates from Human Clinical Samples

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