Optimisation methods in conjunction with CFD are a key tool in advancing current rotor design. High-fidelity optimisation of unsteady rotor flows in forward flight, however, is a challenging problem due to the high computational resources required. To minimize the computational costs, a fully-turbulent, overset, adjoint, harmonic balance, optimisation framework has been developed, which maintains the fidelity of the Navier-Stokes equations. The framework is demonstrated in the aerodynamic re-design of the AH-64A rotor blade. An analysis of the optimised rotor blade is presented, including the key design features that contribute to the performance benefits in each of the examined design conditions. In particular, the benefits and drawbacks of rotor designs with an offloaded blade tip have been discussed. The formulation